Prohibited during pregnancy
Prohibited during breastfeeding
Not suitable for children
Has restrictions for older people
Has limitations for liver problems
Has limitations for kidney problems
Carnicetine is a medicine that improves a person’s cognitive abilities, including age-related dementia, through a positive effect on the metabolic processes of the brain. Due to the ability of the drug to influence the metabolism and energy supply of central nervous system tissues, it is widely used as maintenance therapy for reduced mental performance of various etiologies.
Despite the fact that Carnicetine is a dietary supplement and not a drug, before you start taking it you need to study the instructions for its use, this will avoid unwanted complications.
What is this medicine used for?
The drug "Carnicetine", the instructions for use of which are described in this article, is most often prescribed by doctors to patients with dementia in its various manifestations. The drug also has a positive effect on people who suffer from poor memory, cannot concentrate and get tired quickly.
The active components included in the drug can increase the level of acetylcholine. This is why it becomes much easier to conduct nerve impulses, and patients suffering from Alzheimer's disease begin to feel much better. Experts recommend using the drug “Carnicetine”, instructions for use of which are included in each cardboard package, for people susceptible to stress and depression. The drug is in the form of capsules. Its main active ingredient is acetyl L-carnitine.
"Carnitex"
Carnicetine is used effectively to maintain the nervous system. Its analogues are few, the most popular among them is “Carnitex”. The indications are similar (the list is presented above). The average daily dose is 6-12 capsules, and the single dosage and time of administration are determined by the doctor. For dementia, the maximum dose is 4000 mg/day, it is recommended to divide it into 2-3 doses. For neuropathies of various etiologies, 1500-3000 mg/day is prescribed. The exact dosage is selected individually for each patient.
Side effects include an allergic reaction, nausea and heartburn. Some patients report a feeling of anxiety. In addition, urine and sweat often have a specific odor.
"Carnitex" should not be taken under the age of 18, and during pregnancy it is prescribed only under strict doctor's instructions. The drug can be called safe if the instructions and instructions of the doctor are followed, but combination use with certain medications is not recommended. You should not combine Carnitex with Acenocoumarol. If simultaneous use with Warfarin is necessary, careful medical monitoring of the patient's condition is required.
The biological supplement “Carnicetine” (instructions for use are presented in the article) is an excellent tool for activating mental activity and protecting the nervous system. The effect is observed after a course of taking the supplement. If the desired result is not achieved, the drug may be replaced or the dosage adjusted. The drug "Carnicetine" is well tolerated by patients and has virtually no contraindications, but before taking it it is better to consult a therapist.
What is dementia and how to cope with it
Senile dementia of the Alzheimer's type is in other words called senile dementia. Most often, this disease is associated with Alzheimer's disease. It manifests itself in excessively rapid changes occurring in brain cells. This pathology occurs mainly in people over eighty years of age, as well as in people with poor genetic inheritance.
Also, this disease often begins to progress very quickly in people who are very overweight, with traumatic brain injuries, with physical inactivity and diabetes.
The drug "Carnicetine", the instructions for use of which are described in the article, can have a positive effect only in the initial stages of dementia. The main symptoms of this disease are weakening of memory and decreased concentration. The sick patient does not remember where he put things, what he ate today, and also ceases to navigate even in places that are well known to him.
Using the drug "Carnicetine", the price of which is indicated below, you can cope with the symptoms that bother you. However, unfortunately, you will not be able to overcome the disease itself. However, doctors recommend using other medications at the same time in order to minimize the rate of progression of this pathology.
General information about Carnicetine
The drug is a synthetic substitute for a natural biological component that is present in almost all tissues of the body and is involved in the metabolism of carbohydrates and fatty acids. The medication improves memory and helps the brain better assimilate new information, and thanks to its ability to reduce the brain's need for oxygen, it protects its tissues from ischemia.
Carnicetine has three very pronounced pharmacological properties:
- neuroprotective;
- metabolic;
- cholinomimetic.
Unlike most dietary supplements, Carnicetine cannot be purchased in pharmacies without a prescription from a specialist.
Drug group, INN, scope of application
Carnicetine is a metabolite that has a positive effect on human mental abilities and learning speed. Due to its pharmacological activity, the medication is prescribed to people with dementia, involutional syndromes and various peripheral neuropathies, which have led to memory impairment and reduced concentration.
INN of the drug is Acetylcarnitine.
Release forms and prices in popular pharmacies
The biological additive is produced in the form of gelatin capsules placed in a polymer jar or cell packaging. External characteristics of the dosage form: plain, white, opaque. The capsules contain white or almost white powder, without dark inclusions.
