Kolpotrofin: instructions for use of cream and suppositories


Candles

Price: 2000 rubles
1 candle contains:

  • Promestrien
  • E216
  • E218
  • Rubber-like substance
  • Paraffin
  • Silicon oxide
  • Polydimethylsiloxane
  • E491
  • Gelatin
  • Water.

Colpotrophin is available in the form of capsules for intravaginal administration. They look like a small egg of yellow-pearl color. Feels soft and comfortable to type. Packaged in blister packs of 10 candles. They are easily squeezed out of the packaging, without the need to cut the plate.

Includes 1 blister and instructions for use.

Mode of application

Colpotrophin in suppositories is pre-wetted for a few seconds and applied intravaginally once at night, the number of doses is as follows:

  • Restoration of the cervical mucosa – from 10 days
  • Urogenital diseases – 20 days
  • Treatment before and after surgery – from 10 to 20 days before and after the intervention
  • Preparation for the birth of a child - 5-6 days before birth and 10 days after that.

How to use Colpotrophin

Kolpotrofin suppositories are used depending on the indications:

  • When treating urogenital disorders - 1 suppository per day for 20 days. This regimen can be adjusted by the attending physician, and if necessary, maintenance treatment can be prescribed;
  • In the period after treatment of cervical erosion, to restore the integrity and elasticity of the cervical epithelium, 1 Colpotrophin suppository per day is prescribed for 10 days;
  • For pre- and postoperative preparation, 1 suppository is usually prescribed per day from 10 to 20 days before surgery and for the same period after it;
  • When preparing the cervix for childbirth - 5-6 days before birth, 1 suppository per day;
  • In the postpartum period, for the fastest healing of the cervix and vagina, take 1 Kolpotrofin suppository for 10 days.

Kolpotrofin cream, according to reviews, is usually prescribed with a frequency of application once a day (before bedtime).

When treating urogenital disorders, the cream is applied in a thin layer to the urethra, vulva and vagina and rubbed in with small massaging movements. During the first week of treatment, the medication is used once a day, in the next three weeks of therapy - once every two days.

For pre- and postoperative therapy and for healing in the postpartum period, the cream is used in the same way as Kolpotrofin suppositories.

For synechiae, Kolpotrofin, according to the instructions, should be applied once a day until they diverge.

Since the medication does not have a systemic effect, its use can be quite long.

Cases of overdose with Colpotrophin are not described in the instructions for the medication.

During pregnancy and breastfeeding

The medicine is used during gestation to prepare the cervix for childbirth. The drug is also used to heal tissue in the birth canal after the baby is born. If Colpotrofin was prescribed during other periods or for other reasons, it means that the doctor assessed all possible risks and decided that there would be more benefits from taking it. It is prohibited to use the drug on your own.

During breastfeeding, the medicine is prohibited, unless the child is switched to artificial formula.

Content

  • Characteristics of colpotrophin (promestrin) caps. vag. 10mg n20
  • Delivery of colpotrophin falkenstein
  • Doctor's review of Colpotrofin
  • Where to buy Falkenstein?
  • How to make an order?

Kolpotrofin vaginal capsules are used in gynecological practice in patients with a deficiency of the steroid hormone estrogen.

The active component of the drug is promestrin, a synthetic estrogen-like substance.

Promestrin has a local effect on the mucous membranes, namely, it protects epithelial tissues and promotes their rapid restoration and growth.

Indications.

In what cases are Kolpotrofin capsules prescribed? The drug is effective for urogenital disorders caused by estrogen deficiency.

The use of colpotrophin can eliminate dryness and itching in the vagina. Treatment with promestrin is indicated for recurrent vaginitis.

The drug can also be prescribed to restore the epithelium of the vagina and cervix after inflammatory diseases or surgery.

As pre- and postoperative therapy during surgical operations on the reproductive organs (including after removal of the ovaries).

When preparing the cervix before childbirth or to heal damage to the vagina and cervix after childbirth.

Application.

The drug is used topically - all details of the procedure are described in the instructions for Kolpotrofin.

