Vitamin B6. Benefits for the body, products, drugs in ampoules. Instructions for use, products containing, tablets, injections. Indications

Vitamin B6 is one of the B vitamins. It is one of the most essential substances for humans. Vitamin B6 is called pyridoxine. It supports the body's defenses and protects against viruses. This vitamin is highly soluble in water, and therefore does not remain in the human body for a long time and is excreted in urine. Therefore, it cannot accumulate in organs or tissues. Therefore, the need for it must be replenished daily with food. Pyridoxine is resistant to high temperatures, and therefore, after cooking, its concentration in products practically does not decrease. True, it quickly disintegrates when exposed to sunlight.

What is pyridoxine useful for?

This vitamin is simply indispensable for a strong immune system. It controls the formation of antibodies that protect the body from disease. If a person has a normal amount of pyridoxine in his blood, then his immunity is strong, the person rarely gets sick and feels good. This microelement also helps remove homocysteine ​​from the human body, an amino acid that contributes to the occurrence of stroke and heart attack. It is pyridoxine that can resolve cholesterol plaques, blood clots and makes the blood more fluid.

Vitamin B6 also performs the following functions:

• regulates the transport of sugars and minerals into the blood;
• stimulates brain function, improves mental performance;
• helps the adrenal glands and thyroid gland function normally;
• participates in the synthesis of enzymes and hormones;
• regulates the amount of fat in the body;
• regulates the amount of cholesterol and sex hormones in the blood;
• removes harmful substances from the body: toxins and decay products;
• for edema it has a diuretic effect;
• normalizes the degree of acidity in the stomach;
• helps to form red blood cells;
• normalizes the state of the nervous system;
• play a huge role in the formation of DNA, as they restore nucleic acids.

Pyridoxine (Vitamin B6) - what kind of vitamin is it?

Vitamin B6 is also called adermin or factor Y (old names that were used during the discovery and initial study of why the body needs it).
This is the general name for chemical compounds that exhibit pyridoxine activity: pyridoxal, pyridoxine and pyridoxamine. Otherwise they are called “B6 vitamers”, which are of great importance in proper human nutrition to ensure the normal functioning of many organs and systems.

Vitamin B6 - what is its role in the body, what it is responsible for and what foods it is found in.

The history of the discovery of the substance can be divided into 3 stages:

1. 1934 - discovery of a new substance during the study of yeast preparations;
2. 1938 - a substance was isolated from yeast and rice bran that helped cure symmetrical dermatitis. The new chemical compound was named adermin;
3. 1939 - the structure of the substance was determined, it was named pyridoxyl (pyridoxine).

Vitamin B6 test

Vitamin B6 is a coenzyme of amino acids and glycogen. It is involved in the production of adrenaline, norepinephrine, dopamine, and hemoglobin. In the body, the substance is found in the muscles. When testing in laboratories, vitamin B6 is detected in the blood. The main method for determining a molecule is chromatography . Sometimes a ferrichloride test for vitamin B6 is done.

Determination of vitamin B6 using chromatography

To determine the concentration of vitamin B6, a blood test requires compliance with a number of restrictions. 8-12 hours before the procedure they stop eating, but you can drink still water without additives. You should not smoke 30 minutes before blood collection. Fluid samples are taken from a vein for testing.

The analysis is prescribed if symptoms indicating a deficiency of vitamin B6 are recorded in adults and children. The indications will be:

• dermatitis;
• diarrhea;
• cheilitis;
• stomatitis;
• celiac disease;
• gastrointestinal diseases;
• alcoholism;
• malnutrition;
• intravenous nutrition.

Blood tests are indicated to determine the level of vitamin B6 in the blood in cases of alcohol intoxication, chronic infection, prolonged fever, hypothyroidism - such patients need more adermin.

Normal readings of vitamin B6 in the blood: 8.7-27.2 ng/ml.

Exceeding the upper threshold is observed with prolonged intake of additional volumes of Adermin. Low levels are not uncommon in intestinal, kidney diseases, or treatment with antibiotics.

Physiological role

Vitamin B6 and why the body needs it is the main question in scientific research. Once in the human body, as a result of multi-stage reactions, B6 vitamers are converted into pyridoxal phosphate, an integral part of many enzymes that catalyze the most important processes of assimilation and dissimilation.

They are as follows:

• hemoglobin synthesis;
• histamine;
• lipid and carbohydrate metabolism;
• stages of protein synthesis during which hereditary information from a gene is transformed into RNA or protein of the body.

With its participation, hormones and neurotransmitters are synthesized: adrenaline, norepinephrine, serotonin, dopamine, aminobutyric acid.