The cost of the medication in various pharmacies in the Russian Federation:
Implementation form | Pharmacy, city | Price, rubles |
Capsules 295 mg, No. 60 | Samson-Pharma, Moscow | 568 |
"Zdrav-City", St. Petersburg | 542 | |
"Pharmacy 36.6", Tomsk | 528 | |
"Neuron", Krasnoyarsk | 590 | |
"Violet", Rostov-on-Don | 536 | |
"Avesta", Novosibirsk | 543 |
Compound
The drug consists of acetylcarnitine hydrochloride (295 mg) and auxiliary components, including silicon dioxide, magnesium stearate and cellulose.
Acetylcarnitine is a substance involved in fat catabolism and energy formation. Present in almost all tissues of the body, including brain tissue (BM), and promotes the process of memorizing new skills.
The capsule is made of gelatin with the addition of glycerol, nipagin, sodium lauryl sulfate, napizole, titanium dioxide and purified water.
Pharmacodynamics
The drug has the following pharmacological effects:
- metabolic;
- antiamnestic;
- neuroprotective;
- neurotrophic;
- cholinomimetic;
- light antioxidant.
Acetylcarnitine is synthesized directly by the body. The formation of the substance occurs in the liver, kidneys and GM, due to the action of the enzyme carnitine acetyltransferase. This substance is involved in the breakdown of fats and energy formation. The drug improves energy metabolism in the body by promoting the use of fatty acids, rather than carbohydrates, as the main source of energy. It is a component that triggers energy-dependent metabolic processes in mitochondria.
Psychostimulants
Acetylcarnitine has a structural similarity to acetylcholine and, like it, has a cholinomimetic effect. The substance also acts as a stimulating factor in the formation of phospholipids and proteins, which are involved in the formation and regeneration of membranes. This effect of the drug accelerates the recovery of neurons after traumatic and endocrine damage to peripheral nerves due to diabetes mellitus.
The substance protects brain tissue from oxygen starvation, since it provides the body with energy with little oxygen consumption by the tissues of the nervous system. Carnicetine slows down the process of decreasing the concentrations of taurine, aspartic and glutamic acids in neurons during aging.
In the case of long-term treatment with the drug, an increase in the density of N-methyl-D-aspartate receptors is observed, which does not decrease even during the aging process of the hippocampus and cerebral cortex.
Slowing down the aging process also occurs due to the substance’s ability to enhance the flow of fatty acids into mitochondria and support their active functioning. It is the leading link in the Krebs cycle.
The drug modulates the activity of nerve growth factor, producing a neurotrophic effect.
In addition, an increase in the effect of serotonin and a decrease in the neurotoxic effects of glutamate and ammonia were recorded when taking acetylcarnitine. Due to the membrane-stabilizing and anti-amnestic effects of Carnicetine, the drug is used as an experimental treatment for Alzheimer's disease. But unlike other drugs that are used to treat this disease, Carnicetine does not have a sedative or muscle relaxant effect.
The substance slows down the aging process and improves human cognitive abilities, especially attention and memory.
Pharmacokinetics
The pharmacokinetics of the drug have been studied exclusively in animals. According to the results of the study, the maximum concentration of the drug in the body after oral administration is observed after 4 hours. The amount of medication, after reaching the maximum concentration, does not change for 8 hours.
The drug enters the bloodstream through absorption through the gastric mucosa and through active transport. Acetylcarnitine enters most tissues of the body, including brain tissue, unchanged, with the exception of the liver and small intestine. A direct energy-dependent process against a concentration gradient delivers a substance to the cells of the body.
It is broken down to the active metabolite - carnitine, under the action of plasma esterases. The route of excretion is in the urine.
See also:
Omaron - instructions for use, reviews, analogues and indications
Decreased performance level
Carnicetine tablets are an excellent panacea for patients who suffer from a reduced level of performance. This condition is characterized by a noticeable loss of strength. An improper daily routine, as well as constant stress, gradually exhausts the human body. The nervous system gets tired and just starts to malfunction. Individuals suffering from overfatigue are unable to work productively and also cannot concentrate on the desired object.
The drug "Carnicetine", reviews of which are mostly positive, not only combats the symptoms listed above, but is also able to elevate mood and increase the body's overall resistance to stress. However, the product will have a positive effect only if it is used correctly.