The capsule is inserted into the vagina, usually one capsule is administered daily for 10-20 days (before childbirth - 1 capsule daily 5-6 days before birth).

Contraindications.

The main contraindication for Colpotrophin is hypersensitivity to promestrin and the presence of estrogen-dependent tumors, such as breast or endometrial cancer.

Analogs

Ovestin

Organon, Netherlands

Price: 1200 rub.

Ointment or suppositories Ovestin is an estrogen-containing drug that is used in gynecology.

Pros:

  • Works well
  • Often sold in pharmacies
  • Convenient packaging.

Minuses:

  • High price
  • May help slowly.

Divigel

Orion Corporation, Finland

Price: 600 rub.

Divigel gel is an estrogenic drug for external use, its composition is identical to endogenous human estradiol.

Pros:

  • Effective
  • Convenient release form.

Minuses:

  • High price
  • Smell of alcohol
  • Sticky consistency.

Side effects of Colpotrofin

According to reviews, Colpotrophin is in most cases well tolerated, without causing significant disorders of the body systems.

In extremely rare cases, when using it, local allergic reactions may occur, which manifest themselves as irritation and itching in the areas where the cream or suppositories are applied.

In cases of metrorrhagia during therapy with Colpotrophin, symptomatic therapy should be carried out.

Colpotrophin can be used during breastfeeding according to indications after medical consultation, however, due to the lack of reliable data on the safety of the drug for the child, it is recommended to interrupt breastfeeding during this period.

Colpotrophin

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Characteristics of Colpotrophin vaginal cream Promestrin 1% 15g

  • Active ingredient: Promestrin
  • Release form: vaginal cream

Colpotrophin belongs to the group of local hormonal drugs.

It is available in several dosage forms, including a vaginal cream.

The drug contains promestrin, which is a synthetic estrogen-like substance.

Colpotrophin does not penetrate the bloodstream and does not have a systemic hormonal effect, which explains the fairly high safety of this drug.

The drug is prescribed to patients of all ages.

Promestrin promotes rapid healing and restoration of the mucous membranes of the reproductive organs.

Indications.

Kolpotrofin vaginal cream is used in gynecological practice: for urogenital disorders (including during menopause), including urinary incontinence and pain during sexual intercourse (dyspareunia); before and after surgical operations performed intravaginally, as well as during removal of the ovaries; in the treatment of synechia - sticking together of the labia (including in pediatrics); for postpartum restoration of epithelial tissues of the vagina and perineum.

Application.

The decision on the advisability of using hormonal drugs is made by the doctor, based on an examination of the patient.

All details of the use of the drug are indicated in the attached instructions for Colpotrofin.

A small amount of cream is rubbed into the vagina, vulva and perineum.

Usually, 1 procedure is prescribed daily or once every 2 days.

The average duration of treatment is 10-20 days.

Contraindications.

Colpotrophin vaginal cream should not be used if you are hypersensitive to promestrin, or if you have cancer.

Instructions for use of the drug Kolpotrofin caps. vag. 10mg N20

Composition Dosage form Pharmacological group Pharmacological properties Pharmacokinetics Indications Contraindications Method of administration and doses Overdose Adverse reactions Storage conditions For what diseases is it used?

Compound

Active ingredient: Promestriene; 1 capsule contains promestrin 10 mg.

Excipients: sodium methylparaben (E 219), sodium propylparaben (E 217), white soft paraffin, perhydrogenated polyisobutene, sorbitan sesquioleate, colloidal silicon dioxide, purified water, gelatin, glycerin, dimethicone.

Dosage form

Vaginal soft capsules.

Pharmacological group

Simple preparations of natural and semi-synthetic estrogens.

Pharmacological properties

Promestriene is a synthetic estrogen-like agent intended for topical use, which has a local estrogenic effect on the mucous membrane of the lower parts of the urogenital tract, restoring their trophism. When administered intravaginally, it does not have a systemic effect, therefore it does not affect the endometrium, mammary glands and pituitary gland.

Promestriene exhibits a local estrogenic effect on the vaginal mucosa: it promotes the proliferation of the vaginal epithelium.

