Instructions for use and reviews of Fucidin cream

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Fucidin G (Fucidin H) is a combination drug for external use. Belongs to the group of corticosteroids for the treatment of skin diseases for external use - weakly active corticosteroids in combination with antibiotics (D07CA01).

Active ingredients: Fusidic acid and Hydrocortisone. Fucidin G has anti-inflammatory, antibacterial, glucocorticoid effects. The drug is available with a doctor's prescription!

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Bicomponent drug intended for external use. Combines the antipruritic and anti-inflammatory effects of hydrocortisone with the bacteriostatic effect of fusidic acid , based on disruption of protein biosynthesis in the pathogen cell.

The most sensitive to the drug Fucidin are gram-positive microorganisms and gram-negative cocci: Streptococcus pyogenes, Neisseria meningitidis and gonorrhoeae, Staphylococcus aureus and epidemridis, Corynebacterium minutissimum, Nocardia asteroides, as well as representatives of the genera Pseudomonas and Clostridium.

The drug is not active against E. coli , as well as representatives of the genera Salmonella and Proteus, protozoa and fungi.

The antibacterial effect of fusidic acid is not weakened by the presence of hydrocortisone .

Pharmacokinetics

About 2% of the active ingredients penetrate the skin upon application. Systemic absorption is weak.

Fusidic acid is excreted mainly in the bile, and only a small small amount is evacuated from the body in the urine.

Absorbed hydrocortisone is quickly transformed and excreted in the urine.

Action

Medicines based on fusidic acid, a natural antibiotic, began to be produced in the 60s of the twentieth century. The substance inhibits the activity of staphylococci, including those resistant to penicillins, erythromycins and chloramphenicol, streptococci, meningococci, pneumococci and gonococci. By introducing itself into the cell of a pathogenic organism, it stops the production of protein in ribosomes, which is why development stops. When enhanced with hydrocotisone, the drug acquires additional properties - it stimulates regeneration and relieves itching.

Absorption is negligible. Up to 2% of fusidic acid is absorbed through epithelial tissue. In the systemic circulation, when used according to the therapeutic regimen recommended by the instructions, it is not determined. Metabolites are excreted by the intestines, a small amount is removed by the kidneys. Hydrocortisone is excreted in the urine.

Contraindications

• perioral dermatitis;
• primary infectious skin lesions caused by fungi, bacteria or viruses ( herpes , chicken pox );
• allergy to the components of the drug;
• rosacea;
• skin complications of tuberculosis or syphilis ;
• age less than 2 years.

Fucidin G should be taken with caution during pregnancy and lactation.

Application

Before treatment, the skin should be cleaned of cosmetics or household contaminants. Cream and ointment are applied in a thin layer or pointwise, directly to problem areas. To ensure even distribution, lightly rub in with massage movements. It can be used under a bandage, in this case it is limited to 1-2 procedures per day.

The duration of the therapeutic course is no longer than 2 weeks, the frequency of treatment is 2-3 times. The maximum therapeutic effect is achieved in 7 days. As soon as the painful symptoms subside, the number of application procedures is reduced to 1-2 times a day.

Fucidin cream can be used for infectious lesions of the eyelids. Apply 2 times a day, avoiding contact with the conjunctiva. Duration of treatment - within 48 hours after the disappearance of clinical manifestations.

Side effects

• Allergic phenomena: eczema, urticaria , Quincke's edema .
• Dermatological phenomena: contact dermatitis , skin irritation, eczema , skin rash and itching, dry skin, depigmentation .
• Reactions associated with the presence of hydrocortisone : telangiectasia and striae , skin atrophy, hypertrichosis , depigmentation , folliculitis , allergic contact dermatitis , perioral dermatitis , adrenal suppression.

Side effects and overdose

With individual intolerance, patients experience symptoms of individual intolerance of a localized nature:

• tingling and pain at the treatment site;
• itching and burning;
• rash;
• depigmentation;
• swelling;
• hyperemia.

