Okumetil eye drops: instructions for use and what they are needed for, price, reviews, analogues

Description and composition

The ophthalmic solution contains several active compounds (the content is indicated in 1 ml):

• Diphenhydramine hydrochloride – 10 mg.
• Zinc sulfate – 10 mg.
• Naphazoline hydrochloride – 10 mg.

The drug also contains the following auxiliary components:

• Lemon acid.
• Methylene blue dye.
• Hypromellose 4000.
• Sodium citrate.
• Sodium hydroxide.
• Benzalkonium chloride.
• Sodium chloride.
• Sterile distilled water.

Description of the drug

The medicine is a clear blue liquid packed in a plastic bottle equipped with a dropper. The bottle volume can be in 2 variations: 5 and 10 ml.
Each bottle is in a cardboard box and is supplied with detailed instructions. Country of origin: Egypt (Alexandria). The drug contains 3 types of active substance: zinc sulfate, diphenhydramine hydrochloride and naphazoline hydrochloride. Each type of active ingredient is contained in the drug in the same concentration: 10 mg in a volume of 10 ml of medicine.

During long-term storage, Okumetil eye drops require conditions characteristic of almost all medications: t within +15 +25˚С, inaccessibility to direct sunlight. If the requirements are met, the medicine retains its properties for 3 years from the date of manufacture, after opening - no longer than 4 weeks.

Pharmacological group

The drug represents the pharmacological group of antihistamines, antiallergic ophthalmic drugs. The pharmacological effect of the drug is due to the presence of a combination of active components:

• Naphazoline is a sympathomimetic compound that has a pronounced vasoconstrictor effect, developing quite quickly in the tissues. When applied locally, the result is a reduction in the severity of edema and hyperemia of the mucous membrane.
• Zinc sulfate – has a drying, astringent, antiseptic and anti-inflammatory pharmacological effect on the mucous membrane when the drug is applied locally.
• Diphenhydramine is a compound that blocks H1-histamine receptors. It has an antiallergic effect, as it suppresses the tissue reaction to the influence of the main mediator of the inflammatory reaction, histamine. Due to this, it reduces swelling and reduces the permeability of microcirculatory vessels.

In general, the drug has an anti-inflammatory, antiallergic and antiseptic therapeutic effect.

After instillation of the ophthalmic solution into the eyes, the active components undergo local adsorption in the tissues. They partially penetrate into the blood.

Okumetil

Name: Ocumethyl Pharmacological action: The combination of active ingredients of the drug is represented by a blocker of H1-histamine receptors, a sympathomimetic and a zinc salt. The histamine receptor blocker, due to its specific effect on H1 type histamine receptors, helps reduce pathological swelling and relieve an allergic reaction.

The sympathomimetic has a fairly strong vasoconstrictor effect, due to this the hyperemia of the eye is relieved, and the increased permeability of the blood vessels of the eye is eliminated. Zinc sulfate has an antiseptic effect, helps relieve local inflammation, and helps eliminate swelling.

Indications for use: The drug Okumetil is indicated for use in: - acute atopic conjunctivitis; — chronic conjunctivitis; - blepharoconjunctivitis; - eye discomfort; - eye irritation; - angular conjunctivitis.

Directions for use: Standard dosage: 1 drop/2-3 times/day. The absence of an observed effect after 72 hours of use is an indication for discontinuation of the drug.

Side effects: The use of drops may be accompanied by: - ​​conjunctival hyperemia; - local burning; - pupil dilation; - ataxia; — deterioration of vision; - headache; - dizziness; - central scotoma; — maculopathy; - tachycardia; - dryness of the mucous membranes of the eyes; - nausea; - increased blood pressure.

Contraindications: The drug Okumetil is not indicated for: - hypersensitivity to the active components; - IHD; - hypersensitivity to the auxiliary components of the drops; - arterial hypertension; - severe atherosclerosis; - pregnancy; - angle-closure glaucoma; - lactation; - stenosing gastric ulcer; - epilepsy; — indications in patients under 24 months of age; - bronchial asthma; - stenosis of the bladder neck; - pheochromocytoma; — prostate hyperplasia; - diabetes mellitus; — dry eye syndrome; - hyperfunction of the thyroid gland.