Pharmacokinetics

When used intravaginally, the capsule interacts with vaginal secretions, breaks down and its components are released. Promestriene does not accumulate in tissues, less than 1% of promestriene is absorbed, and its half-life is 24 hours. When administered intravaginally, Promestrien does not have a resorptive effect, and there are no systemic hormonal effects.

Indications

Vaginal atrophy caused by estrogen deficiency. Delayed healing of the vagina, cervix and vulva after childbirth, surgery, physical therapy.

Contraindications

— Hypersensitivity to the components of the drug.

- Diagnosed or suspected estrogen-dependent tumors (for example, breast or endometrial cancer).

— Untreated endometrial hyperplasia.

- Genital bleeding of unknown etiology.

- Venous thromboembolism, including a history (deep vein thrombosis, pulmonary embolism).

— Diagnosed thrombophilic disorders.

- Arterial thromboembolism, including a history (for example, angina, myocardial infarction).

- Severe liver disease, including a history of liver disease, until liver function tests return to normal limits.

- Porfiria.

Directions for use and doses

Insert 1 capsule (pre-moistened) deep into the vagina for 20 days. If necessary, treatment can be continued (menopause, castration, use of estrogen-progestin contraceptives).

Overdose

Given the route of administration and low resorption of promestrin, systemic overdose is unlikely.

However, an overdose may be accompanied by increased local adverse reactions (irritation, itching, burning) in the vulva area.

Adverse reactions

From the skin and subcutaneous tissue: very rarely local reactions, including irritation, itching, burning.

From the immune system: very rarely allergic reactions.

Other adverse reactions have been observed after the use of estrogen-containing drugs. Risk assessments were based on systemic exposure. It is not known whether these data apply to topical products:

- estrogen-dependent benign and malignant neoplasms, for example, endometrial cancer and breast cancer;

- deep venous thromboembolism of the lower extremities or venous thrombosis of the pelvic organs and pulmonary embolism (more often in patients receiving hormone replacement therapy than in patients not using hormones);

- myocardial infarction and stroke;

- gallbladder disease;

- disorders of the skin and subcutaneous tissues: chloasma, erythema multiforme, erythema nodosum, vascular purpura

- dementia.

Storage conditions

Store at a temperature not exceeding 25 ° C out of the reach of children.

SELF-MEDICATION CAN BE DANGEROUS TO YOUR HEALTH. ALWAYS CONSULT WITH YOUR DOCTOR.

For what diseases is it used?

  • Vaginitis/Vaginosis
  • Cervical erosions

Release form and composition

Dosage forms of Colpotrophin:

  • Soft vaginal capsules (10 pieces per package);
  • Vaginal cream 1% (15 g per tube).

The active substance is promestriene, the content of 1 capsule and 1 g of cream is 10 mg.

Additional components:

  • Capsules – perhydrogenated polyisobutene, sodium propyl parahydroxybenzoate, soft white paraffin, sodium methyl parahydroxybenzoate, anhydrous colloidal silicon oxide, dimethicone, sorbitan sesquioleate, purified water, gelatin;
  • Cream – sodium methyl parahydroxybenzoate, a mixture of di- and monoglycerides of saturated fatty acids, sodium propyl parahydroxybenzoate, polyglycol ethers of saturated fatty alcohols, decyl oleate, medium chain triglycerides, glycerin, purified water.

Doctor's review

Alexander Pichugin Doctor of the highest category,

“Kolpotrofin allows you to use it regularly and occasionally, eliminating not only the consequences of allergies, but also its causes. The first cases of using the drug can eliminate tearfulness, swelling, runny nose, relieve nasal congestion, itching on the skin and rashes, attacks of asthmatic cough and shortness of breath. If you use this remedy as a course method, you can insure yourself against allergic reactions at the peak of seasonal allergies. In addition, from the use of the product you can expect the restoration of metabolic reactions, cleansing the body of poisons and toxins, increasing immune resistance, improving well-being, and increasing performance. The certificates obtained by the drug as a result of clinical testing fully confirm its compliance.”

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