With prolonged use, stretch marks and folliculitis may appear. Side effects when using Fucidin G are atrophy of epithelial tissue, suppression of the adrenal cortex. Such reactions are typical with long-term use of glucocorticosteroids. In isolated cases, systemic manifestations were described - bronchospasms, anaphylactic shock. In young children, dysfunction of the liver and adrenal cortex was noted. In adults, similar manifestations can occur with renal or liver failure.

When applied topically, the cream and ointment did not cause an overdose. At the first symptoms indicating the development of local allergic reactions, it is necessary to stop treatment and consult a doctor.

special instructions

Do not apply the cream to the skin of the eyelids, as fusidic acid causes irritation of the conjunctival tissue.

The cream contains butylated hydroxyanisole, potassium sorbate and cetyl alcohol . These substances cause the development of local allergic skin phenomena . Butylated hydroxyanisole may also cause irritation to mucous membranes and eyes.

When using fusidic acid, the development of bacterial resistance cannot be ruled out. antibacterial drug resistance . The use of chronic combinations of glucocorticosteroids with an antibiotic should not last more than 2 weeks due to the ability of the former to mask signs of infection or hypersensitivity reactions.

It is recommended to avoid prolonged use of topical glucocorticosteroids because this can lead to adrenal suppression even with low systemic absorption. After long-term treatment with glucocorticosteroids, atrophic changes may develop on the skin of the face and other parts of the body.

There was no effect of the drug on the ability to drive a car.

Release form and composition

In all dosage forms, the main active ingredient is fusidic acid hemihydrate, 20 mg per 1 g of substance. Fucidin G has a complex composition, enhanced with hydrocortisone acetate. All drugs have the same concentration - 2%. In appearance, the difference is not noticeable - the structure is uniform, homogeneous. Color: milky white.

Auxiliary composition of one-component cream: cetyl alcohol, glycerol, liquid and soft white paraffin, polysorbate 60, hydrochloric acid, potassium sorbate, butylated hydroxyanisole, purified water. Enhanced contains no butylated hydroxyanisole.

The structure of the ointment resembles a gel. The consistency is homogeneous, stickiness and greasiness, which usually arise during application, are absent. Color - light yellow or creamy white. Active ingredient - sodium fusidate, additional - lanolin, cetyl alcohol, paraffins - liquid and soft white.

All dosage forms are packaged in metal tubes. Secondary packaging is cardboard. There is no applicator for application.

Analogs

Level 4 ATC code matches:
Cortomycetin

Oxycort

Hyoxysone

Pimafukort

Hyoxysone, Pimafucort, Cortomycetin, Oxycort.

Analogs are cheaper

There are several structural analogues on our pharmaceutical market. The active substance is fusidic acid. The manufacturer, price, and composition of auxiliary components differ. The cost of analogues is from 275 rubles. up to 420 rub.

The pharmacy may offer in return:

• Fusidanate;
• Fusiderm;
• Sodium fusidate;
• Fusidic acid;
• Fucidin G;
• Fusidine sodium;
• Fucithalmic.

The issue of replacement should be discussed with a specialist.

Analogs with a similar mechanism of action:

1. Streptocide . Prescribed for the treatment of inflamed pimples and acne. The powder is turned into powder, dissolved with water, and applied to problem areas. Leave for 20 minutes, rinse with warm water. Duration of therapy is from 7 to 14 days.
2. Furacilin . Available in tablet form. It is crushed and diluted with water. Apply to pimples and blackheads. Treats purulent rashes. They are used for an average of 5 days, since with further treatment dryness and irritation appear.
3. Ampicillin. The best antibiotic with a wide spectrum of action. Helps cure severe acne. Effective for inflamed external, subcutaneous acne. Ampicillin is bought in tablets, dissolved in water. The paste is applied to problem areas. Wait 20 minutes. Wash off with warm water. Improvement is observed on the third day of therapy, but the full course consists of 7-14 days. You should not use an antibiotic without consulting a specialist.
4. Zenerite . A popular remedy for pimples and acne. The composition is hypoallergenic, therefore it is prescribed to adolescents, pregnant women, and breastfeeding women if particularly necessary. Zinerite is available in powder form, which must be dissolved with warm water. The course is long - up to 10 weeks. Improvement occurs gradually.

