Diazolin is well known to modern parents from their own childhood. This is a first-generation antihistamine, which our mothers most often gave us for various allergic manifestations. First generation antihistamines are inferior in some properties to new drugs. For example, they have a hypnotic effect, have a quick and strong, but at the same time, short-term effect. Also, long-term use of drugs of this generation reduces antihistamine activity, so they cannot be taken for a long time.
Diazolin is still popular today. It remains one of the most accessible antihistamines. Its action and side effects have been carefully studied and tested over decades of use. We invite you to read a detailed description of this drug, and also answer a common question - is Diazolin suitable for very young children?
Pharmacodynamics and pharmacokinetics
Mebhydrolin contained in this drug is an antihistamine that blocks histamine H1 receptors. It significantly reduces the spasmogenic effect of histamine on the smooth muscles of the intestines and bronchi. It also affects vascular permeability . If we compare this drug with first-generation antihistamines, such as suprastin or diphenhydramine , then its sedative and hypnotic effects are much less pronounced. Diazolin also has anesthetic properties, but they are weak.
Absorption of the drug occurs very quickly, and after 15-30 minutes it begins to act. The maximum effect in patients is observed after 1-2 hours, while its duration is up to two days. It is excreted from the body through the kidneys.
special instructions
And although Diazolin is well tolerated, long-term use increases the likelihood of side effects. For this reason, the drug is practically not used in the treatment of chronic allergic diseases. Its main purpose is to relieve symptoms of acute allergic reactions at their earliest stages.
Unlike first-generation antihistamines, mebhydrolin slightly penetrates the central nervous system, and therefore does not have a hypnotic or pronounced sedative effect.
Relatively common side effects of Diazolin with potentially serious consequences are dizziness, blurred vision and drowsiness, therefore, during treatment with this drug, it is recommended to refrain from driving a car and performing activities that require speed of mental and/or physical reactions, visual acuity, and concentration.
During treatment with Diazolin, you should not drink alcohol-containing drinks, take sedatives and central nervous system depressants, since mebhydrolin enhances their effect.
Indications for use of Diazolin
Medicine Diazolin, what does it help with? The drug is successfully used for the prevention and treatment of manifestations of both seasonal and allergic rhinitis. The drug is prescribed to patients with hay fever , urticaria, food and drug allergies. What other indications for the use of Diazolin? It is taken in the presence of noticeable skin reactions due to bites of various insects, as well as for dermatoses that are accompanied by itching.
Interaction with other drugs
Diazolin has the ability to enhance the effect of ethanol (ethyl alcohol). Therefore, you should pay attention to whether it is included in the drugs that you give to your child in parallel with Diazolin. In addition, Diazolin increases the effect of sedatives (for example, Glycine, Persen, Notta, Dormikind, etc.). Therefore, you should consult your doctor if your child takes drugs from this group together with Diazolin.
Diazolin has a positive interaction when taken with antibiotics and deworming medications for children.
- In the case of antibacterial drugs, Diazolin helps eliminate allergic manifestations that most often occur during treatment with antibiotics.
- When getting rid of worms, Diazolin helps relieve allergic reactions due to intoxication of the body with waste products of parasites.
Contraindications
Patients who are highly sensitive to the components of diazolin should not take the drug. The drug is not prescribed to people with exacerbation of gastric and duodenal ulcers or any other inflammatory diseases of the gastrointestinal tract. A contraindication to the use of Diazolin is pyloric stenosis.
This drug should be prescribed with extreme caution if the patient has severe liver and kidney failure. In this case, you need to individually adjust the dose of the drug, as well as the number of doses. It is not recommended to prescribe Diazolin for epilepsy , angle-closure glaucoma, or for various heart rhythm disorders.
Side effects
According to the annotation, the following side effects may occur while taking the drug.
In the digestive system: possible irritation of the mucous membranes of the gastrointestinal tract, dyspeptic symptoms - nausea, heartburn , pain in the epigastric region.
In the work of the central nervous system: possible dizziness, paresthesia , high level of fatigue, increased drowsiness, slow reaction, blurred visual perception.
Also, when taking the drug, you may experience dry mouth, problematic urination, and allergic reactions. Granulocytopenia and agranulocytosis occur very rarely . The risk of side effects increases significantly with an overdose.
Paradoxical reactions are possible when children take the drug: they may experience irritability, insomnia, and tremor .