Physiological role:

• The properties of any organism are determined by the proteins from which it is built. The unit of structure of any protein is amino acids. Our body can create some on its own, while we get many from food. The most important property of amino acids is intertransformation. That is, if the body currently does not have enough for the synthesis of a certain amino acid, then it can be created from another that is available in excess. It is the process of mutual transfer of amino acids that triggers and regulates pyridoxine.
• This substance promotes better absorption of food chemical compounds by the villi of the small intestine and their transfer to cells and tissues.
• Ensuring the vital activity of body cells is carried out thanks to ATP. It is adenosine triphosphate that cells use as an energy depot. The ladder of reactions that results in the synthesis of ATP in mitochondria and plastids is called the Krebs cycle. The course of this multi-stage process, as a result of which ATP is synthesized from carbohydrates entering the body, occurs under the control of pyridoxine.
• The main property of nerve cells is the ability to excite. The excitability of the central nervous system requires the opposite effect - inhibition. Exaltation and convulsions are the result of excessive excitation and lack of inhibition in the central nervous system; it occurs when there is insufficient intake of pyridoxine in the body. Excitation is extinguished by the influence of neurotransmitters: serotonin, GABA (gamma-aminobutyric acid), which are products of decarboxylation reactions. This reaction takes place with the participation of pyridoxine. For the body, it is the coordinator of the normal functioning of the spinal cord and brain.
• Thanks to pyridoxine, the body synthesizes more siderophyllin protein, which transports iron from the intestines to the bone marrow. It is the hematopoietic organ. Iron is required to create hemoglobin, which is part of red blood cells. It provides transport of oxygen and carbon dioxide through the bloodstream.
• B6 increases the production of succinic acid and norepinephrine, which increase the metabolic rate: cells are renewed more energetically, rejuvenating organs.

Functions

Pyridoxine is a vitamin that is chemically active and is involved in many body processes. Its main actions include:

• Stimulation and acceleration of metabolic processes . The “lion’s” share of B6 is used to start and accelerate the metabolism of various types of substances - antibodies, enzymes, protective cells and mechanical components involved in the construction of skin, muscles and bone tissue. Scientists have also proven that pyridoxine improves the absorption of proteins from food and normalizes the processing of amino acids. For this reason, it is considered an important vitamin for bodybuilders and children, where weight gain and muscle growth are a common goal.
• Helps in the synthesis of neurotransmitters . Neurotransmitters are responsible for the functioning of the central nervous system (transmission of nerve impulses, organization of thought processes). In case of their deficiency, the risk of diseases and problems with the nervous system increases. Vitamin B6 normalizes the production of these vital elements. In addition, it is involved in a number of other processes that occur in the human central nervous system. It has been proven that regular intake of products with this vitamin guarantees improved memory, increased performance, improved coordination and concentration.
• Providing cells with glucose . Pyridoxine activates the body's production of elements that ensure rapid transport of glucose to cells. This means that energy levels depend on the sufficiency of B6 in the diet.
• Acceleration of hemoglobin production . The vitamin is responsible for the production of red cells in blood plasma. But here his participation is indirect. It acts as a catalyst (accelerator) for reactions with proteins and is involved in the production of hemoglobin.
• Normalization of amino acid metabolism . Considering why vitamin B6 is needed, it is worth noting its participation in the breakdown and production of a number of elements, including histamine, glutamine, prostaglandins and others. Each of them is important for the body.
• Helps in the breakdown of fatty acids (unsaturated). The mentioned process is doubly useful - the body is provided with an additional supply of energy due to the breakdown of fats, and the risks of accumulating excess weight are reduced.
• Support muscle fibers in tone . It has been proven that pyridoxine optimizes the delivery of glucose to cells, which activates metabolic processes. In addition, a sufficient level of B6 is a guarantee of heart health and stable functioning of internal organs.
• Normalization of lipid metabolism . It is known that pyridoxine is an element involved in optimizing cholesterol levels and maintaining blood vessels in proper condition. Thanks to this action, it is possible to avoid problems with the heart and blood vessels.
• Improving liver function . The effect of the element also has a positive effect on the functioning of the liver. A stable supply of vitamin guarantees tissue regeneration and disposal of harmful substances.

Physical and chemical properties

Pyridoxine and all its derivatives have a number of similar physical characteristics.

Chemical properties are determined by the presence of an aldehyde (or amine) and alcohol group in the substance:

• white crystals, odorless;
• soluble in alcohol-containing liquids;
• dissolves well in water;
• exhibits resistance to alkalis and acids;
• does not react with oxygen in the air;
• melting point - 160˚;
• sunlight and diffuse daylight have a destructive effect, so vitamin preparations should be stored in a dark place and dark glass;
• in acidic and alkaline solutions withstands heating up to 100-120˚C;
• during heat treatment during cooking, up to 40% of the vitamin is lost;
• quickly absorbed through the walls of the gastrointestinal tract;
• metabolization occurs in the liver;
• excreted from the body by the kidneys;

• enters cells in the form of phosphates;
• B6 vitamers are easily interconvertible;
• When interacting with acids, it forms salts.

Compatibility B1, B6 and B12

Three hydrophilic B vitamins - thiamine, pyridoxine and cyanocobalamine - are the most important coenzymes of nervous system enzymes.

Thiamine is responsible for the biosynthesis of the neurotransmitter acetylcholine. Cobalamin – for myelin synthesis. Pyridoxine – for the transmission of impulses between nerve cells and the production of inhibitory mediators.

Thanks to a similar mechanism of action, these substances can compete with each other, inhibiting and destroying each other.

Compatibility B6 and B1

Thiamine (vitamin B1) enhances or provokes a deficiency of riboflavin, pyridoxine, and niacin. B6 spends its activity on inhibiting thiamine. The administration of injectable drugs and the use of drugs purchased separately must be alternated .

