In case of intoxication of the body caused by infections or viruses, alcohol overdose, long-term use of potent medications, a Reamberin drip is often prescribed. The drug is produced on the basis of sodium succinate and regulates cellular processes, stabilizing energy metabolism and the body’s ability to cleanse itself.
Pharmacodynamics and pharmacokinetics
The active substance protects the heart muscle, nerve cells, liver and kidneys from toxins . It also has antihypoxic, antioxidant and detoxification activity. By inhibiting the reactions of fat peroxidation , during hypoxia and ischemia antioxidant are stimulated .
The membranes of brain , kidney, liver and heart are stabilized The product also has a diuretic effect.
Sodium N-methylammonium succinate penetrates cell mitochondria and participates in the Krebs Cycle , inhibiting oxidation reactions and increasing intracellular energy potential ( creatine phosphate and adenosine triphosphate ).
Penetrating into the body, the drug does not accumulate, but is completely consumed.
Contraindications to the use of droppers
The medicine has a wide therapeutic effect and beneficial properties, so if used correctly, the patient will only benefit from Reamberin. There are not many contraindications for the solution, however, it is worth considering that the drug is prohibited for use by patients with individual intolerance to the main or auxiliary components.
Other restrictions for infusions:
- complications of TBI;
- impairment of all kidney functions;
- an increase in blood pH due to the accumulation of an alkaline substance;
- period of infancy - until the child reaches 12 months.
Reamberin is prescribed to pregnant women with caution due to the penetration of the active substance through the placental barrier. However, to prevent placental insufficiency in case of infectious and viral lesions of the body, some doctors practice prescribing the drug in order to avoid deviations in the development of the fetus.
There have been no large-scale studies on women during pregnancy, so the decision to prescribe a detoxifying agent remains with the treating doctor. Scientists say that the drug does not pose a threat. The injection is permitted if the expected benefit to the mother outweighs the potential risk to the baby.
WE RECOMMEND THE ARTICLE!
Ringer's solution normalizes the electrolyte background and is often used for emergency care. Read more >>
The medication is contraindicated for nursing mothers due to insufficient research. If it is necessary to use Reamberin during lactation, you must avoid breastfeeding.
Instructions for use of Reamberin (Method and dosage)
Depending on the severity of the patient’s condition, different rates of administration and daily dosages are prescribed.
Instructions for use of Reamberin for alcohol intoxication : the drug is administered intravenously , the injection rate is 90 drops per minute. The daily dose is 400-800 ml.
For children, an IV is placed based on the principle of 8 ml of the drug per kilogram of the patient’s weight. The maximum amount of Reamberin is 400 ml per day.
The course of treatment is no more than 11 days.
Indications
Reamberin is prescribed to stabilize patients suffering from intoxication or hypoxia caused by external or internal factors of any etiology.
For psoriasis, the solution helps to more fully and deeply absorb the active components of medications prescribed to the patient as the main treatment, and accelerate the elimination of toxic substances from the body.
This contributes to:
- reducing redness of the skin;
- disappearance of peeling;
- reducing the area of psoriatic plaques.
Treatment can be carried out both in the stage of exacerbation of the pathology to achieve a faster clinical effect from the prescribed therapy, and during the period of remission to prevent relapse.
Analogs
Level 4 ATC code matches:
Calcium Chloride
Calcium chloride
Magnesium sulfate
Sodium chloride
Potassium Chloride
Rheosorbilact
Analogues of the product are: xylate, potassium chloride, glyxyl, calcium chloride, lactoxyl, magnesium sulfate, sodium bicarbonate, sodium bicarbonate, sodium chloride, plerigo .
Side effect
According to the World Health Organization, adverse effects are classified according to their frequency as follows:
– very frequent (≥ 1/10); – common (from ≥ 1/100 to – infrequent (from ≥ 1/1000 to – rare (from ≥ 1/10000 to – very rare ( – frequency unknown (cannot be determined based on available data).
