Broncho wax: instructions for use, composition and properties

Release form and composition

Broncho-Vaxom is produced in the form of capsules: size No. 3, opaque, gelatin hard, with a blue cap, body - blue (dosage 7 mg) or white (dosage 3.5 mg); the contents of the capsules are pale beige powder (10 pieces in blisters, 1 or 3 blisters in a cardboard pack).

1 capsule contains:

• active ingredient: standardized lyophilisate of bacterial lysates (Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Klebsiella ozaenae, Klebsiella pneumoniae, Moraxella catarrhalis) – 7 mg (Broncho-Vaxom adult) or 3.5 mg (Broncho-Vaxom children's);
• additional components (7/3.5 mg): pregelatinized starch – 110/110 mg; sodium glutamate – 3.03/1.515 mg; anhydrous propyl gallate (E310) – 0.084/0.042 mg; mannitol – up to 40/20 mg, magnesium stearate – 3/3 mg, mannitol – up to 200/200 mg;
• capsule shell (7/3.5 mg): gelatin - to obtain 50/50 mg, titanium dioxide (E171) - 1/1 mg, indigo carmine (indigotine) dye (E132) - 1/1 mg.

Instructions:

Clinical and pharmacological group

14.010 (Immunostimulating drug of bacterial origin)

Release form, composition and packaging

Broncho-Vaxom adult

Lyophilisate in hard gelatin capsules, with a blue opaque cap and a blue opaque body, with the engraving “Broncho-Vaxom”.

Excipients: pregelatinized starch, magnesium stearate, mannitol, indigotin (E132), titanium dioxide (E171), gelatin.

10 pieces. - blisters (1) - cardboard packs. 10 pcs. - blisters (3) - cardboard packs.

Broncho-Vaxom for children

Lyophilisate in hard gelatin capsules, with a blue opaque cap and a white opaque body, engraved with “Broncho-Vax”.

Excipients: pregelatinized starch, magnesium stearate, mannitol, indigotin (E132), titanium dioxide (E171), gelatin.

10 pieces. - blisters (1) - cardboard packs. 10 pcs. - blisters (3) - cardboard packs.

pharmachologic effect

Immunostimulating drug of bacterial origin. Increases humoral and cellular immunity. Stimulates peritoneal macrophages, increases the number of T-lymphocytes and increases the formation of immunoglobulins A, G, M, secreted by the mucous membrane of the respiratory tract. The immunostimulating effect of the bacterial lysate is due to its effect on Peyer's patches in the gastrointestinal mucosa.

Clinically, Broncho-Vaxom reduces the frequency of acute infections, shortens the duration of their course, reduces the severity of symptoms, and also reduces the likelihood of exacerbation of chronic diseases. This reduces the need to use other medications, especially antibiotics.

Pharmacokinetics

Data on the pharmacokinetics of the drug Broncho-Vaxom are not provided.

Dosage

Adults and children over 12 years of age are recommended to use the drug Broncho-Vaxom for adults. Children aged 6 months to 12 years should use Broncho-Vaxom for children.

For the treatment of acute and exacerbation of chronic respiratory infections, the drug is prescribed 1 caps. 1 time/day The drug should be taken in the morning on an empty stomach, daily, for at least 10 days. The duration of treatment is determined individually based on the patient's condition. If antibiotic therapy is necessary, Broncho-Vaxom should be taken in combination with an antibiotic from the beginning of treatment.

To prevent exacerbations of chronic respiratory infections and as maintenance therapy, 1 capsule/day is prescribed daily in the morning on an empty stomach. The course of treatment includes 3 cycles of 10 days, the interval between cycles is 20 days.

If the child has difficulty swallowing the capsule, it should be opened and its contents mixed with drink (fruit juice, milk).

Overdose

There is currently no information on cases of overdose of the drug Broncho-Vaxom.

Drug interactions

The interaction of the drug Broncho-Vaxom with other drugs has not yet been established.

Use during pregnancy and lactation

The drug is contraindicated for use in the first trimester of pregnancy and lactation.

Side effects

From the digestive system: nausea, abdominal pain, vomiting.

Dermatological reactions: itching, erythema.

From the respiratory system: cough, shortness of breath.

From the side of the central nervous system: headache, feeling of fatigue.

Storage conditions and periods

The drug should be stored in a dry place, protected from light, out of reach of children at a temperature of 15° to 25°C. Shelf life: 5 years.

Indications

— treatment of infectious diseases of the respiratory tract (including as part of combination therapy);

- prevention of recurrent infections of the upper and lower respiratory tract (including chronic bronchitis, tonsillitis, pharyngitis, laryngitis).

Contraindications

- children up to 6 months;

— I trimester of pregnancy;

- lactation period;

- hypersensitivity to the components of the drug.

special instructions

Broncho-Vaxom can be used simultaneously with other drugs in the treatment of respiratory diseases.

The patient should be warned that in case of persistent dyspeptic symptoms, skin and respiratory reactions, the use of Broncho-Vaxom should be stopped, as this may be a manifestation of allergic reactions, and consult with the attending physician.