Compatibility B6 and B12

Vitamin B6 is destroyed when interacting with B12 (cyanocobalamin). This is facilitated by cobalt ions included in B12. Therefore, their solutions cannot be mixed in the same syringe.

To replenish vitamin deficiency using injections, it is advisable to inject a course of first one drug, and then another.

Scientists have found that substances that interact poorly with each other are very effective in combination for treating severe diseases of the nervous system.

Experts solved the problem of incompatibility by adding a stabilizer, potassium hexacyanoferrate, to the drug that combines B1, B6 and B12.

The stabilizer prevents the breakdown of vitamins and negative interactions with each other. Medicines produced according to this principle:

• Milgamma;
• Combilipen;
• Neurovitan;
• Neurorubin;
• Cardonate;
• Neurobion.

They are available in tablets and ampoules.

Why does the body need pyridoxine?

Vitamin B6 and why the body needs it have been studied for a relatively short time. But now medical statistics say that more than a hundred diseases and disorders begin with pyridoxine deficiency. And every sixth person on the planet experiences this deficiency. It is impossible to list all the problems that arise with hypovitaminosis B6.

In the human body, the course of the most important processes and the prevention of serious diseases are associated with it:

• synthesis of transaminase in the liver for complete protein metabolism;
• lipid metabolism, which is very important for preventing obesity and maintaining the structure of cell membranes;
• carbohydrate metabolism, which helps regulate blood sugar levels;
• beneficial effect on the organ of vision;
• prevention of blood clots;
• optimization of blood pressure;
• the diuretic effect helps remove excess fluid from the body, relieving swelling on the face and limbs;
• reducing the risk of cancer;
• with its participation, neurotransmitters and joy hormones are produced, which has a positive effect on the central nervous system and vital functions in general;
• the possibility of stone formation in the gall bladder and renal pelvis is reduced;
• prevention of damage to the cardiovascular system: ischemia, atherosclerosis, heart attack;
• maintaining and increasing immunity;
• high-quality absorption of magnesium and cobalt in vitamin B12 by tissues, as well as the synthesis of hydrochloric acid.

Separately, it should be noted the importance of pyridoxine for the female body. This vitamin maintains the balance of sex hormones, reducing the risk of tumors. It must be taken by women using hormonal contraceptives, as they significantly reduce the level of the vitamin in the blood.

During pregnancy and before menstruation, when estrogen levels rise, it is also necessary to replenish pyridoxine. Of course, the beauty of hair and skin plays an important role for women, the healthy appearance of which directly depends on a sufficient supply of vitamin B6.

Why does the body need it?

Pyridoxine is activated by the liver. Through a complex mechanism, it is converted into coenzymes necessary for:

• Formation of porphyrins necessary for the production of heme, a component of hemoglobin;
• Formation of niacin from tryptophan;
• Metabolism of vital amino acids;
• Formation of energy reserve – participation in glycogen metabolism;
• Synthesis of DNA precursors - purine nucleotides, thymidylate;
• Catabolism of thyroid enzymes;
• Lipid synthesis;
• Release of substances responsible for the transmission of impulses between neurons of the nervous system;
• Production of a mediator of inhibition of the central nervous system, by splitting carbon dioxide from glutamic acid.

Why does the human body need vitamin B6?

Vitamin B6 for a bodybuilder

Vitamin B6 and why the bodybuilder’s body needs it is no secret: the athlete’s primary task is the formation of muscle mass. Muscle tissue is built from protein. Since pyridoxine regulates the processes of protein synthesis, this particular vitamin must be consumed when doing bodybuilding.

Training requires a lot of effort, so enzymes and hormones that are formed in the body with the participation of vitamin B6 increase the body's endurance and stimulate metabolic processes.

Eggs and their derivatives

Eggs are good for maintaining strength and health. Despite the presence of cholesterol, they also contain lecithin, which prevents an increase in the level of bad cholesterol. Eggs are one of the foods that contain it, our vitamin B6.

The largest amount of pyridoxine is found in the yolk. But it can only serve as an additional source - it is impossible to consume 434 grams of eggs per day.

Pyridoxine in cosmetology

Pyridoxine is an essential B vitamin that supports the health of the skin and its derivatives: hair and nails. To achieve a lasting effect, the external use of vitamin preparations is combined with the consumption of vitamin-rich foods.

With a lack of pyridoxine in the body, the following occurs:

• the appearance of dandruff;
• itching, skin irritation;
• brittleness and dryness of hair;
• increased hair loss;
• slow growth of nails and hair;
• “jams” in the corners of the lips;
• conjunctivitis;
• breaking nails;

• acne;
• excessively dry scalp and entire body.

If such symptoms appear, you should think about replenishing the lack of vitamin in the body.

In cosmetology, various masks are used for the skin and its derivatives with the addition of the drug pyridoxine and its analogues. Competent and regular use of vitamin B6 helps tidy up the scalp and face, the quality of hair and nails, normalize weight and correct the figure.

For example:

• by strengthening the roots, hair loss is significantly reduced;
• nails become shiny and brittleness decreases;
• greasiness disappears, skin fat metabolism is normalized;
• the hair does not become dirty, becomes elastic, and shine appears;
• hair and nails grow much faster;

  
  Vitamin B6 has a positive effect on the health of hair and nails.

