pharmachologic effect
The drug has a complex effect, which is determined by its constituent components.
Vitamin B1 has an active effect on the processes of neuromuscular regulation and is actively involved in the synthesis of the neurotransmitter acetylcholine.
Vitamin B6 helps normalize the functioning of the central nervous system and peripheral nervous system. It also takes an active part in the metabolic processes of the body. Participates in the synthesis of neurotransmitters.
Vitamin B12 helps normalize the functioning of the liver and nervous system, stimulates the process of blood clotting, metabolic processes, and takes part in the synthesis of amino acids.
Folic acid is involved in the synthesis of amino acids and nucleic acids.
Nicotinamide takes part in fat and carbohydrate metabolism, and in the processes of tissue respiration.
Side effects
The use of Pentovit can cause the development of allergies - the appearance of hives or itching on the skin.
There are reviews of Pentovit causing tachycardia or nausea, but these cases are isolated.
It is advisable to take the drug according to the instructions, otherwise an overdose of the main components may occur. An overdose of vitamin B1 threatens to impair the functioning of the kidneys and liver; a person may feel fever, cramps, and his blood pressure may drop.
Due to an excess of vitamin B6, problems with blood circulation in the legs and arms may occur.
Vitamin B9 in large quantities can cause digestive disorders, poor sleep, and increased excitability.
Due to an overdose of vitamin B12, thrombosis, pulmonary edema, and heart failure can develop.
Exceeding the dosage of vitamin PP causes hyperglycemia and increased frequency of angina attacks.
Pharmacodynamics and pharmacokinetics
Vitamin B1 (thiamine hydrochloride) is primarily absorbed in the duodenum and small intestine. Thiamine is distributed throughout all tissues. Approximately about 1 mg of thiamine is metabolized daily. Thiamine metabolites are excreted by the kidneys.
Vitamin PP (nicotinamide) is quickly absorbed into the gastrointestinal tract. It is distributed evenly throughout all tissues and organs.
Vitamin B6 (pyridoxine hydrochloride) is absorbed from the gastrointestinal tract, after which it is converted in the liver into pyridoxal phosphate, that is, into the active form of the vitamin. The final product of metabolism is 4-pyridoxylic acid, which is excreted from the body through the kidneys.
Folic acid in small doses is absorbed through absorption, and large doses through diffusion. Absorbed in the form of simple hydrolysates. Distributed in all tissues. The biotransformation and metabolism of folic acid have not yet been studied.
Vitamin B12 (cyanocobalamin) is transported to the ileum by a glycoprotein. If the vitamin enters the body in large doses, it is absorbed through simple diffusion. Vitamin metabolism is very slow. Excreted in bile .
Contraindications and side effects
The list of contraindications includes:
- childhood;
- pregnancy;
- lactation period;
- chronic pancreatitis;
- gallstones.
Attention! If necessary, the drug can be prescribed during breastfeeding after assessing the balance of risk for the newborn and benefit for the mother.
When taking multivitamins, there is a possibility of developing side effects. Most often they occur in people suffering from hypersensitivity to the components of the product.
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Possible side effects include:
- allergic reactions in the form of itching, urticaria;
- tachycardia;
- nausea.
But heart rhythm disturbances and nausea occur in isolated cases.
Pentovit is not prescribed if hypersensitivity to its components has previously been confirmed.
Indications for use
Indications for use of Pentovit are as follows:
- treatment and prevention of hypovitaminosis ;
- high need of the human body for B vitamins;
- recovery period after infectious diseases;
- prevention of stress , asthenic conditions ;
- neuralgia , polyneuritis ;
- dermatoses , dermatitis .
Indications for the use of vitamins are determined by the attending physician, depending on the characteristics of the course of the disease.
In what cases is it prescribed?
It is advisable to take vitamins in the following cases:
- for preventive and therapeutic purposes in case of lack of vitamins in the body;
- the body needs a large amount of B vitamins;
- during the recovery period after infectious diseases;
- dermatitis;
- neuralgia.
Indications for use can only be determined by a doctor who monitors the specific course of the disease.
Instructions for use of Pentovit (Method and dosage)
Pentovit vitamins should be used strictly according to the instructions if indicated. The instructions for children over 12 years of age and adults are as follows: take 2-4 tablets three times a day daily. The drug should be taken simultaneously with meals.
Your doctor will tell you how to take Pentovit for a specific disease. But you need to take vitamins for at least 3-4 weeks. How to take Pentovit in adult patients with a specific diagnosis depends on complex treatment.
special instructions
If the choice is made in favor of Pentovit vitamins, then you cannot take other vitamin preparations at the same time in order to exclude possible cases of overdose.
Do not exceed the dose indicated in the instructions.
The tablet shell contains sugar, so people with high blood sugar levels should be extremely careful and consult a doctor in advance.
Taking vitamins does not in any way affect the ability to drive a vehicle or operate other mechanisms that require increased attention.
