Lignarius is a dietary supplement that is included in the daily diet of women suffering from temporary disorders in the functioning of the reproductive organs. The dietary supplement is indicated for use during menopause, decreased libido, and age-related changes in the reproductive system.
According to reviews of women who were treated with this drug, Lignarius significantly improved their overall well-being. The dietary supplement helped eliminate unpleasant symptoms associated with hormonal changes in the body.
Pharmacological properties
Lignarius contains a patented lignan formula isolated from Norway spruce (Picea Abies) knots, which also contains essential oil, phytoncides, tannins and ascorbic acid.
The drug has a beneficial effect on the condition of the female body during menopause.
Scientists have found that 7-HMR (7-hydroxymatairesinol) is a new class of lignans with bioavailable phytoestrogens that have the properties of natural hormones. Lignans are precursors of estrogens (enterolactone). Under the influence of intestinal microflora they are converted into the active form of estradiol.
The drug Lignarius:
- reduces the frequency and severity of hot flashes;
- reduces irritability and mood swings;
- reduces the frequency of headaches;
- reduces the risk of developing cardiovascular diseases;
- increases sexual activity.
According to the results of foreign studies, the use of lignan 7-HMR in dietary programs helps protect hormone-dependent cells from growth-stimulating effects, thereby reducing the risk of developing tumors in the endometrium of the uterus and breast tissue.
By increasing high-density lipoproteins and decreasing low-density lipoproteins, lignans participate in the regulation of plasma cholesterol, which has a preventive effect against the development of atherosclerosis. This scientific statement was published in December 2007 in the Journal of Cardiovascular Pharmacology and Therapeutics.
In addition, 7-HMR strengthens the structure of cells, increasing their resistance to oxidation by free radicals and slowing down aging.
Pharmacodynamics
The pharmacodynamics of Lignarius appear after oral administration. When the capsule with the drug enters the intestinal cavity, the active substance of the dietary supplement is released. Partial breakdown of lignan begins in the gastrointestinal tract under the influence of beneficial bacterial microflora.
The main component of Lignarius is quickly absorbed into the intestinal walls, saturating the bloodstream, tissues of internal organs and systems. The constituent substances of the drug have high bioavailability and penetration into all body fluids.
The main half-life of the active substance and auxiliary components of the dietary supplement occurs in the liver tissues. The resulting metabolites in an amount of 95% are excreted from the woman’s body through the kidneys along with urine. The rest of the components of Lignarius are disposed of unchanged along with feces.
The dietary supplement does not create a significant load on the tissues of the liver and kidneys, and does not interfere with their functional activity. This pharmacodynamic property of the dietary supplement is due to its simple and safe biochemical formula.
Contraindications
Lignarius (reviews from women during menopause who took dietary supplements indicate its high therapeutic effectiveness) is contraindicated for use in the following cases:
- individual intolerance to the main and auxiliary components of the dietary supplement, which is expressed in attacks of allergic reactions (the appearance of a red rash on the skin, itching, swelling, bronchial spasm);
- pregnancy status;
- breastfeeding a newborn baby.
These are the main factors that exclude the possibility of taking Lignarius capsules. Depending on the condition of the organs of the reproductive system and concomitant diseases of the body, which will be established during the examination, the gynecologist may discover other contraindications to taking this dietary supplement.
What changes to expect
In addition to its positive effects on hormonal levels, Lignarius is considered a good antioxidant and anti-inflammatory compound. It helps a woman improve her well-being and slow down the aging process in the body. The following changes occur in the body after a course of treatment:
- Menopause symptoms caused by changes in compounds produced by the ovaries disappear or are significantly smoothed out. Sweating, hot flashes, pressure surges, irritability, and tearfulness go away.
- Weight gain stops and the figure does not “dissolve”, which is typical for hormonal changes in menopause.
- Due to the decrease in the activity of dehydrotestosterone, facial hair does not grow, hair falls out less, and hair grows back faster.
- The strength of cell membranes is restored, tissue damage from free radicals is reduced.
- Destructive phenomena and synthesis processes in the skin are balanced, collagen decomposes more slowly. In general, the integument is rejuvenated.
- Cells' sensitivity to glucose increases, which helps prevent the development of diabetes.
- Sexual function improves. Desire returns, vaginal dryness and microflora imbalance disappear.
- The ratio of bad and good cholesterol is maintained, and blood vessels are protected from atherosclerosis.
The drug helps to avoid the occurrence of cancer of the pelvic and breast organs, which depend on the hormonal background of a woman.
Lignarius has been studied abroad many times. It was found that during two months of use, the number of hot flashes is reduced from thirty per day to 10. The severity of their passage drops to almost zero.
A study of lignans in a British project, involving scientists from eight countries, proved that consumption of lignans significantly reduces the likelihood of cancer.
The drug is recognized as quite safe, does not cause allergies and is well accepted even in the presence of various chronic diseases.
Application
Lignarius is prescribed to women during menopause, which is accompanied by a decrease in the functional activity of the organs of the reproductive system. It is recommended to take 1 capsule of the drug 1 time per day after breakfast. Dietary supplements should be consumed at the same time, washed down with plenty of liquid (on average, at least 150-200 ml).
The minimum duration of the therapeutic course is 30 days. If necessary, taking Lignarius can be repeated after 1-2 weeks.
Before starting drug therapy, you should consult with a gynecologist, and also undergo a preliminary examination of the reproductive system organs, take a biochemical blood test to determine the level of female sex hormones. An examination of the body is recommended before starting a course of taking Lignarius and after its completion.