• inflammation on the skin affected by acne is relieved, the skin heals quickly;
• antioxidant properties maintain healthy skin and slow down the aging process;
• Due to the stimulation of metabolic processes and proper nutrition by pyridoxine, it becomes possible to reduce and stabilize weight.

In the late 1970s, American nutritionists developed a “miracle” diet that captured the minds of those suffering from excess weight. The main secret of the magic diet was a much larger amount of vitamin B6 than the usual daily intake. Together with apple cider vinegar, flaxseed and soybean oil, it gave a remarkable effect of burning excess fat tissue.

Vitamin for beauty

1. Benefits for the face

It is used in ampoules to treat an impressive list of pathologies in the epidermis. Even if the situations are serious, the remedy will help resolve the problem. Pyridoxine is a powerful antioxidant, therefore it will prevent rapid skin aging. All kinds of face masks are prepared with it.

• Moisturizing and nourishing mask. You need to grind half a banana, pour the mixture with a tablespoon of sour cream and 1 ampoule of pyridoxine. Leave the mixture on your face for a third of an hour, then wash it off. The procedure can be repeated once every three to four days.
• Anti-acne mask. 1 tbsp. spoon of honey and 1 tbsp. A spoonful of kefir is filled with 1 ampoule of vitamin. You can supplement the mask with 1 teaspoon of lemon juice. Before application, the skin must be cleansed and steamed. You can keep it for a third of an hour, repeat every three to four days.
• Mask with vitamin B 6 and B Take ½ ampoule of each product, 1 tbsp. a spoonful of kefir and 1 teaspoon of lemon juice. The mask has a tonic and rejuvenating effect. Can be applied for no more than a quarter of an hour once a week.

It is worth remembering that the substance can cause allergies. Therefore, before use, it is better to protect yourself and do a sensitivity test to the element (apply a few drops of the drug to sensitive and delicate skin and see the reaction).

Masks with B vitamins, when used regularly, can make the face and body look younger and restore the skin. Pyridoxine nourishes the skin, moisturizes it, protects, restores and helps protect against the negative effects of the environment: cold, heat, sun, wind.

Vitamin B6 toxicity and contraindications

Pyridoxine and its analogues are not toxic substances. Even long-term use of the vitamin as a therapeutic agent did not cause a negative reaction from the body. Research has been conducted on various methods of introducing high concentrations of pyridoxine into the body of animals and humans for a long time. In some cases, allergic reactions may occur .

People with stomach diseases (gastritis, ulcers) and other parts of the gastrointestinal tract should be careful when taking pyridoxine, since pyridoxine increases the percentage of acidity. The use of the vitamin is contraindicated in cases of severe liver damage and coronary artery disease.

Milk and dairy products

Milk and its derivatives are also products containing vitamin B6. It contains proteins, calcium, and trace elements. It is recommended for use by nutritionists to support immunity and regulate intestinal function. Where it is, vitamin B6, can be seen in the table.

Analysis shows that the highest concentration of pyridoxine is found in cheeses. To meet the daily requirement, 476 grams are required.

Daily vitamin requirements for different groups of people

Fish and seafood

Fish and seafood are a source of many vitamins and nutrients. Including a resource containing vitamin B6.

Atlantic salmon, also called salmon, is richest in pyridoxine. To meet the daily requirement, 250 products per day are enough.

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Vitamin B6 absorption and methods of preservation

The vitamin, like all water-soluble compounds, is well absorbed by the body, freely penetrating through cell membranes.

The easiest way to replenish the vitamin is to eat foods rich in this substance. Unfortunately, various methods of preparation (heat treatment, preservation) have a destructive effect on chemical compounds, and a significant amount of the vitamin is lost.

Preservation “eats” up to 50-70% of pyridoxine, freezing takes away about 40% from products, and exposure to temperature destroys vitamin B6 by 80-90%.

Therefore, it is healthier to eat more raw vegetables and fruits, add bran and cereal sprouts to your diet, eat nuts, and use yeast when baking. The thermal effect can be “softened” by steaming (instead of frying) or by wrapping the baked product in foil.

Release forms

Chemical analogues of the vitamin were obtained synthetically:

• Pyridoxal phosphate - available in film-coated tablets of 0.01 and 0.02 g;
• Pyridoxine hydrochloride – tablets of 0.002, 0.005, 0.01 g, ampoules of 1 ml of 1% and 5% solution.

Pyridoxine hydrochloride passes through cell membranes more easily than pyridoxal phosphate and quickly enters the brain from the blood. But if the patient has liver pathology, a lack of zinc, magnesium, pyridoxal phosphate is preferable.

Is it possible to drink vitamin B6 from ampoules?

You can often hear suggestions in fashionable women's magazines to drink Adermin directly from ampoules. Some advise drinking without even diluting with water. The meaning of these recommendations is unclear.

The composition of the ampoule substance is designed for absorption of the vitamin through the blood. This ensures its rapid entry into the body, especially in case of intestinal poisoning, toxicosis in women, accompanied by vomiting and diarrhea.

Pyridoxine is prescribed in ampoules to patients with ulcerative lesions of the digestive system to prevent its contact with acidic gastric juice.

