Which is better Sorbifer or Ferrum Lek: comparison and differences

A rapid increase in hemoglobin is only possible when using medications with iron. As with any pathology, the choice of medications should take into account the diagnosis, characteristics of the body and the prescribed medication. Most often, two drugs are used to eliminate iron deficiency: Sorbifer Durules or Ferrum Lek. What is the difference between them, and what are the advantages of each?

Comparison of the effectiveness of Ferrum Lek and Sorbifer durules

The effectiveness of Ferrum Lek is quite similar to Sorbifer Durules - this means that the ability of the medicinal substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Ferrum Lek is more pronounced, then using Sorbifer Durules, even in large doses, will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - Ferrum Lek and Sorbifer Durules are approximately the same. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

How to take Sorbifer Durules?

Iron deficiency anemia is a dangerous condition that is accompanied by a decrease in the concentration of hemoglobin in the blood, which affects all organs. To normalize the patient's condition, drugs containing iron are used, including Sorbifer Durules.

Release form and composition

Sorbifer Durules is an iron preparation that compensates for the lack of trace elements in the body and restores hemoglobin levels. It eliminates manifestations of anemia, including weakness, dizziness, psycho-emotional disorders, and asthenia. The main active ingredients of the product are ferrous sulfate and ascorbic acid, which improves the absorption of the microelement.

Anhydrous iron sulfate is considered one of the most bioavailable forms of the microelement, due to which it has high therapeutic activity.

The drug is available in the form of tablets made using special technology.

They contain 320 mg of ferrous sulfate and 60 mg of ascorbic acid; povidone, magnesium stearate, carbomer, macrogol, titanium dioxide, etc. are used as excipients. The tablets are packaged in bottles of 30 or 50 pieces, costing about 250 rubles.

Therapeutic effect

Sorbifer Durules tablets are manufactured using technology that ensures the gradual release of active ingredients over 6 hours. The drug shell disintegrates under the influence of intestinal peristalsis, the active substance is gradually released and absorbed in the duodenum and jejunum.

The binding to plasma proteins is about 90%.

Black feces when taking iron supplements are associated with the excretion of microelement residues, are considered a normal variant and do not require therapy.

Part of the altered microelement enters the bloodstream, the other remains in the epithelial layer of the intestine, after which it also enters the blood or exits with feces.

Iron is transported to organs in the form of transferrin, which binds to extracellular receptors and penetrates the cytoplasm. The mechanism of action of Sorbifer ensures rapid restoration of iron concentration in the body and reduces the likelihood of side effects.

Indications for therapy

The medicine is used to treat iron deficiency anemia during exacerbation or relapse. Can be used to prevent low iron levels and related complications in pregnant women, nursing mothers and blood donors.

Sorbifer Durules during pregnancy does not have a negative effect on the child's body, but requires careful use, preferably under strict medical supervision - an excess of iron in the blood can be more dangerous than its deficiency.

Mode of application

Sorbifer Durules tablets are intended for oral administration. They must be drunk whole 30 minutes before meals, without crushing or chewing, with a sufficient amount of liquid - at least 200 ml. The standard dosage for adults and children over 12 years of age is 1 tablet twice a day (morning and evening), but if necessary, the doctor can change the treatment regimen.

The drug is ineffective for other types of anemia, but can be used as a prophylactic agent, since one pathology is often accompanied by another.

For the treatment and prevention of anemia during the first 6 months, 1 tablet is prescribed daily.

In the third trimester and breastfeeding period, the drug should be taken in the amount of 1 tablet 2 times a day. The course of treatment is 3-6 months until the condition is completely normalized.

Side effects

Due to the slow release of the active component, Sorbifer Durules rarely causes side effects. In some cases, the following reactions are possible:

• digestive disorders - pain in the epigastric region, nausea, ulcerative lesions of the mucous membranes, diarrhea or constipation;
• allergies accompanied by itching, skin rash; if there is hypersensitivity, the patient may experience anaphylactic shock;
• headaches, insomnia or drowsiness, increased excitability;
• in rare cases, patients develop damage to the kidneys and pancreas, cardiovascular disorders, and changes in clinical blood test values.