Side effects
Lignarius is a dietary supplement that is well tolerated by most women entering menopause. The manifestation of the main side properties of a dietary supplement may be associated with individual intolerance by the body to lignan or auxiliary components of the dietary supplement.
In this case, a woman may experience the following symptoms:
- headache and dizziness;
- the appearance of a small pink or red rash on the abdomen, lower and upper extremities, and neck;
- itching of the skin;
- urticaria and red swelling of epithelial tissues (the scale of the pathological condition of the skin depends on the degree of manifestation of the side effect);
- angioedema of the larynx (the most severe allergic reaction of the body, which can lead to death);
- loss of appetite and functional disorders in the functioning of the digestive system.
If side effects occur, you must stop further taking Lignarius, and also report the incident to your attending gynecologist or other specialist who prescribed the course of therapy with the dietary supplement.
Storage conditions and periods
Lignarius capsules should be stored in the original manufacturer's packaging away from direct sunlight. In the room where the dietary supplement is located, a stable air temperature should be maintained within +25 degrees Celsius, but not higher than the specified values.
Dietary supplements should be inaccessible to children of all age groups. Subject to the above conditions, the maximum storage period for Lignarius is 3 years. After the expiration date, taking the drug is prohibited.
Drug interactions
Lignarius does not interact chemically with any medications. Therefore, taking a dietary supplement is possible in the process of complex therapy with medications.
The only limitation concerns the simultaneous use of drugs that contain synthetic analogues of female sex hormones. Lignarius should be used instead of hormone replacement therapy, since the dietary supplement contains natural phytoestrogens.
Pharmacokinetics
Lignarius (reviews from women during menopause who took a course of taking a dietary supplement indicate the high effectiveness of the drug) is one of the few dietary supplements whose components have undergone pharmacokinetic studies in a certified laboratory.
Postmenopausal women did not receive replacement therapy, but regularly took Lignarius capsules. According to the results of the study, it was found that after 8 weeks the level of female sex hormones in the blood did not decrease significantly, since the drug saturated the body with natural phytoestrogens.
The pharmacokinetic feature of Lignarius is that after the dietary supplement enters the intestinal cavity, it is exposed to local microflora. The active substance of the drug, 7-hydroxymatairesinol, is broken down to the level of enterolactone, which is a form of estradiol.
The latter substance replenishes the deficiency of female sex hormones, reduces the frequency of hot flashes and other uncomfortable sensations associated with age-related changes in the organs of the reproductive system. Lignan does not have toxic properties, and its regular use helps not only stabilize hormonal levels, but also reduce excess body weight.
What's included
Lignarius is based on a substance belonging to the category of lignans. They have a phenolic structure and are extracted from plant cell walls. These substances can perform different functions: protect the liver, support the nervous system, fight tumors, or act as hormone analogues. The capsules of the female drug contain the substance 7-hydroxymatairesinol, which is also called 7-HMR. It is a phytoestrogen. Each tablet contains 30 mg of the active compound.
Microcrystalline cellulose was introduced as an excipient, the main purpose of which is to increase the absorption of the active compound. Cellulose is not absorbed by the body, but cleanses the intestines and nourishes the microflora. Therefore, its addition will only have a positive effect on health.
The capsule base is gelatin. It is a natural substance obtained from bovine cartilage.
Lignarius during menopause: description
Hormones are not only present in the female body. Plants also contain compounds that are similar in structure to human substances. Some, when taken, are used by the body to synthesize its own hormones, and some act as replacement therapy. The latter includes the drug that I take.
Lignarius is an effective phytoestrogen obtained from spruce. The product is natural without chemical additives. Designed for women suffering from menopausal symptoms, going through menopause or experiencing hormonal imbalance. They produce the product in Holland, which I especially like. Foreign medicines give me more trust and confidence in quality. Manufacturer: Provero Pharma.
The supplement is sold in a cardboard box that is quite flat and elongated upward. On it in the lower part there is an image of spruce needles and cones and the outline of a woman. The top half is white with green lettering. Inside are two blisters with white capsules. There are only 30 pieces, which is enough for a month of use.
Overdose
There are currently no clinically confirmed cases of overdose with Lignarius capsules. When simultaneously taking large doses of dietary supplements that do not meet the standards specified in the instructions, the following symptoms may occur:
- a disorder of the digestive system, which is accompanied by diarrhea or constipation;
- complete or partial loss of appetite;
- painful sensations in the central part of the abdomen;
- frequent urination due to the fact that the body is trying to get rid of excess amounts of estradiol;
- pain and discomfort in the right hypochondrium, which indicates a decrease in liver function;
- change in the color of urine towards darker;
- headache, unstable blood pressure;
- decreased or increased sexual desire;
- unstable psycho-emotional state, accompanied by sudden changes in mood, depressive states;
- dry mouth and a constantly present feeling of thirst;
- acute and moderate allergic reactions, which are expressed in redness of epithelial tissues, swelling, itching of the skin surface.
In case of an overdose of Lignarius, you must call an ambulance. To eliminate signs of general intoxication and restore gastrointestinal functions, a person must be given the maximum amount of warm water to drink, and then induce vomiting.
After this, the victim must take at least 10 tablets of activated carbon, 1 tbsp. l. Enterosgel sorbent or 1 sachet of Atoxil, dissolved in 200 ml of warm water. Doctors who come to the call must be informed about what sorbent drugs the person took and about an overdose of Lignarius.