Vitamins can be purchased at any pharmacy and are available without a doctor's prescription. Can be stored for 36 months from the date of production. It should be kept in a dry place out of direct sunlight.
You should not take Pentovit in parallel with alcoholic drinks. Otherwise, the absorption of the constituent components will be significantly reduced.
When taking the vitamin complex and biguanides simultaneously, a decrease in the absorption of cyanocobalamin may be observed. Do not use drugs that increase blood clotting together. With a long treatment course of anticonvulsants and parallel intake with vitamins, a lack of thiamine is noted.
Analogs
Level 4 ATC code matches:
Makrovit
Tetravit
Decamevit
Aerovit
Gendevit
Sana-Sol
Hexavit
Revit
Vitasharm
Pikovit Forte
Pikovit
Vetoron for children
Vetoron E
Vetoron
Undevit
Vitrum Performance
Analogs of Pentovit tablets are other vitamin complexes, of which there are a lot today. Analogs of the product can be considered Benfolipen , Neuromultivit , Pikovit , etc. All these products have similar indications for use, are good for hair, improve skin condition, etc.
Which is better: Pentovit or Neuromultivit?
Both drugs are useful for preventing stress, improving the condition of the nervous system, and improving the condition of hair and skin. Neuromultivit, unlike Pentovit, does not contain vitamin B3 and vitamin B9.
The price of Neuromultivit tablets is higher - 210-240 rubles for 20 tablets.
What are the benefits of Pentovit vitamins?
The effect of Pentovit vitamins is determined by their composition. When taking vitamins:
- the functioning of the nervous and cardiovascular systems is normalized;
- skin condition improves;
- emotional state stabilizes;
- intestinal problems go away;
- The body's resistance increases, it becomes less susceptible to the action of bacteria and viruses.
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This effect is achieved through the combined action of the components. Separate intake of thiamine, cyanocobalamin, pyridoxine and other substances will not help normalize the functioning of the neuromuscular system, improve appearance and relieve pain associated with irritation of nerve endings.
Important! A course of taking a multivitamin helps in the fight against depression, neutralizes the negative effects of stress and emotional overload on the body.
Reviews of Pentovit
Reviews from doctors about Petnovit are mostly positive; it is prescribed for many diseases, as well as for the prevention of diseases. However, it should be borne in mind that vitamin complexes are only aids in the treatment of a number of diseases. Therefore, patients leave reviews of vitamins depending on how effective the main treatment was. Positive reviews say that the vitamin complex helped cope with flaking of the skin, get rid of acne, and normalize the general condition of the nervous system. There are often positive opinions about the use of the drug after it is prescribed to children. Reviews of side effects are extremely rare.
Adverse reactions and overdose
As a result of using the medicine, the following undesirable reactions may occur:
- skin itching and rash;
- disturbed sleep;
- pain in the heart area;
- high excitability of the central nervous system;
- abnormal heartbeat;
- seizures (extremely rare).
Cases of overdose are possible. If you exceed the prescribed dose and do not follow the prescribed regimen, then hypervitaminosis may occur; the body will contain an excessive amount of B vitamins. To all this, adverse reactions may appear in a more pronounced form.
Pentovit price, where to buy
The price of Pentovit vitamins in pharmacies averages 120 - 170 rubles for 50 tablets. In Ukraine, Pentovit can be purchased at a price of 45 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Pentovit tablets p.p.o.
50 pcs. Altaivitamins JSC 119 rub. order
Pharmacy Dialogue
- Pentovit (tab. No. 50) Altaivitamins
116 RUR order
show more
Customer reviews about vitamins Pentovit
Averina Anastasia, 42 years old, Novy Urengoy
Due to sedentary work, cervical osteochondrosis developed; every day I suffered from pain, a feeling of numbness in my face and hands. On the advice of a doctor, I started taking Pentovit. Improvements became noticeable already on day 3. In the first week, I took tablets in the maximum allowable dosage - 12 pieces. per day, over time reduced the amount by 2 times.
Kotova Irina, 31 years old, Irkutsk
To reduce irritability and nervous excitability, I decided to take B vitamins. I chose the inexpensive Pentovit complex. After 4 weeks of taking the minimum recommended dose, I became much calmer, my sleep improved, and my problems with falling asleep disappeared. In addition, I noticed that my nails became stronger and began to peel less.
Application experience
Doctors, evaluating the experience of using the drug, emphasize:
- It is affordable and just as effective in comparison with imported analogues, which are much more expensive. Can be recommended to a wide range of patients.
- Effective for nervous disorders (anxiety, stress, hysterical reactions)
- Prescribed for vitamin deficiencies, injuries, stress, pain syndromes - Pentovit has a wide spectrum of action. Can be taken as a course annually.
- It can be used before preparing for pregnancy; the drug is effective.
Patients about the drug:
- “My hair has become much better. I’ve been taking Pentovit for a long time, every spring.”