Side effects after administration usually occur when using high doses of the drug and are associated with the content of ascorbic acid in the composition. To reduce the likelihood of adverse reactions, you can reduce the dosage by 50%. If your condition worsens seriously, you should stop taking the medication and consult a doctor.

Contraindications for use

Contraindications to the use of Sorbifer Durules include the following diseases and pathologies:

• individual intolerance to the components of the drug;
• gastrointestinal diseases associated with obstruction and ulcerative lesions;
• any disturbances in the metabolism, absorption or excretion of iron from the body;
• increased susceptibility to thrombosis;
• urolithiasis disease;
• diabetes;
• fructose intolerance;
• anemia not associated with iron deficiency;
• hemochromatosis (increased concentration of trace elements in the blood).

The drug is not prescribed to children under 12 years of age. To prevent complications, before therapy it is necessary to do a blood test to determine the concentration of iron in the blood. If the hemoglobin level increases, use is strictly prohibited.

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When taking Sorbifer Durules, it is important to follow the instructions for use. Excess iron in the blood is a dangerous condition that can lead to serious complications. If vomiting, diarrhea, drowsiness, convulsions and other alarming symptoms develop, you should immediately consult a doctor.

special instructions

Sorbifer Durules has low compatibility with most antibiotics, thyroid hormones, levodopa, methyl dopa and cloronate, as it reduces the absorption of the active substances of these drugs.

The interaction of the drug with antacid medications containing magnesium carbonate and aluminum hydroxide leads to a decrease in the absorption of iron.

The simultaneous use of several iron-containing drugs can lead to excessive accumulation of the trace element in the body and unpleasant consequences.

Analogues and substitutes of the drug

Analogues of the drug include iron-containing drugs - Maltofer, Tardiferon, Ferrum Lek, Totema, Fenyuls, etc. Some analogues of Sorbifer Durules are cheaper, but it is worth considering that the form of iron and the composition of auxiliary components may differ. Before replacing one product with another, you should consult a specialist.

Which is better Sorbifer or Maltofer?

Maltofer and Sorbifer are drugs that have a similar mechanism of action and are used to treat iron deficiency anemia and replenish the lack of trace elements in the blood.

They have a similar list of indications, but contain different forms of iron.

Maltofer contains a compound of a macromolecular type complex, the structure of which is as close as possible to the ferritin protein contained in the human body.

Sorbifer contains iron in a different form, but at the same time includes ascorbic acid, which improves the absorption of the active component.

It has a quick effect and is used when it is necessary to normalize the patient’s condition as soon as possible. Maltofer is absorbed gradually, and the therapeutic effect is noticeable only after several weeks of use.

It is actively used in pediatrics, but is prohibited for use in the first trimester of pregnancy.

Sorbifer or Ferrum Lek: which is better?

Ferrum Lek is another common analogue of Sorbifer, which contains ferric hydroxide and is available in several forms - chewable tablets, syrup, solution for intramuscular injection.

The drug is absorbed faster, so the therapeutic effect is noticeable within 15-30 minutes after administration, but Sorbifer’s accumulative capacity is higher, so it is enough to take it 1-2 times a day.

The duration of the course is approximately the same - approximately 3-5 months.

The difference in the cost of drugs depends on the release form of Ferrum Lek. Chewable tablets are cheaper than a package of Sorbifer; syrup and solution for infusion are usually more expensive. In addition, contraindications and side effects of drugs are slightly different, so before use you should study the instructions for use.

What is better Totem or Sorbifer?

The Totema preparation is based on several microelements - iron, copper and manganese. Iron is necessary for normal metabolic processes in the body, and copper and manganese contribute to its absorption.

Totema is considered a safer drug and can be used during pregnancy, breastfeeding and in infants over 3 months.

The drug also has fewer side effects than Sorbifer - these include allergic reactions and digestive disorders, and more serious disorders are observed in isolated cases.