By drinking the concentrate from the ampoule, a person can cause a burn to the mucous membranes and stomach and a violent allergic reaction. And an unprotected substance, having passed through the digestive tract, will lose its activity

How to take the pills

Tablets, especially those protected by a shell (capsule), are designed to pass through the hostile environment of the digestive tract, without loss of beneficial properties.

They should be taken between meals or with food. It is better to divide the daily dose into equal parts.

A large dose of pyridoxine should be taken in the morning by people suffering from sleep disorders. When taking pyridoxine, you need to remember its compatibility with other vitamins and macroelements.

Table 5. Pyridoxine interactions

Reference! Activated carbon interferes with the absorption of vitamins.

Vitamin B6 deficiency in the body

Vitamin B6 and why the body needs it is described above.

Therefore, it is obvious that a lack of pyridoxine has consequences that are more serious than an overdose:

• depression, depression;
• manifestation of dermatitis;
• hypertension;
• anemia;
• general lethargy, weakness;
• insomnia;

• stones and sand in the kidneys;
• increased level of aggression;
• strong excitability of the nervous system;
• psychoses;
• suppression of heart activity;
• negative impact on the condition of blood vessels and blood clotting indicators;
• exacerbation of old diseases.

Pyridoxine deficiency in children manifests itself in the form of general weakness, muscle pain and spasms, numbness of the limbs, and in girls – premenstrual syndrome.

Why is deficiency dangerous?

Vitamin B6 deficiency develops due to metabolic disorders and poor diet. The first manifestations of deficiency:

• Deterioration in the appearance of the skin - cheilosis, seborrhea or dermatitis appears. The most susceptible areas are the areas around the nose and eyes.
• The deficiency is manifested by an itchy scalp and an increase in dandruff.
• Cracks in the corners of the mouth, jams.
• Stomatitis and so on.

If you ignore the first problems, then the deficiency leads to more serious consequences:

• Conjunctivitis and vision problems. The main reason is disruption of the normal functioning of the central nervous system.
• Problems with the nervous system - the appearance of irritability, deterioration in performance, a feeling of constant anxiety and loss of sleep.
• Malfunctions in the gastrointestinal tract. The main signs are vomiting, loss of appetite, nausea and others. Such symptoms appear in 90% of cases during pregnancy.
• Deterioration of brain function. It has already been noted that a lack of vitamin leads to a decrease in mental endurance and decreased mental flexibility.
• Malfunctions of the circulatory system, which is caused by low levels of plasma enzyme production. The problem makes itself felt by pressure surges, the appearance of anemia, vascular disease, and so on.
• Decreased immunity and excessive pain. The main reason is a decrease in the production of T-lymphocytes. The danger is that the symptom in question appears late, when the mild stages of deficiency are a thing of the past.
• Joint damage, arthritis. In this case, arthritis develops with a regular lack of the element (within 2-3 years).

Excess pyridoxine and overdose symptoms

Acceptable daily intake of vitamin B6 is 50-100 mg. With prolonged overdose (increasing the dose by 50-100 times), after a few years a state of hypervitaminosis develops, which can have unpleasant consequences.

They are as follows:

• convulsions;
• dizziness;
• nausea;
• skin rash;
• numbness of lips, arms and legs;
• anemia;
• fainting;
• lack of coordination;
• inhibition of the lactation process;
• accurate and detailed memory of dreams.

Such phenomena are extremely rare, since vitamin B6 does not tend to accumulate, and its excess is quickly removed from the body in the urine.

Symptoms of overdose disappear soon, for which you need to stop taking pyridoxine medications.

Natural replenishment

B6 is necessary for many biochemical processes. It takes part in the production of hormones, including sex hormones and serotonin, which is responsible for a good mood. Metabolism, proper absorption of protein compounds, and the formation of red blood cells are also under the patronage of pyridoxine. Thanks to B6, we receive protection from sudden surges in glucose levels. The average daily intake is 2 mg. The need varies depending on age and health status. More pyridoxine is required for the following conditions:

• pregnancy, breastfeeding;
• stress, increased physical and mental stress;
• diseases of the heart and blood vessels;
• living in low temperature conditions;
• high protein diet;
• work in chemical production.

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In such conditions, the need increases to 5 mg. Long-term lack of the required amount of B6 leads to hypovitaminosis, which manifests itself as symptoms:

• inhibition of nervous system functions - lethargy, apathy, irritability, depression;
• skin diseases - dermatitis, psoriasis, herpes;
• inhibition of intellectual processes;
• convulsive syndrome of the upper and lower extremities.

To avoid deficiency, you need to know which foods contain vitamin B6.

If you look at the chemical composition of any food source, it is easy to find one that contains vitamin B6. The list is long. It includes fruits and vegetables, meat and milk, eggs, seafood, plants, nuts and mushrooms. Sources containing vitamin B6 are not equal. Some contain large amounts of pyridoxine, while others have minimal presence. In order to correctly compose your diet, you first need to obtain information about which foods contain the most vitamin B6.

