Slezin eye drops belong to the pharmacological group of drugs - artificial substitutes for tear fluid. The drug has a protective and moisturizing effect on the cornea of the eye, especially in conditions of insufficient production of its own tear fluid. It is used for the complex treatment of dry eye syndrome in adults; it is contraindicated for children and adolescents under 18 years of age. The possibility of use for pregnant and breastfeeding women is determined individually by the attending physician after analyzing the ratio of benefits for the mother to possible risks for the fetus or infant.
Compound
The composition is based on the following components: hypromellose, dextran.
Hypromellose
1 ml of solution contains 3 and 1 mg, respectively.
For better absorption and achievement of maximum therapeutic results, active chemical compounds are supplemented with:
- boric acid;
- sodium tetraborate decahydrate;
- glycerol;
- sodium chloride;
- potassium chloride;
- benzalkonium chloride;
- disodium edetate dihydrate;
- hydrochloric acid solution;
- distilled water.
Pharmacology
The properties of the ophthalmic product are identical to natural tears , therefore the polymer system, easily soluble in water, interacts harmoniously with natural tears.
Due to sufficient moisture and normal adsorption processes, the surface of the cornea becomes capable of retaining moisture.
After introducing eye drops, the chemical composition is mixed with natural tear fluid, resulting in the effect of its stability on the surface of the cornea.
A few minutes after the procedure, there is a decrease in symptomatic manifestations characteristic of “dry eye”. For 1.5-2 hours the cornea is protected from drying out.
Pharmacological group
The drug belongs to the pharmacological group of keratoprotectors, artificial tear fluid substitutes. Due to the content of active components, the drug has several pharmacological effects:
- Improvement of the properties of the surface film, which is best demonstrated in combination with natural tear fluid.
- Ensuring sufficient hydrophilicity of the cornea due to absorption processes at the interface between the film and the surface of epithelial cells.
Due to its pharmacological action, the drug helps to reduce the severity of irritation of the cornea and conjunctiva in conditions of insufficient production of tear fluid. After a single eye drop, the therapeutic effect lasts on average for 1.5 hours.
Systemic adsorption of the active components of the drug is extremely low; they are practically not absorbed into the blood.
Price
The ophthalmic product is available to buy without a prescription.
The cost of one bottle with a capacity of 15 ml is 172-194 rubles .
The drug is presented in a network of large pharmacies, pharmacy kiosks and online stores.
You can learn more about the methods of using eye drops and special instructions in the radar system.
special instructions
Before you start using eye drops, it is important to pay attention to the following few special instructions:
- The medicine is intended only for instillation into the conjunctival sac. The use of the solution for parenteral injection is excluded.
- It is permissible to use the medicine in case of increased dryness of the eyes due to prolonged work at the computer, exposure to bright light, overwork, irritation caused by air conditioning.
- If the patient’s well-being worsens or there is no improvement within 72 hours, the use of the medicine should be stopped and consult a medical specialist for advice.
- An auxiliary compound of the drug is the preservative benzalkonium chloride, which has a negative effect on soft contact lenses, so they should be removed before instilling eye drops. Reinstallation is allowed no earlier than after 15 minutes.
- The active and auxiliary components of the drug do not directly affect the functional state of the cerebral cortex and other structures of the central nervous system.
- In most cases, immediately after instillation of the drug, blurred vision develops, so it is not recommended to perform potentially dangerous work (driving a car) for 15 minutes.
Indications for use
An ophthalmic solution is recommended for instillation into the organ of vision if there are signs of dry eye syndrome.
This effect often occurs due to the influence of the following factors:
- smoke;
- dustiness;
- ultraviolet glow;
- dry heat;
- gusty wind;
- sudden change in temperature conditions;
- drafts, etc.
The syndrome can also be triggered by prolonged exposure to a computer monitor and frequent use of modern gadgets.
Instructions for use
The medicinal solution is intended for local use.
As unpleasant symptoms characteristic of dry eye syndrome appear, liquid is injected 1-2 drops into the conjunctival sac.