If the drug is administered quickly, undesirable effects are possible.
General disorders and disorders at the injection site: very rarely - hyperthermia, chills, sweating, weakness, pain at the injection site, edema, hyperemia, phlebitis. Immune system disorders: very rarely - allergic reactions, angioedema, anaphylactic shock. Disorders of the skin and subcutaneous tissues: very rarely - allergic rash, urticaria, itching. Disorders of the respiratory system, chest and mediastinal organs: very rarely - shortness of breath, dry cough. Cardiac disorders: very rarely - tachycardia, palpitations, shortness of breath, pain in the heart, chest pain. Vascular disorders: very rarely - arterial hypotension/hypertension, short-term reactions in the form of a burning sensation and redness of the upper body. Gastrointestinal disorders: very rarely - nausea, vomiting, metallic taste in the mouth, abdominal pain, diarrhea. Nervous system disorders: very rarely - dizziness, headache, convulsions, tremor, paresthesia, agitation, anxiety. To avoid unwanted effects, it is recommended to adhere to the dosage regimen and rate of administration of the drug. If adverse reactions occur, it is recommended to reduce the rate of drug administration. If any of the undesirable effects indicated in the instructions get worse or you notice any other undesirable effects not listed in the instructions, tell your doctor.
Reviews of Reamberin
Reviews about Reamberin are good. The drug copes well with the task of freeing the body from toxins and rehabilitation after severe infectious diseases. In itself, while not being a panacea for any specific disease, the medicine significantly speeds up the healing process. Sometimes side effects occur, and therefore the drug is not recommended for use outside the hospital.
Reviews of Reamberin for psoriasis : The use of the drug in the treatment of this disease is a controversial issue, but some experts prescribe the drug in order to free the body of toxins, improve metabolic processes, improve liver function and, as a result, cure a person of psoriasis. With long-term use in courses, under the supervision of an experienced doctor, the medicine gives good results.
Chemical composition of the drug
The main active ingredient of Reamberin, a detoxification agent for infusion therapy, is meglumine sodium succinate.
With the help of detoxification, you can cleanse the body of toxic lesions.
The medicine also includes:
- calcium, sodium, potassium salts;
- caustic soda;
- distilled water.
Reamberin is a solution for parenteral use, administered mainly into a vein using a dropper. Thanks to intravenous administration, the medicine is quickly processed and completely eliminated from the human body.
The drug is a colorless, fragrance-free liquid, dispensed by pharmacists by prescription, packaged in glass bottles of 100, 200, 250, 400 and 500 ml. The detoxifying medicine is also bottled in polypropylene jars of 250 and 500 ml, but plastic packaging is used only in hospital settings.
Reamberin price, where to buy
The price of Reamberin in 1.5% packages is about 142 rubles per 250 ml.
The cost of 500 ml of the drug with the same dosage is 162 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Reamberin solution for inf.
1.5% 500ml (polymer container) No. 5OOO NTFF POLYSAN 855 rub. order
Pharmacy Dialogue
- Reamberin (vial 1.5% 400ml) Polisan NTFF
RUB 226 order
- Reamberin (vial 1.5% 200ml) Polisan NTFF
RUB 196 order
show more
Pharmacy24
- Reamberin 1.5% 200 ml solution for infusion TOV NTFF Polisan, Russian Federation
74 UAH order - Reamberin 1.5% 400 ml TOV NTFF Polisan, Russian Federation
92 UAH order
PaniPharmacy
- Reamberin infusion Reamberin solution inf. 200ml Russia, Polisan
96 UAH order
- Reamberin infusion Reamberin solution inf. 400ml Russia, Polisan
103 UAH order
show more
Meglumine sodium succinate
The pharmacokinetics of the drug is based on the formation of the following biological processes in the body:
- Antihypoxic - when a normal amount of oxygen enters the internal organs and soft tissues of the brain.