Indications for use

List of indications:

• acne in teenagers and young adults;
• people taking steroids;
• unsuccessful attempts to lose weight;
• women with increased estrogen levels (pregnancy, premenstrual period, use of oral contraceptives);
• diabetes;
• toxicosis (complex therapy);
• atherosclerosis;

• cardiovascular problems (risk of heart attack);
• dermatoses: psoriasis, acne, iridescent lichen, diathesis;
• nocturnal urinary incontinence;
• toxicosis;
• childhood autism;
• chronic alcoholism;
• hangover syndrome, withdrawal from binge drinking;
• radiculitis and other spinal disorders;
• fears and manias;
• Little's disease, Meniere's disease, epilepsy.

Vitamin B6 for alcohol intoxication: methods of application

It would seem, what do alcohol and vitamins have in common? In fact, our body really needs vitamins during alcohol intoxication; in fact, they act as the main assistants in eliminating poisoning.

• When drinking alcohol, our body becomes significantly weaker; it loses reserves of vitamins and microelements, since they are quickly eliminated during urination.
• Pyridoxine has a positive effect on liver function and also has a detoxifying effect.
• Popular experts say that vitamin B6, which is available in ampoules, can be taken orally. This should be done as follows: dissolve the contents of 1 ampoule in 100 ml of water, mix and drink. Thus, the alcohol in the body will be processed much faster, and the symptoms of the “illness” will be less noticeable.
• There is also an opinion that pyridoxine should be taken in advance, immediately before the upcoming event. The first dose of the drug should be taken 10 hours before, and the second - 4 hours before. before drinking alcohol. In total, you can take up to 150 ml of the substance, however, you need to understand that such doses are not considered daily, but “medicinal”. You can take the drug in any form, however, it will be much more convenient to do this by taking the vitamin in tablet form.

B6 and alcohol

• In case of severe alcohol intoxication, it is necessary to resort to the help of droppers. As a rule, glucose-saline solutions and vitamins are used for IVs. The advantage of droppers is that the substance that is injected into the body in this way goes directly into the blood, which means it acts quickly and effectively.
• It is important to note the fact that such vitamin B6 therapy is not the first medical aid for alcohol intoxication. If a person has severe alcohol poisoning, he must be urgently taken to the hospital, and before that he must be provided with complete rest and plenty of fluids. It is strictly prohibited to insert IVs yourself or for a patient without the appropriate skills. Firstly, you can harm a person by placing an IV incorrectly, and secondly, you can harm a person by administering the wrong drugs to him.

Sources of vitamin B6

Adermin (vitamin B6) is one of those synthesized by bacterial microflora in the human large intestine.

The content of different forms of the vitamin in plants and animal tissues can vary significantly:

• Pyridoxine is absent in plant organs or contained in minimal quantities. Pitaya, the edible fruit of cacti, is rich in this form of adermina. It is found in dairy products and meat. It is quickly destroyed during heat treatment, so almost no of it remains in cooked meat. Vegetarians should eat vegetables whose skins have been in contact with the ground (carrots, beets, potatoes, turnips).
• Sources of pyridoxal include cabbage of any variety, meat and green parts of some edible plants.
• Pyridoxamine can be obtained from animal and poultry muscle fibers.

Rice, millet or buckwheat porridge for breakfast satisfies a person’s daily need for pyridoxine. It is better if porridges and salads are seasoned with vegetable oil, which is rich in vitamin B6. It is recommended to include fresh fruits and vegetables (lemon, strawberries, cherries, bananas, tomatoes, cabbage) and freshly prepared juices in your diet every day.

Content in food

Table 1. Highest content of the substance in food sources

What foods contain vitamin B6?

Vitamin B6 in ampoules

Pyridoxine in ampoules is sold in pharmacies under different names.

The drugs have identical composition and differ only in the name of the manufacturer:

• Pyridoxine-Vial.

• Pyridoxine-Bufus.
• Pyridoxine hydrochloride.
• Pyridoxine.
• Vitamin B6.

In addition to being used for injections, vitamins in ampoules are used in cosmetology. Liquid pyridoxine is much more convenient to add to shampoos and creams than to crush tablets or dissolve powders. Taking this form of the vitamin orally does not bring the desired effect.

Mushrooms

Mushrooms have high nutritional value. Contains a large amount of vegetable protein, vitamins and minerals. The calorie content of mushrooms is low, which is useful for diets. The composition and amount of carbohydrates are close to those of plants; mushrooms themselves are classified as a separate kingdom because they do not contain chlorophyll. If you look at what other foods contain pyridoxine, mushrooms will take their rightful place in the list of sources.

When preparing for the winter, it is most useful to dry porcini mushrooms to preserve nutrients. 487 grams of mushrooms per day will maintain the required level of pyridoxine.

Vitamin B6 tablets

Most often, pyridoxine is prescribed in the form of tablets (capsules, dragees), which are convenient to take. They are quickly and easily absorbed by the body. Monovitamins are drugs that contain pure pyridoxine and are used to treat acute vitamin deficiency.

The following are on sale:

• Piridobene.
• Pyridoxine hydrochloride.
• Bartel Drugs Vitamin B6.
• Vitamin B6.
• Pyridoxine-N.S.

In addition, vitamin B6 is included in multivitamin complexes prescribed for prevention in the autumn-winter period, with reduced immunity.

They are:

• Milgamma.

• Angiovitis.
• Magne B6.
• Biotredin.
• Pentovit.
• Polyneurin.