Rules for the procedure:
- wash your hands with detergent, treat all objects used during instillation with an antiseptic;
- if there are dried crusts, you need to carefully wipe your eyes with a cotton pad previously soaked in an antiseptic solution (this can be a ready-made product or a prepared decoction of chamomile or other medicinal herbs);
- take a comfortable position, taking a “sitting” or “reclining” position, throw back your head;
- pull back the lower eyelid with the fingers of one hand, inject medicine (1-2 drops) from the dropper with the other, pointing the tip of the bottle towards the outer corner of the eye;
- make several circular movements with the pupil to distribute the solution evenly;
- Use your index finger to block the lacrimal opening and hold it in this position for 30-40 seconds.
Applications and dosages
Eye drops are intended for instillation into the lower conjunctival sac. Before performing the procedure, the head is tilted back, the lower eyelid is pulled back with the finger of one hand, and the eye is instilled with the other hand using a dropper bottle, which is placed upside down. It is important to ensure that the tip of the bottle does not touch the mucous membrane of the conjunctiva, the surface of the cornea or sclera, as this can lead to mechanical damage or infection of the tissue.
for adults
The average recommended therapeutic dose is 1-2 drops, which are instilled into the conjunctival sac as needed to reduce the severity of dry eye syndrome. The duration of the course of therapy is determined by the disappearance of negative manifestations. It can be set individually by the attending physician.
for children
The medicine is not intended for use in pediatric practice.
for pregnant women and during lactation
The dosage and regimen of use of the drug are determined by the attending physician individually according to strict medical indications.
Possibility of use during pregnancy and lactation
The active components of the composition (dextran-70 and hypromellose) create protection for the anterior surface of the eyeball without showing chemical activity.
When used topically, there is no absorption of drug substances into the circulatory system, which eliminates the negative impact on reproductive function and the process of fetal development. These factors are a guarantee of safety if the need for the drug Slesin arises to eliminate an ophthalmological problem.
Despite the lack of studies of the drug on the penetration of active substances into breast milk, it is prescribed during lactation, which is due to the properties of the active ingredients and the lack of ability to be absorbed into the circulatory system.
SLEZIN (drops)
The almologist offered me a few more unknown ones, some of which I purchased.
This time I decided to try drops that are significantly cheaper than Systane Ultra drops, which I most often use. I purchased these Slezin drops:
The packaging is quite ordinary, inside is a dropper containing drops and instructions for use.
Dropper volume 15 ml. Regular medium volume. No more is needed, because Slesin must be used within 4 weeks after opening the bottle.
The active components of the drug are hypromellose and dextran, the combination of which produces artificial tears that help moisturize the cornea.
After a single use, the effect of the drug lasts for 90 minutes. The drug can be instilled as needed.
Contraindications: hypersensitivity to the active substances of the drug and age under 18 years.
Storage is quite standard - at a temperature not exceeding 25 degrees.
Drops cannot be used on LENSES! For those who use them, I think this will be a significant limitation. Not relevant for me.
Quite standard drops, without any special complaints regarding use and storage.
In the annotation, I was a little amused by one phrase regarding use during pregnancy: ADEQUATE and strictly controlled clinical studies on the safety and effectiveness of the drug during pregnancy and lactation have not been conducted.
MAYBE it would have been easier to write that no research was done AT ALL? Otherwise there was a residue that only INADEQUATE ones were carried out.
After using the drops for 2 weeks, I can safely advise you to consider them as an alternative to your usual drops, or just for a trial to change the drug.
Supplement after use for a month:
There is almost half a bottle left, a third for sure, it feels like it. Advice to the manufacturer is to reduce the volume and cost of the drops. Well, in addition, I give my selection of moisturizing eye drops:
*** CAN BE USED WITH LENSES: blink, hilozar-chest of drawers, hilomax-chest of drawers, hilo-chest of drawers, lens-chest of drawers, view-chest of drawers, hilabak, artelak-splash, artelak-balance, systain-ultra.
*** CANNOT BE USED WITH LENSES: lacrisify, optiv, lacropos, carbomer, oftagel, hypromelose-P, ophtolik, pure tear, slezin, natural tear.
I hope you find something for yourself!
Lately I've been using other drops. Reason: tears contain a substance that provokes even greater dryness in the future. Therefore, my favorite now are more expensive drops: Santen “Oxial” moisturizing ophthalmic solution - I found the ideal drops for the eyes.