- Antioxidant - leads to a decrease in the number of harmful radicals, removes toxins, alcoholic barbiturate from the body, restores the internal structure of cells.
Thanks to these properties, Reamberin helps replenish energy reserves, normalize biochemical reactions, increase the body’s ability to quickly process glucose and utilize adipose tissue, normalize the blood formula, and also improve the acid-base and water balance of the body. In addition, the injection solution gives a weak diuretic effect. The drug is well excreted by the kidneys and does not accumulate in cells.
Compound
The main active ingredients are meglumine sodium succinate, meglumine and succinic acid, the weight fraction of which per 100 ml of volume is 15, 8.7 and 5.2 milligrams. Potassium and magnesium chloride, sodium hydroxide, and water for injection help enhance the work of the active ingredients. To ensure that all substances retain their beneficial properties, the medication can only be stored in a dry place, protected from light. During long-term transportation, according to the instructions, freezing of the drug is allowed.
Release form
Reamberin is produced and supplied to pharmacies in several forms:
- One and a half percent solution for infusion in glass containers of 100-200 or 500 ml. Each bottle is tightly sealed with a rubber stopper, with a metal cap on top. Complete with the Reamberin solution, the pharmacist must provide instructions for use.
- Reamberin solution in a polymer container made of multilayer film. The product goes on sale in 250 or 500 ml containers. When purchasing in bulk, each package should contain 20-32 containers plus instructions for use for each batch.
Reamberin - what is it prescribed for?
The main purpose of Reamberin is to remove chemicals, toxins, free radicals and their derivatives from the body. In this case, the injection solution can be recommended for both children and adults. Reviews about the drug are mostly positive, so the product is actively used by doctors. You can outline a short list of why Reamberin is dripped:
- to eliminate the state of shock after receiving severe burns, with traumatic, infectious-toxic or hemorrhoidal syndrome;
- in case of poisoning of the body with toxic or medicinal drugs;
- to eliminate the icteric form of viral hepatitis in the chronic stage;
- after severe blood loss, artificial anesthesia;
- for patient recovery in the postoperative period;
- in case of acute respiratory or heart failure, circulatory disorders in internal organs of various origins;
- for complex therapy of psoriasis.
Contraindications
Reamberin intravenously should be used with caution during pregnancy, while breastfeeding and in patients who have an intensive development of an alkaline blood reaction. The following are indicated as categorical contraindications to refusal in the instructions for the Reamberin solution:
- severe pathology of the kidneys or liver;
- individual intolerance to the entire composition or its individual components;
- cerebral edema, traumatic brain injury.
Overdose
Reamberin, when prescribed dosages are exceeded, can lead to the development of arterial hypotension..
In this case, it is necessary to refuse further use of the solution and seek medical help to prescribe symptomatic therapy. When carrying out symptomatic treatment, the use of various drugs is indicated. Gastric lavage, diuresis and sorbing agents are not effective.
If necessary, hypertensive drugs, polyglucin or calcium chloride may be prescribed to eliminate signs of overdose.
Drug interactions
The drug can be prescribed together with antibiotics, glucose and water-soluble vitamin complexes. Such a combination is necessary in some cases.
When using other medications during the period of prescribing the solution, it is recommended to inform the treating specialist in advance. Such measures will help avoid possible drug interactions.
The combined use of the drug with calcium succinate should be avoided, since such interaction may result in the formation of a precipitate of the second drug.
special instructions
Due to the activation of aerobic processes in the body by the drug, a decrease in the concentration of glucose in the blood and the appearance of an alkaline reaction in urine are possible. In patients with diabetes mellitus and patients with reduced glucose tolerance, periodic monitoring of blood glucose concentrations is required. If the color of the solution changes or there is a precipitate, the use of the drug is unacceptable.
Effect on the ability to drive vehicles and machinery It is not recommended to drive vehicles or operate machinery during a course of treatment with REAMBERIN®.