Pregnancy: The drug Okumetil is not prescribed to pregnant women.

Interaction with other drugs:

Overdose: Due to the relatively low systemic absorption of the active ingredients from this dosage form, overdose is unlikely.

Release form: The drug Okumetil is available in the form of eye drops. The packaging is as follows: - 5 ml solution/bottle/packaging; — 10 ml solution/bottle/package.

Storage conditions: Storage temperature of Okumetil drops is 15-25 degrees Celsius. The shelf life of a sealed bottle is 3 years. The shelf life of an opened bottle is 1 month.

Composition: 1 ml drops Okumetil contains diphenhydramine hydrochloride 0.01 g, naphazoline hydrochloride 0.01 g, zinc sulfate 0.01 g. Auxiliary components: sodium hydroxide, sterile water, sodium chloride, citric acid, sodium citrate, hypromellose 4000, benzalkonium chloride, methylene blue.

Additionally: The opened bottle must close well after use. When using, do not allow contact with the mucous membranes of the eyes, skin, or hands, so as not to provoke contamination of the solution.

You should not drive a car for 15 minutes after using the drops due to a possible decrease in visual acuity.

Attention! The description of the drug " Okumetil " on this page is a simplified and expanded version of the official instructions for use. Before purchasing or using the drug, you should consult your doctor and read the instructions approved by the manufacturer. Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Indications for use

The medicine is prescribed for the complex treatment of specific inflammatory reactions in the structures of the eye, which are predominantly of allergic origin.

for adults

There are several main medical indications for which the drug is used:

• Conjunctivitis and blepharoconjunctivitis, which are allergic in origin.
• Reducing the severity of manifestations of irritation of eye tissues, which include hyperemia (redness) of the conjunctiva, burning, and foreign body sensation.
• Nonspecific conjunctivitis and blepharoconjunctivitis, which have a chronic course.
• Angular conjunctivitis.

for children

The medication can be prescribed to children over 2 years of age for the same medical reasons.

for pregnant women and during lactation

The drug is contraindicated.

Contraindications

There are a number of pathological and physiological conditions of the human body in which the use of medications is contraindicated:

• Angle-closure glaucoma.
• Pregnancy at any stage and lactation period.
• Ulcer of the stomach or duodenum, which is accompanied by the development of stenosis.
• Bronchial asthma.
• Cardiovascular pathology, including coronary disease, arterial hypertension.
• Increased functional activity of the thyroid gland.
• Severe atherosclerosis of arterial vessels.
• Individual intolerance to the components of the drug.
• Dry eye syndrome.
• Prostatic hyperplasia in men.
• Bladder neck stenosis.
• Epilepsy.
• Pheochromocytoma.
• Diabetes.
• Children's age less than 2 years.

The drug should be used with caution in patients taking drugs from the monoamine oxidase enzyme inhibitors (MAO) group, as well as any drugs that increase systemic blood pressure.

Indications and contraindications

Eye drops are used for irritation and discomfort of the eyes that are allergic or inflammatory in nature.

Indications for the use of Okumetil are the following pathological conditions:

• Angular conjunctivitis . The second name of the disease is diplobacillary conjunctivitis. The causative agent is the diplobacillus Morax-Axenfeld, the peculiarity of which is adaptation to low temperatures. Therefore, infection can occur at any time of the year and be accompanied by increased discomfort and even microcracks in the corners of the eye;
• Allergic conjunctivitis . It can be a concomitant symptom of a severe allergy that spreads to the respiratory system (rhinitis, sneezing, coughing) and even the skin. Sometimes the irritating effect extends to the eyelids - in this case, allergic blepharoconjunctivitis occurs;
• Nonspecific conjunctivitis . Most often, such irritation develops against the background of activation of staphylococcal microflora under the influence of accompanying factors: prolonged exposure to irritants (dust, dirt, chemicals), metabolic disorders, eyelid diseases (blepharitis, meibomitis), bacterial infections of the nasal cavity;
• Chronic blepharoconjunctivitis . If conjunctivitis is untimely or incorrectly treated due to weakening of local immunity, the edges of the eyelids become infected and concomitant blepharitis develops. Since the process of treating complex inflammation is quite complex, the disease often progresses to a chronic stage. The causative agents in this case can be bacteria (staphylococci, streptococci, moraxella, chlamydia, etc.), viruses (herpes, adenovirus), and Demodex mites.