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Pharmacological properties

Pharmacodynamics

Broncho-Vaxom is an immunostimulating agent of bacterial origin that causes an immune response in the mucous membrane of the gastrointestinal tract. The most pronounced effect is observed in Peyer's patches (PB) of the small intestine, which is manifested in the activation of antigen-presenting cells (APC) and further stimulation of cells responsible for specific immunity.

During the period of use of the drug, an increase in the level of circulating B-lymphocytes is observed. After stimulation of the latter, there is an increase in the production of polyclonal antibodies, mainly IgG (immunoglobulin G) serum and IgA (immunoglobulin A), secreted by saliva and the mucous membrane of the respiratory tract. These antibodies are the first line of defense against a number of pathogenic viruses and bacteria.

Due to the powerful stimulating effect of the drug on most types of leukocytes, the number of lymphoid and myeloid cells increases, and there is also a selective increase in the expression of receptors on their surface.

All these data together confirm that the drug helps strengthen the body's immune defense against infections.

Clinically, Broncho-Vaxom reduces the incidence and duration of acute respiratory infections and reduces the risk of exacerbation of chronic bronchitis. This entails a reduced need for the use of other drugs, especially antibiotics.

Pharmacokinetics

Data on the pharmacokinetics of the drug are not provided.

Broncho-Vaxom

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Directions for use and dosage

Broncho-Vaxom capsules are taken orally, 1 piece daily. in the morning, on an empty stomach.

Adults and adolescents from 12 years old – Broncho-Vaxom adult (7 mg capsules); children from 6 months to 12 years – Broncho-Vaxom for children (capsules 3.5 mg).

For the treatment of acute forms and exacerbations of chronic respiratory infections, the drug is recommended to be used until the symptoms of the disease subside, but for at least 10 days. The duration of treatment is determined by the attending physician depending on the patient’s condition. If it is necessary to prescribe antibiotic therapy, Broncho-Vax must be taken in combination with an antibiotic from the first day of treatment.

When carrying out maintenance therapy, as well as for the purpose of preventing exacerbations, the drug is taken in a course of 3 cycles, each of which lasts 10 days. The breaks between cycles should be 20 days.

If you have difficulty swallowing the capsule, you can open it and take only the contents, mixing it with water, fruit juice or milk.

Broncho wax: indications and contraindications

The drug is recommended for use in the following cases: 1. In mono - and as part of combination therapy in cases of respiratory tract disease of an infectious nature. 2. To prevent relapses of lower and upper respiratory tract infections: - tonsillitis; - laryngitis; - Chronical bronchitis; - pharyngitis...

Contraindications

- first trimester of pregnancy; - hypersensitivity to the components of the drug; - period of breastfeeding (lactation); - age up to 6 months.

Side effects

• nervous system: frequency unknown – headache;
• respiratory system: often – cough;
• digestive system: often – abdominal pain, diarrhea; frequency unknown - nausea, vomiting;
• allergic reactions: uncommon - hypersensitivity reactions (shortness of breath, peripheral edema, swelling of the eyelids, swelling/edema of the face, erythematous/generalized rash, erythema, itching, including generalized); frequency unknown - Quincke's edema, urticaria;
• dermatological reactions: often - rash;
• other reactions: frequency unknown - fatigue, fever.

Broncho wax: price and sale

Since the drug is quite common, you can buy Broncho Vax without any problems at any pharmacy. In addition, you can purchase it by filling out an application online. Broncho wax, the price of which may be slightly lower when purchased secondhand, is still better to purchase in places specially designed for the sale of medical drugs. Since at the pharmacy you can verify that the product has a certificate of conformity, it is better not to take risks and buy medications at the pharmacy or at the official representative offices of the manufacturer.

special instructions

Some of the components of the drug can lead to a hypersensitivity reaction. If gastrointestinal disorders, respiratory disorders, skin reactions or other signs of intolerance to the drug persist for a long time, use should be discontinued, since these effects are allergic in nature.

Impact on the ability to drive vehicles and complex mechanisms

The drug does not affect the ability to drive vehicles and other machinery.

Broncho wax and Transfer factor

(very important note) The cost of Broncho Vaxom is on average about 1000 rubles. for 10 capsules, a course of therapy requires about 30 capsules, i.e. A course of treatment with this drug will cost about 3,000 rubles. , and the result is not guaranteed and requires repeated repetition. Exactly the same functions are performed by Transfer Factor, which contains 90 capsules in a package and costs about 2,000 rubles. Only TF has no contraindications and does not cause any side effects; it is impossible to overdose and has no age restrictions. Among other things, its effect on our body is deeper and more dramatic - it puts in order damaged human DNA, i.e. removes the cause of the disease, rather than treating its consequences. But if you still decide to take Broncho wax, then we advise you to take it with TF in combination, because When taken in such a complex manner, TF neutralizes all its side effects. Here you will read about the use of TF for various diseases.