You can buy cheap analogues at any pharmacy. The cost of the record is from 10 rubles. Each of them is contraindicated for use in case of individual intolerance. The indicated treatment periods should not be exceeded. If the condition does not improve, consult a dermatologist.

Fucidin G price, where to buy

The price of Fucidin G cream in Russia is 410-450 rubles; in Ukraine, a similar drug costs an average of 425 hryvnia.

• Online pharmacies in RussiaRussia

ZdravCity

• Fucidin G cream 2% 15gLEO Laboratories Limited
  RUR 419 order

Use during pregnancy and pediatrics

Fucidin is prescribed to pregnant women in cases where it is impossible to choose a safer drug. Frequency of application no more than 2 times a day. The cream should be applied in a minimal amount. Treatment is carried out under the supervision of specialists. Recommended course – 7 days. Then they switch to drugs without antibiotics. For breastfeeding women the situation is similar. While using the ointment, you should stop breastfeeding.

Fucidin is used in pediatrics. Prescribed to children aged 2 years and older. Common indications are acne, inflamed pimples, acne in adolescence, when other remedies do not provide the desired therapeutic effect. Apply the cream in a thin layer to problem areas 1-2 times a day.

Reviews

Dear readers, was this article helpful? Have you used Fucidin cream and did you get the desired effect? Leave your feedback in the comments! Your opinion is important to us, and it will help our readers make a choice!

Angelina

“I have problem skin, inflamed pimples and purulent acne often appear. I read reviews on forums and bought Fucidin. I applied it to my rashes for 4 days, no signs of improvement. The acne was still inflamed and remained. The instructions indicate that you need to use the ointment for 7-10 days, but I don’t see much point. If I saw an improvement, I could continue. In general, it’s difficult for me to evaluate the effectiveness of the cream. Many people write that they help, but they don’t help me. My pimples and acne are not that bad, but, alas. In 10 days they go away on their own.”

Catherine

“I started having problems with acne as a teenager. Different treatment regimens were prescribed, the effect was short-term. As part of complex therapy, I was prescribed Fucidin. I used it spot on, only in problem areas. I applied it to acne and inflamed pimples. The cream removed my inflammation, dried it out, and pulled out ulcers. No new rashes appeared, the skin began to recover and clear up quite quickly. On the third day I already saw the results and was quietly happy. Within a week, the minor rashes disappeared and there was no inflammation left. The course was prescribed to me for 14 days. So in the second week, acne appeared again. Habituation develops very quickly. There is no point in using the cream for a long time. In general, it turned out to be weak for me, and they prescribed another antibiotic.”

Fucidin G - main differences, scope of application

A hormonal drug that contains, in addition to fusidic acid, hydrocortisone. Glucocorticosteroid hormone has a pronounced anti-inflammatory and antipruritic property. Quickly eliminates redness, inflammation, swelling. The combined effect of active components accelerates the therapeutic effect and copes with acne caused by hormonal fluctuations.

Indications for use are the presence of atopic dermatitis, complicated by a bacterial infection, as well as complex dermatological infections caused by the proliferation of pathogenic microflora.

Fucidin G has many more contraindications that you need to familiarize yourself with before starting active therapy:

• individual intolerance;
• herpetic rashes;
• primary bacterial, fungal infection;
• manifestations of syphilis, tuberculosis on the skin;
• age up to 2 years;
• rosacea;
• perioral dermatitis.

Not prescribed during pregnancy or breastfeeding. Apply precisely to areas of skin lesions 1-2 times a day. The duration of the course is no more than 14 days for adults, 7 days for children. If the instructions are followed, the therapeutic effect occurs quickly, and no undesirable manifestations are observed. Violation of recommendations, use of the cream for more than 2 weeks leads to addiction, development of secondary infection, and withdrawal effects.

The cream is sold in a 15 g tube. It must be sold in pharmacies with a prescription, but very often this rule is violated. Fucidin G is freely available on websites on the Internet. The price of the cream is 356 – 456 rubles.