Overdose
If the prescribed one-time dosage is violated or the dose of the drug per day is exceeded, an overdose may develop. It can manifest itself with the following symptoms:
- suppression of central nervous system functions (blurred consciousness, impaired coordination, decreased concentration and reaction, hypersomnolence, blurred vision);
- stimulating effect on the central nervous system (insomnia, high excitability and anxiety, dilation of the eye pupils, tremors of the extremities);
- dry mouth, rush of blood to the upper body;
- nausea, stomach pain, vomiting, unstable stool.
In case of overdose, the risk of all side effects from the drug increases many times over. In case of overdose, the drug should be discontinued. Next, rinse the stomach, take a sorbent (activated carbon, Enterosgel or any other) and immediately consult a doctor to prescribe symptomatic therapy.
Instructions for use of Diazolin (Method and dosage)
Dragees and Diazolin tablets, instructions for use
The drug in tablets and dragees is used after meals.
How to take for adults? Children from twelve years of age, as well as adults, use the drug once or twice a day at a dose of 100-200 mg. The maximum single dose for adults should be 300 mg; adults can take 600 mg of Diazolin per day. Children five to twelve years old can take 50 mg two to three times daily. Children aged three to five years can take 50 mg of the drug 1-2 times a day. How long the treatment should last should be determined by a specialist in each specific case.
Instructions for use of Diazolin for children
Children's Diazolin is used as follows: 100 ml of warm boiled water is added to the bottle containing the granules. The contents must be mixed very thoroughly, for which you need to stir for several minutes. After this, the suspension is given to children in doses that can be easily determined using the supplied graduated glass. Dosages of children's Diazolin should be as follows: 2.5 ml - children 2-3 years old; 5 ml - children 4-6 years old; 7.5 ml – children 7-10 years old. The drug should be taken two or three times after meals for 5-7 days. The suspension must be shaken before use.
Reviews
Svetlana:
A child (3 years old) periodically develops food allergies. We excluded citrus fruits and cocoa, and still it appears from time to time. Fenistil drops do not help us. I always keep Diazolin and Loratadine at home as a first aid. They always help relieve symptoms.
Alice:
In winter we caught a cold, the child coughed non-stop! Dry cough, to the point of vomiting. It turned out to be obstructive bronchitis. The pediatrician prescribed treatment, but the child continued to suffer from coughing attacks, especially at night. Therefore, when the child started coughing completely, she gave Noshpa + Diazolin. It helped very quickly, I began to sleep normally at night. I like the pill form better; I tell my child that this is such a medicinal candy, and he never resists taking it.
Catherine:
I try to avoid Diazolin and Suprastin whenever possible. These are dinosaur drugs, you need to take them several times a day, as they are weak and make you sleepy. Fenistil is also weak, especially after a year. Therefore, I prefer something like Loratadine, Claritin, Cetrin, Eden. My child is allergic. We have been to so many doctors and talked to many about Diazolin and similar drugs. It has more side effects than results.
Olga:
My son (5 years old) was allergic to cashews. I ate quite a lot, my legs, tummy, forehead are covered in red blisters, my eyelids are swollen! I gave Fenistil 30 drops, but it didn’t help. Everything continued to itch. I had to give Diazolin, even though it is the oldest antihistamine. My relatives recommended him. And it really worked quickly.
Julia:
I am allergic to ragweed, July to September is hell. The doctor prescribed a children's dose of Diazolin because I was pregnant. I drank it along with homeopathic drops of Euphorbium compositum, sprayed saline solutions into my nose, and it really helped.
Analogues of Diazolin
Level 4 ATX code matches:
Dezal
Histaphene
Clarisens
Telfast
Erius
Claridol
Claritin
Loratadine
Fexofast
Peritol
Desloratadine
LauraHEXAL
Clarotadine
Rupafin
Ciel
Dramamine
Lordestin
Lomilan
Fenkarol
Kestin
There are no direct analogues. Unpatented synonyms: Dialin , Mebhydrolin , Omeril. Diprazin , Tavegil , Suprastin , Diphenhydramine are similar in action .
Diazolin price, where to buy
The price of Diazolin in tablets is 50 rubles for 10 pieces of 50 mg of active ingredient. The cost of the pills is 70 rubles for 10 pieces of 50 mg of mebhydrolin, and 80 rubles for 10 pieces of 100 mg.
How much do tablets cost in Kharkov? Around 5-10 UAH.
The price of children's Diazolin is about 95 rubles.
The ointment of this drug is not for sale.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Diazolin tablets 50 mg 10 pcs JSC "AVVA RUS"
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Pharmacy24
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PaniPharmacy
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- Diazolin tablets Diazolin tablets. 0.1g No. 10 Ukraine, Farmak OJSC
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