Pharmacological properties
Acetylcarnitine is a biologically active l-carnitine compound produced in the brain, liver and kidneys by carnitine acetyltransferase. Due to its high activity, it is easily absorbed by mitochondria and provides a complete energy supply to the body, protecting vital organs from oxygen starvation. The effectiveness of the drug for restoring damage to the nervous and endocrine systems in diabetes has been experimentally confirmed.
Acetylcarnitine is involved in protein synthesis and accelerates regeneration. It has neuroprotective, antioxidant, membrane-stabilizing and neurotrophic properties. Slows down the aging process, maintaining metabolic rate at the level of a young body. Improves memory and protects the brain from the toxic effects of ammonia and glutamate.
Are there any contraindications?
"Carnicetine" - capsules, before using which you must familiarize yourself with the contraindications. However, according to experts, this drug is a biological additive and is therefore safe for human health. The only contraindication that you should pay attention to is hypersensitivity to the components that make up the medicine. Also, patients suffering from epilepsy should take the drug with extreme caution. Please note: the drug accelerates the transmission of nerve impulses, and this can lead to stimulation of damaged areas of the brain.
If you notice that the number of attacks has increased while using this medication, be sure to tell your doctor. In this case, treatment with this medication will have to be discontinued.
Composition and release form
Available in the form of white hard gelatin capsules with a yellowish powder inside. A slight odor of acetic acid is allowed.
Compound:
- Active substance – acetylcarnitine, 0.25 g per capsule.
- Additional components - microcrystalline cellulose, silicon dioxide, magnesium stearate.
- Capsule – gelatin, glycerin, methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium lauryl sulfate, titanium dioxide, water.
How to take Carnicetine tablets correctly
The price of this product is about six hundred rubles per package. Do not self-medicate even if you just want to improve your well-being and improve your performance. This is especially true for patients suffering from Alzheimer's disease. Most often, experts recommend taking one or two capsules per day. But in the most advanced cases there may be exceptions. The average duration of treatment is about one month. But, again, on the recommendation of a neurologist, the course of therapy can be extended.
Are there any side effects?
According to patient reviews, side effects occur very rarely with the use of this medicine. Some people taking Carnicetine capsules have complained of nausea, vomiting and abdominal pain. However, such symptoms disappeared very quickly with symptomatic treatment.
Also, do not forget about allergic reactions. It is possible that a rash and itching may appear over the entire surface of the body. Therefore, it is best for people prone to allergic reactions to avoid using this product.
This biological additive is not capable of influencing the management of vehicles and other means that require concentration.
"Carnicetine": analogues
In pharmacies you can find a large number of analogues of the drug “Carnicetine”. All of them are very effective, but self-medication is by no means recommended. You can buy them without a doctor's prescription, but do not forget that the unreasonable use of medications can have extremely disastrous consequences. Therefore, buy substitutes only if your doctor gives you the go-ahead.
Pay attention to products that have a similar effect on the body:
— “Actovegin”;
— “Cerebrum Compositum N”;
— “Metapictures”;
- “Elkar” and many others.
It is worth repeating once again that these medications should only be purchased on the recommendation of a doctor.
Reviews from doctors and patients
The drug "Carnicetine", the indications for use of which were described above, is a very good remedy that improves brain function and restores neurons. Doctors prescribe it very often to their patients, as good results are noticeable after the first week of use. The medicine can improve mental performance and alleviate the condition of patients suffering from Alzheimer's disease. However, you should not hope that in this case the medication will actually improve brain functionality. It will only slow down pathological processes.
"Carnicetine", reviews of which are mostly positive, appealed to the majority of patients leading an unhealthy lifestyle. The active components included in the drug are really capable of improving the condition during stress and overwork. The main thing is not to skip pills and follow the dosage prescribed by your doctor. The product also shows good results when used by elderly people. Therefore, doctors very often prescribe Carnicetine tablets to people after sixty years of age. Analogues of this remedy are also very effective, but they must be used wisely.
If you nevertheless decide that the use of Carnicetine tablets can improve your condition and improve your mood, then, with the consent of the doctor, you can safely take them.
Eat right, exercise, get plenty of rest and visit your doctor on time, and then you will not be afraid of any diseases. Be healthy and take care of yourself.
Digestibility
After oral administration, acetylcarnitine is rapidly absorbed from the small intestine by active transport or simple diffusion (when administered in high doses). Peak concentration in the blood is reached after 4 hours, the therapeutically effective amount of the drug remains in the blood for up to 8 hours. It enters cells against a concentration gradient due to energy-dependent processes. Metabolic products are excreted in the urine; when large doses of the drug enter the bloodstream, they are excreted unchanged.