- “Due to the stress, I felt very bad, then my left arm hurt and I couldn’t lift it. The doctor said that I had neuralgia and prescribed Pentovit. I then thought: these are just vitamins... But after five days of taking them, everything went away. Maybe I was just lucky?
Interaction
Pentovit is a biologically active drug. When using it together with other drugs, it is necessary to take into account how the drugs affect each other.
With medications
Simultaneous use of pentovit:
- with hypoglycemic drugs, slows down the absorption of vitamin B12;
- anti-gout medications from the colchicine group interfere with the absorption of vitamin B12;
- antibiotics of the penicillin group and oral contraceptives interfere with the absorption of vitamin B6;
- Not recommended with drugs that increase blood clotting;
- It is not advisable to take it with anticonvulsants; vitamin B9 is not absorbed.
These properties of the drug should be kept in mind when it is part of complex therapy.
With alcohol
The use of pentovit simultaneously with alcohol or with medications containing ethanol interferes with the absorption of vitamin B1, and the absorption of other components is also reduced. This cocktail puts a serious strain on the liver. Therefore, alcohol and pentovit are incompatible.
What else should you consider when taking medication?
Pentovit has a number of limitations in combination with other drugs , namely:
- Medicines containing colchicine and biguanides are not combined with vitamin B12.
- Alcohol in the blood greatly reduces the absorption of the drug, so you should avoid drinks that contain alcohol. In such cases, you should completely refrain from taking pills.
- To avoid overdose, you cannot combine taking other complexes that contain B vitamins with Pentovit.
- Medicines containing penicillin interfere with the normal absorption of B6. The same applies to oral contraceptives.
- Pentovit significantly reduces the absorption and effectiveness of drugs for Levodopa (Parkinson's) disease.
- When planning a pregnancy, the drug should be taken at least two months before conceiving a child.
- It should be stored in a dark place, the temperature of which does not exceed 25 degrees Celsius.
Patient reviews
According to surveys from various Internet resources, we can conclude that Pentovit belongs to the group of available vitamin preparations.
Many consumers note its relatively inexpensive cost compared to other complexes containing B vitamins .
In addition, a prescription is not required for its use, which is why it is so often used for the prevention and treatment of various diseases.
Most reviews indicate an improvement in the condition of the nervous system. The benefits of the vitamin complex are reduced anxiety, improved sleep and improved mood.
But they are not suitable for treating disorders such as panic attacks or neurasthenia. Pentovit can be used to relieve mild stress and eliminate nervous unrest. For example, many people use it after exams or stress.
There are very few reviews of side effects. In isolated cases, users experienced nausea and tachycardia. Some people have individual intolerance.
Some consumers note positive dynamics in radiculitis and osteochondrosis. Many people use it on the advice of friends to improve general well-being during seasonal illnesses.
Some users note the beneficial effects of Pentovit on hair, skin and nails. But there are many reviews that the drug did not bring significant changes to the condition of the hair and skin.
After analyzing opinions about the drug, we can talk about high consumer demand and generally favorable impressions of the product.
The disadvantages that consumers have witnessed are that sometimes body hair increases; to get a positive effect, you need to take several courses.
Consumer reviews of the Pentovit vitamin complex can be found at the end of the article.
Composition and release form
The combined drug Pentovit is available in the form of film-coated tablets. The approximate composition of 1 tablet includes the following substances:
- thiamine hydrochloride (B1);
- pyridoxine hydrochloride (B6);
- folic acid (B9);
- cyanocobalamin (B12);
- nicotinamide (PP).
Additional substances that make up the tablet and outer shell are sucrose, calcium stearate, magnesium hydroxycarbonate, beeswax and other components.
When taken simultaneously with magnesium sulfate, the presence of Mg in the main and auxiliary composition is considered insignificant and is not taken into account when calculating the dosage
The drug can be packaged in polymer or darkened glass jars, 50 tablets each. Contour cellular packaging (blisters) of 10 tablets are also available for sale. Each release form is accompanied by official instructions for use. Dispensed from pharmacies without a doctor's prescription. Pentovit is a relatively inexpensive medicine - its average cost is 125 rubles / 50 tablets.
Storage conditions and shelf life
Pentovit is stored in a dark, dry place, at a temperature not exceeding 25 degrees.
Shelf life, if conditions are met, is 3 years. When opening the drug, check visually whether the drug meets the requirements stated in the instructions. If the color of the tablets does not match, if they are crumbled, you should not take the medicine.
Overdose
If the instructions are violated and the daily doses are systematically exceeded, symptoms of hypervitaminosis develop, associated with an increased concentration of B vitamins in the blood. The patient complains of attacks of dizziness, signs of dyspepsia, migraines, insomnia, and feels a rush of blood to the neck and face. The heart rhythm is disturbed, numbness of the limbs appears. Treatment is symptomatic and begins with reducing the dose of Pentovit . Cases of overdose are rare in practice.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Pentovit, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Pentovit is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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