Okumetil eye drops can also be used to prevent these diseases, with the very initial manifestations of discomfort: itching, burning, irritation, etc.

Contraindications

Since the Drug has a systemic effect on the body when absorbed, the list of contraindications for its use is quite extensive. It includes the following states:

• Individual intolerance to the components of the drug;
• Diseases of the heart and blood vessels;
• Bronchial asthma, epilepsy, diabetes mellitus;
• Dry eye syndrome and angle-closure glaucoma;
• Pheochromocytoma is a hormonally active tumor characterized by increased production of adrenaline or norepinephrine;
• Prostate hyperplasia (in other words, prostate adenoma);
• Stenosing gastric ulcer – located in the pyloric part of the stomach and, when scarred, makes it difficult to evacuate food;
• Bladder stenosis (Marion's disease) – hypertrophy of muscle cells in the walls of the bladder, resulting in impaired patency of the urethra;
• Enhanced thyroid function.

That is why, even for preventive purposes, the drug can only be used after consultation with an ophthalmologist.

During pregnancy

Not all drops have a pronounced systemic effect, but Okumetil is one of such drugs. The long list of its contraindications indicates that this effect on the body is far from harmless. But during pregnancy (especially in the 1st trimester), any negative impact can have the same effect on the fetus.
The official instructions are categorically against the use of the drug during the period of bearing and feeding a child, although some other materials indicate a reference to the lack of study of the drug. An additional argument in favor of the ban is the fact that the composition contains a vasoconstrictor, which, if used incorrectly, can cause a number of negative health consequences.

Long-term wear contact lenses

This article will tell you how to choose lenses for your eyes.

Are colored lenses harmful? https://eyesdocs.ru/linzy/karnavalnye/cvetnye-kontaktnye-linzy-vredny-ili-bezopasny.html

For small children

When treating young children, the use of Okumetil is permitted only from 2 years of age. The drug has many contraindications, and the vasoconstrictor in the composition can cause addiction if used uncontrolled.

The dose for the treatment of children does not differ from that for adults and is 1 drop 2-3 times a day. The duration of treatment when using drugs with a vasoconstrictor should not exceed 5 days, since it only alleviates the symptoms and can cause the development of allergic reactions.

If your baby has an allergic reaction, you should not self-medicate based only on official instructions. After all, there are a number of other factors, the main one of which is the individual characteristics of the child’s health. And only a qualified specialist can take into account all the necessary components when prescribing a medicinal drug.

Applications and dosages

Eye drops are instilled into the lower conjunctival sac. To do this, the lower eyelid is pulled back with a finger, the head is tilted back a little, and the ophthalmic solution is instilled with the other hand using a dropper bottle. In this case, it is important to ensure that the tip of the dropper bottle does not touch the surface of the eye structures, as this can cause mechanical damage or infection of the structures.

for adults

The average recommended dose is 1 drop, which is instilled into the lower conjunctival sac 2-3 times a day. The duration of therapy is determined by the attending physician individually. If improvement does not occur within 72 hours, then discontinuation of the drug and re-examination by a medical specialist is required.

for children

The dosage does not differ significantly; it is usually 1 drop into the conjunctival sac of the eye affected by the pathological process 2 times a day.

for pregnant women and during lactation

Medication is contraindicated for use.

Side effects

After starting to use the ophthalmic solution, the following local negative reactions may develop:

• Blurred vision.
• The appearance of a burning sensation, a feeling of “sand” in the eyes.
• Maculopathy in the presence of concomitant aphakia in the patient.
• The appearance of a central scotoma.
• Swelling of the mucous membrane of the eyes, hyperemia, pupil dilation, increased intraocular pressure, which are caused by the presence of naphazoline in the drug.
• Paresis of accommodation.