All drugs are interchangeable; they are taken after meals in a dose determined by the doctor or indicated in the instructions.

Therapeutic and preventive prescriptions differ significantly in the number and timing of administration. You can only follow the instructions when using it for preventive purposes. In other cases, the course of treatment is determined by the doctor.

There are numerous mineral and vitamin preparations on sale, such as Complivit, Alphabet, Multi-Tabs, Centrum, Vitrum, which can be used independently to maintain immunity at different periods of life.

What vitamins contain B6?

Adermin is included in many combination complexes. There are many names of preparations with vitamin B6: Magne B6, Magnelis, Ginko biloba and others. There are two forms of release: tablets, injection solutions. Adermin is prescribed for:

• activation of tissue regeneration;
• improving the condition of the central nervous system;
• prevention of heart and vascular diseases;
• treatment of dermatitis;
• metabolism stabilization;
• stimulation of hematopoietic function.

The instructions for using vitamin B6 in ampoules recommend resorting to the remedy in case of poisoning - pyridoxine is considered an effective antidote.

Panangin plus vitamin B6 is popular . It is taken twice daily, 2 tablets with meals for a month. The drug reduces anxiety, improves the functioning of the central nervous system, and increases the ability to resist stress. Taking the supplement reduces the risk of atherosclerosis.

Panangin Plus Vitamin B6. Photo: natulife.ru

Motherwort with vitamin B6 is useful . This dietary supplement is recommended for menopause, against the background of aggressive, anxious behavior. It helps with diseases of the heart, blood vessels, and nervous system. The combined product is useful during periods of increased stress and fatigue.

Magne B6 vitamins are perhaps the most famous pharmacy product with adermin. The inclusion of pyridoxine increases the absorption of magnesium. The drug is useful for poor sleep, spasms, anxiety attacks and increased stress. It is prescribed as an element of complex treatment of nervous disorders. Magne B6 relieves the condition if palpitations are felt. The drug is approved from 6 years of age. It is recommended to take up to 3 ampoules (or 6 tablets) per day.

Magne B6 60 tablets. Photo: vseapteki.ru

Magne B6 has an analogue - vitamin Magnelis B6 . This complex is indicated for adults daily in the amount of 6-8 tablets. It is prescribed to children if the patient’s weight is more than 20 kg. The daily norm is 4-6 tablets. Magnelis B6 is recommended to be taken when there is a reduced concentration of magnesium in the circulatory system. As soon as the indicators are equalized, the course is completed.

Magnelis B6 line. Photo: vklimakse.ru

This is interesting! Pyridoxine enhances the effect of diuretics, cardiac glycosides, glutamic acid.

Vitamin B6 in ampoules

The pyridoxine solution is packaged in 1 ml ampoules. The concentration of the drug is 50-100 mg per 1 ml. The optimal option is chosen based on the needs of the body, age and diagnosis of the patient. Liquid vitamin B6 is used less often than tablets. It is prescribed if the patient is fainting, comatose, or suffering from severe vomiting. Adermin is administered by injection for mental disorders, during the recovery period after resection of the gastrointestinal tract. In the hospital, the drug is administered by injection if the patient needs a very high dosage. This is usually a one-time event.

Pyridoxine injections are indicated for manifestations of vitamin deficiency, hypovitaminosis:

• dermatitis;
• seborrhea;
• stomatitis;
• cracks on the lips;
• sleep disorders;
• conjunctivitis;
• nausea;
• loss of appetite.

Indications for prescribing a course of injections are:

• leukopenia;
• anemia;
• hepatitis;
• radiculitis;
• neuralgia;
• neuritis;
• hypertension;
• diabetes;
• depression;
• autism;
• dermatitis.

Pyridoxine is indicated in the treatment of epilepsy. It relieves severe symptoms of withdrawal from binge drinking. Adermin is an antidote for isoniazid and hydrazine. Injections are recommended if more than an hour has passed since taking a dangerous compound.

Prescription standards for:

• parkinsonism – 0.1 g daily; 20-25 injections per course;
• convulsive syndrome – 30-600 mg daily;
• depression – 0.2 g daily.

The drug is injected under the skin, into a muscle, or into a vein.

Pyridoxine hydrochloride 50 mg/ml. Photo: borimed.com

Vitamin B6 tablets

In cosmetology, vitamin B6 is valued for its ability to improve skin health and slow down aging. More often they use tablets or ointments with adermin. The following formulations are sold in pharmacies:

• monovitamins;
• multivitamin.

A specialist will help you choose the best option. For the beauty of skin, nails, and hair, vitamin B6 is usually obtained with a combined tablet product. Such drugs have a complex effect on the human body; components reinforce each other. Many complex formulations with pyridoxine have been developed. For example, there are special products aimed at rejuvenating facial skin: vitamin B6 is suitable for this due to its ability to slow down the aging process. If you choose drugs to treat a specific disease, you often resort to a monovitamin product.

Pure B6 is available under the names:

• Pyridoxine hydrochloride;
• Vitamin B6;
• Bartel Drugs Vitamin B6.

Capsule, tablet contains 10-100 mg of substance.

Vitamin B6 100 mg. Photo: shop.usa-4u.eu

The drug is indicated for cheilosis, seborrhea, glossitis. He is written out against the background:

• polyneuritis;
• vomiting;
• nausea;
• conjunctivitis;
• pathologies of the central nervous system.