However, drops alone are not enough for me. Once every 3-4 months I take a course of lutein. I bought this one on iHerb, I liked it: Jarrow Formulas Lutein dietary supplement - Everyone who works at a computer needs such courses!
If your eyes need emergency help - you need to nourish and strengthen the blood vessels, I advise you to read about emoxypine: Moscow Endocrine Eye Drops - 2 application regimens + results after a course of treatment.
I'll update the review in a few months. At my next appointment with the ophthalmologist, I was given a recommendation to ensure that when using drops, they do not contain a substance such as benzalkonium chloride. It provokes even greater dryness after use and forces you to use drops continuously. It's in the teardrop. Therefore, I lower the rating to 3. And I do not recommend it, as you understand. I recommend Oksial. It is more expensive, but it is a new generation drug with hyaluronic acid. A very comfortable product. The best I've tried so far.
Side effect
When testing the ophthalmic agent, side effects from various body systems were identified, which is expressed in the following symptoms:
- allergic reaction;
- headache;
- irritation of the mucous membrane of the eye, burning, itching, the effect of the presence of sand, excessive tearing, the formation of crusts along the edge of the eyelid, swelling.
The most common effect is blurred vision . The duration of the side effect ranges from several minutes to 1-2 hours. Sharpness and clarity are restored spontaneously.
Discomfort on the skin around the eyes is less common.
Precautionary measures
When using Slezin, it is important to adhere to the following rules:
- It is unacceptable to inject the medicine or take it orally.
- After administration of the drug, side effects may occur. They usually disappear spontaneously after 1-2 days. If symptoms persist for up to 3 days, you should inform your doctor. He will select a suitable substitute.
- While using eye drops, it is recommended not to wear lenses due to the effects of benzalkonium chloride included in the drug. The substance causes eye irritation and can change the color of the optics, especially if they are made of soft material. Hard lenses should be put on 15-20 minutes after instillation.
- Upon contact with mucous membranes, the product can cause blurred vision, so starting work or driving a car is allowed only after complete restoration of clarity.
- It is unacceptable to use expired medicine for treatment. In addition to a decrease in the therapeutic effect, the risk of complications increases.
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- Carsil Dragee
- Ascorutin Oral tablets
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- Ergoferon () Lozenges
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- Omez Capsule
- Papaverine Oral tablets
** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Slesin, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Slesin is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Reviews
Andrey, 45 years old:
I have been working on truck cranes for over 20 years. Irregular working hours provoke severe eye fatigue at the end of the shift; pain and the presence of sand are felt. Three years ago, on the advice of a doctor living next door, my wife bought Slesin drops. Now I periodically use them when discomfort and unpleasant sensations occur. The active ingredients of the medicine act from the first minutes after use. I'm quite pleased with the result.
Veronica, 28 years old:
An inexpensive and completely safe remedy for itchy eyes, dryness and itching. Student life abruptly turned into family life with all the hardships of everyday life. Sleepless nights and overexertion cause dysfunction of the lacrimal glands, resulting in itching, irritation, and crusting along the edges of the eyelids. I compensate for the lack of natural tears with Slezin eye drops, which are distinguished by their safe composition and mild effect. 2-3 day procedures are enough to eliminate problems.
Analogs
If there are contraindications or for a number of other reasons, Slesin can be replaced with another drug.
Among the most effective:
- Natural tears (Alkon, USA) – 380 rubles;
- Aistil (S.I.F.I. S.p.A., Italy) – 256 rubles;
- Lakrisifi (S.I.F.I. S.p.A., Italy) – 285 rubles;
- Balarpan (Eye microsurgery NEP, Russia) – 431 rub.
Cheaper analogues are also available in pharmacies.
Among the popular ones:
- Taurine (FP update, Russia) – 14 rubles;
- Hyphenleuse (Sintez AKOMP, Russia) – 53 rubles;
- Emoxy Optic (Sintez, Russia) – 47 rubles;
- Vidisik (Dr. Gerhard Mann, Germany) – 130 rub.
You should not choose a substitute yourself, as you can negate the therapeutic effect.
Only a specialist, based on his experience and the condition of the eye tissues, will be able to correctly adjust therapy to quickly eliminate ophthalmological problems.