Somewhat less frequently, systemic side effects may develop due to the absorption of the active components of the drug into the blood:

• Tachycardia.
• Increased systemic blood pressure.
• Headache.
• Nausea.
• Drowsiness.
• Weakness.
• Decreased speed of psychomotor reactions.
• Dizziness.
• Impaired coordination of movements.

Possible complications caused by the drug

When treated with Okumetil eye drops, the most common allergic reaction that occurs is a burning sensation on the surface of the conjunctiva. Other undesirable effects include reactive hyperemia, pupil dilation, and increased intraocular pressure. All these symptoms are a consequence of the presence of a vasoconstrictor in the composition and are a reason to stop treatment and then consult a doctor.

Side effects that develop much less frequently include:

• Heart rhythm failure;
• Increased blood pressure;
• Dizziness, disruption of the vestibular apparatus;
• Drying of the mucous membrane of the eye, numbness;
• Development of photophobia.

Any of these conditions that occur after using the drops indicates a negative systemic effect and requires immediate discontinuation of treatment.

The drug may affect the action of some systemic drugs, enhancing or weakening the effect of their use. Therefore, before using the medicine, you should carefully study the instructions and consult a doctor.

Okapin eye drops

Eye drops for newborns are described in this article.

Causes of constricted pupils https://eyesdocs.ru/zabolevaniya/anizokoriya/pochemu-proisxodit-suzhenie-zrachkov.html

Interaction with other drugs

The active components of the ophthalmic solution, when used simultaneously, can interact with drugs of other pharmacological groups, therefore, before starting to use the drug, it is important to consider the following features:

• Strengthening the therapeutic effect of MAO inhibitors, beta-blockers, adrenergic agonists.
• Slowing down the adsorption of anesthetics for local use.
• Reducing the effects of diphenhydramine and central nervous system stimulants.
• Zinc sulfate, which is part of eye drops, is incompatible with lead, silver, quinine, citral, and ichthyol salts.

If it is necessary to simultaneously use several ophthalmic drugs, the period of time between installation in the eyes should be at least 15 minutes.

special instructions

Before you start using the ophthalmic solution, it is important to pay attention to several precautions:

• To avoid contamination of the solution and subsequent infection of the eye, it is important not to touch the tip of the dropper bottle to surrounding objects.
• The ophthalmic solution contains the preservative benzalkonium chloride, which has a negative effect on the condition of contact lenses. It is recommended to remove eye drops before instilling them. Reinstallation is allowed no earlier than after 15 minutes.
• Immediately after eye drops, vision may become blurred, so potentially dangerous work can be performed no earlier than 15 minutes later.
• Activities that require sufficient concentration and speed of psychomotor reactions must be careful, since the use of eye drops cannot exclude their influence on the functional state of the structures of the central nervous system.

Analogs

Montevisin

A drug that has a similar therapeutic effect. It contains tetrizoline. When applied locally, the drug has a vasoconstrictor effect and helps reduce the severity of swelling of the mucous membrane. The drug is presented in the dosage form of eye drops. It is used to treat inflammatory and allergic eye pathologies in adults and children over 6 years of age. The medicine is contraindicated for pregnant and breastfeeding women.

Visoptic

Eye drops that contain tetrizoline and have a decongestant therapeutic effect. They are designed to reduce the severity of irritation, inflammation and allergic reactions of the eyes. The drug is intended for adults and children over 3 years of age. It is permissible to prescribe eye drops during pregnancy and breastfeeding if the expected benefit to the mother outweighs the potential risks to the fetus.

Visine

A medication that has an anti-edematous effect due to local vasoconstriction in the mucous membrane. It is available in the dosage form of eye drops and contains tetrizoline. The drug can be prescribed to adults and children over 2 years of age for the complex treatment of inflammatory and allergic eye pathologies. Data on the possibility of using the drug during pregnancy and lactation are not provided.

conclusions

Okumetil eye drops are a drug effective for a number of allergic diseases and other pathologies associated with irritation of eye tissue.

The drug has a number of contraindications, since it is absorbed into the systemic bloodstream and affects the condition of the body as a whole. Therefore, the use of the drug must be agreed with a qualified specialist and used in treatment only after its official prescription.

It will be useful to know about the methods of using drugs such as Alcaine and Cipropharm.