If you believe the reviews of patients, Totema gives a slower and weaker effect than Sorbifer. The product is produced in the form of ampoules, which are dissolved in liquid and taken orally. A box of ampoules costs less than Sorbifer, but considering that the dosage is 2-4 pieces and the duration of administration is 3-5 months, the course of treatment can be much more expensive.

Fenyuls or Sorbifer: which is better?

Fenyuls is a complex preparation that includes ferrous sulfate, as well as vitamins B, C and PP. It is produced in the form of capsules with granules inside, due to which the process of breakdown and release of active components is slower.

If we compare Fenyuls with Sorbifer, the latter contains three times more iron, so it is prescribed for severe iron deficiency anemia.

In addition, it has virtually no negative effect on the gastric mucosa, as it is destroyed in the intestines.

The Sorbifer analog Fenyuls is used in cases where it is necessary to achieve a quick effect from taking it - only a month is needed to normalize the level of iron in the blood. At the same time, the drug has a short-term effect (the active substance practically does not accumulate in the body), so it is used for unmarked decreases in hemoglobin and satisfactory condition of patients.

When choosing iron-containing drugs, you need to pay attention not to the cost, but to the composition of the drug and instructions for use. Incorrect selection of medication can aggravate the patient's condition and cause serious complications. Before treatment, you should consult a specialist.

When is Sorbifer Durules used?

Sorbifer Durules is an effective iron-containing drug used to treat a decrease in hemoglobin in the blood and the development of iron deficiency anemia. This is a potent drug that has a number of contraindications and side effects that you should familiarize yourself with before use.

Do not forget that an excess of iron is no less dangerous to health than its deficiency, so the tablets must be taken correctly, without exceeding the dosage and duration of use. If you need to take analogues of the drug, you should consult your doctor, since all iron-containing products have a different composition of additional substances and features of use.

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Comparison of safety of Ferrum Lek and Sorbifer durules

The safety of a drug includes many factors.

At the same time, in Ferrum Lek it is quite similar to Sorbifer durules. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Ferrum Lek, as well as Sorbifer durules, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Ferrum Lek does not have any risks when used, just like Sorbifer Durules.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Ferrum Lek and Sorbifer Durules.

Comparison of addiction in Ferrum Lek and Sorbifer durules

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “syndrome o” in Ferrum Lek is quite similar to the similar values ​​in Sorbifer durules. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Ferrum Lek the meaning of the “syndrome” is quite small, however, the same as in Sorbifer durules.

Indications for use

A combined antianemic agent is often prescribed for iron deficiency of various etiologies. According to the instructions, “Sorbifer” will be effective in the following cases:

• prolonged bleeding (gastrointestinal, uterine);
• during periods of severe illness that cause microelement deficiency;
• during pregnancy and breastfeeding;
• during a period of intensive growth;
• with anemia caused precisely by a lack of iron;
• with malnutrition.

Comparison of side effects of Ferrum Lek and Sorbifer durules

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Ferrum Lek's side effects are almost the same as those of Sorbifer Durules. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Ferrum Lek is similar to Sorbifer Durules: how quickly the body recovers after taking it and whether it recovers at all.

Ferric iron preparations

Benefits of ferric iron supplements

• Low toxicity. They cannot be overdosed.
• Better tolerated.
• They can be taken before, during, and after meals, without fear of inflammation or ulceration of the gastrointestinal mucosa.
• Fewer drug interactions.
• Fewer food interactions.

Disadvantages of ferric iron preparations

They act more slowly, so the treatment time increases.

If you need to quickly increase your iron level (surgery is coming up, severe anemia, etc.), at the beginning of treatment the doctor will most likely prescribe a ferrous iron supplement. In the future, he can transfer the patient to a ferric iron preparation if he does not tolerate divalent iron.

Let's look at the features of some popular drugs in this group.

Comparison of ease of use of Ferrum Lek and Sorbifer durules

This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.

The ease of use of Ferrum Lek is approximately the same as that of Sorbifer Durules. However, they are not convenient enough to use.

The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.

Last update date: 2020-12-04 13:43:07