Due to the minimal set of contraindications, vitamin B6 (prohibited only in cases of intolerance, ischemia and ulcers) is often used as an element of complex treatment:

• tuberculosis;
• hepatitis A;
• anemia;
• psoriasis;
• diathesis;
• enuresis;
• leukopenia.

Average prophylactic daily dose:

• adults – up to 4 mg;
• children – up to 2 mg.

For trigeminal neuralgia, 0.3-0.4 g of adermin is prescribed. Against the background of heart failure, it is recommended to take 0.1 g of the drug daily.

Vitamin B6 injections

Intramuscular or intravenous use of drugs containing pyridoxine is prescribed in cases where, for some reason, taking tablets is impossible or ineffective.

The cases are as follows:

1. Therapy requires a significant dose of the vitamin, which cannot be absorbed through the gastrointestinal tract when taking tablets and must enter the bloodstream. For example, for diabetes, some poisonings, disorders of hematopoietic function, diseases of the musculoskeletal system.
2. The person is unable to take pills. The reason for this may be mental disorders, fainting, vomiting, or connection to an artificial respiration apparatus.
3. Disorders of the gastrointestinal tract, in which normal absorption of the drug does not occur. Such phenomena may be a consequence of operations, peptic ulcers, or defects in the epithelium of the small intestine.

You can note the pain of injections with pyridoxine. To reduce pain, injection medications include lidocaine.

Daily requirement

When planning your diet, you should consider the following pyridoxine rate:

• An adult in good health needs 2-2.5 mg of B6 per day . On average, this is equivalent to eating 0.6 kg of bananas or 0.3 kg of fish.
• Children immediately after birth and up to six months need 0.2-0.3 mg .
• With age, the need for the element increases. So, from the age of six months the body needs 0.5 mg , and by 8-10 years already 1.5 mg per day .
• The body of women during lactation and pregnancy requires 2.5-3.0 mg of vitamin per day.

The need for pyridoxine increases in the following cases:

• While taking birth control pills or medications containing estrogen.
• During pregnancy, when the body synthesizes increased amounts of estrogen.
• While on a diet. Often the inability to lose weight is caused by a deficiency of this useful element.
• During the period of taking steroids (including cortisone).
• 14 days before the start of the menstrual cycle.
• In adolescence, when the fat glands are in the active stage of work.
• When playing sports or heavy physical labor, and so on.

Interaction with other substances

It is necessary to achieve better absorption of pyridoxine (vitamin B6) by the body in order to achieve the maximum therapeutic effect, for which you need to remember the interaction of drugs and their mutual influence on each other.

For example:

1. Vitamin B6 is better absorbed together with vitamins B2 and B5.
2. B1 and B12 neutralize the effects of B6.
3. Medicines against Parkinson's disease are antagonists to pyridoxine.
4. Penicillamine and cycloserine reduce its effectiveness.
5. Pyridoxine increases the effectiveness of diuretics.
6. In combination with magnesium, it provides maintenance therapy for diabetes.
7. Taking before drinking alcohol reduces the degree of intoxication.

Article design: Oleg Lozinsky

How to give injections correctly?

After visiting a doctor and making a diagnosis, injections of vitamins B1, B6, B12 are often prescribed. And here it is worth making a decision - to do the injections yourself or to involve the help of medical professionals.

B6 and B12 injections are usually given intramuscularly. There are two options:

• stab in the thigh;
• inject into the buttock.

The first option is good because you can easily do the work yourself.

The algorithm of actions is simple:

1. Use a cotton swab with alcohol to treat the injection site (hands must be clean, they can also be treated).
2. The ampoule with the substance is opened.
3. A needle is placed on the syringe.
4. Air is released and the drug is drawn in.
5. This is followed by pressing the piston until the liquid appears from the edge of the needle (the air should come out of the syringe completely).
6. With a sharp movement, the needle is driven into the desired place, and the drug is slowly injected.
7. The injection site is treated with alcohol.

It is worth considering that B6 and B12 injections are quite painful, so it is recommended to do them with strict adherence to the given technique.

Vitamin B6 for poisoning of animals, dogs: dosage

Pyridoxine can rightfully be considered a universal drug, since it is used for both people and animals. Dogs very often pick up various crumbs and leftover food while walking along the street. Often it is on the street that animals can find “gifts” in the form of various poisons. One type of antidote is vitamin B6.

This remedy is effective in case of animal poisoning with isoniazid. The latter is a medicine that is used to treat a disease such as tuberculosis.

• If after a walk you see that the animal has lost activity, has become drowsy, is salivating too much, or has convulsions, act immediately
• For an animal weighing about 20 kg you will need approximately 5 ml of the substance
• If the animal is larger, you will need about 7 ml of the substance
• Administer intramuscularly
• It is important to understand that it is very difficult to overdose on pyridoxine, so do not inject doses less than those indicated above. Otherwise, the vitamin may not be enough and it will not have the desired effect.
• After administering the drug, the animal must be taken to a veterinary clinic. If your dog is not having seizures, you can also give him 20 ml of activated charcoal dissolved in water. To do this, pour the mixture into a syringe and inject it into the mouth (without a needle)