Zorex - description of the drug, instructions for use, reviews

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Manufacturers: Valenta Pharmaceuticals

Active ingredients

• Sodium dimercaptopropanesulfonate
• Calcium pantothenate

Disease class

• Mental and behavioral disorders caused by alcohol use - harmful use
• Mental and behavioral disorders caused by alcohol consumption - dependence syndrome
• Mental and behavioral disorders caused by alcohol consumption - withdrawal state
• Toxic effect of metals
• Arsenic and its compounds
• Cardiac glycosides and drugs with similar effects

Clinical and pharmacological group

• Not indicated. See instructions

Pharmacological action

• Detoxification
• Hepatoprotective
• Antioxidant

Pharmacological group

• Detoxifying agents, including antidotes, in combinations

Pharmacological action of Zorex

Unithiol (sodium dimercaptopropanesulfonate) is the active ingredient of the drug Zorex, has a detoxification, hepatoprotective and antioxidant effect. When interacting with ethanol half-life products and thiol poisons, the sulfhydryl active groups of unithiol form non-toxic complexes, which are excreted in the urine over time.

Calcium pantothenate, which is part of Zorex, enhances the detoxification effect of sodium dimercaptopropanesulfonate.

Once in the body, unithiol penetrates along with the portal bloodstream into the liver, where it quickly binds to acetaldehyde, thereby ensuring the removal of ethyl from other tissues and organs. Also, when studying the effect of the drug on the body, it was confirmed that Zorex activates alcohol dehydrogenase.

Zorex Morning tablets contain acetylsalicylic acid, which inhibits platelet aggregation, has antipyretic, anti-inflammatory and analgesic effects, inhibiting the enzymes COX-1 and COX-2, and disrupts the synthesis of prostaglandins.

Release form

According to the instructions, Zorex is produced in the form of gelatin hard capsules of sizes No. 0 and No. 00, with a pink cap and a white body, inside which contains white powder and granules with a creamy tint; the manufacturer allows the presence of a slight specific odor. Capsules are produced in blister packs of 10 pcs. (No. 0) and 2 or 5 pcs. (No. 00). One capsule of Zorex size No. 0 and No. 00 respectively contains:

• 150 or 250 mg unithiol (sodium dimercaptopropanesulfonate);
• 7 or 10 mg calcium pantothenate;
• 113.5 or 120.2 mg microcrystalline cellulose;
• 9.1 or 12.2 mg citric acid;
• 29.3 or 40.2 g of pregelatinized starch;
• 30 or 50 mg magnesium hydrogen phosphate trihydrate;
• 6.1 or 9.4 mg povidone;
• 5 or 8 mg of aerosil (colloidal silicon dioxide).

The gelatin shell of the capsules contains azorubine, gelatin and titanium dioxide.

Zorex Morning is produced in the form of white or creamy-white effervescent flat-cylindrical rough tablets, with a characteristic odor and chamfer in strips of 2 pieces; the manufacturer allows light marbling. One Zorex tablet contains:

• 324 mg acetylsalicylic acid;
• 0.08 g of succinic acid;
• 1.474 g citric acid;
• 2.013 g sodium bicarbonate;
• 0.048 g sodium benzoate;
• 0.001 g povidone;
• 0.04 g lemon flavor;
• 0.02 g lime flavor.

How to treat an allergic reaction

Our readers who suffered from an allergy to Zorex share their experiences and tell us how they were treated for this allergy. In case of allergies, be sure to contact an allergist so that he can select individual treatment for you. Below we describe what is usually prescribed to victims of Zorex:

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1. Antihistamines (antiallergic) agents: tavegil, ketotifen, suprastin, Erius, Zyrtec or analogues.
2. In case of severe swelling or an acute and violent allergy attack, call an ambulance. The doctor will give an injection of a hormonal drug: prednisolone, dexamethasone or diprospan.
3. For stomatitis, rinse your mouth with a decoction of medicinal herbs (chamomile, oak bark). Lubricate ulcers in the mouth and lips with Kamistad, Cholisal, sea buckthorn oil, tetracycline ointment, potassium permanganate solution, chlorhexidine solution or 1% aqueous solution of methylene blue.
4. For skin lesions, apply ointment with zinc (for example, zindol, zinocap) to the damaged areas. Hormonal ointments help well: Akriderm, Triderm, Advantan.
5. Take sorbents: activated carbon, smecta, enterosgel or others.
6. Follow a general nonspecific hypoallergenic diet. It excludes citrus fruits, mushrooms, smoked foods, honey and many other foods that provoke exacerbation of the reaction. Alcohol is also excluded.

thanks for the info about Diprospan, on the third day I ran to the pharmacy (one capsule is enough). I took the injection and finally slept at night. Don’t expect a miracle right away, but it will be much easier. Reader of the website Pokhover.rf

Ketotifen is one of the antiallergic drugs.

Be sure to tell your doctor if you suspect an allergy to Zorex, as it can be difficult to diagnose. The doctor sees the result: stomatitis, toxicodermatitis, urticaria, exudative erythema multiforme, in especially severe cases - Stephen-Jones syndrome, Quincke's edema. But he doesn't know the reason. And the patient usually has no idea to suspect an anti-hangover drug in his troubles, because usually their composition is quite harmless: aspirin, soda, citric acid, succinic acid, and so on.

It seems to a person that most likely he was poisoned by low-quality alcohol or stale snacks - after all, he just drank the day before. Swollen eyes can easily be attributed to a hangover or a raised stye; if your lips are swollen, it probably means herpes. A doctor who has not previously encountered symptoms of an allergy to Zorex will also not be able to guess the cause: after all, an allergic reaction can be to anything. And if there are only one or two symptoms present, then determining what needs to be treated will be even more difficult.

Our readers never left the doctors with any diagnosis until they remembered that they had taken Zorex. One man suspected a sexually transmitted disease and blamed his wife for cheating for a long time until he got to the bottom of the reason.

But even after the correct diagnosis is made, medications will not help immediately. Be patient, the acute reaction will pass, but your appearance may suffer for a long time: sometimes spots on the skin last longer than a year. Those who are allergic to Zorex say that tanning helps hide spots. You can also visit a cosmetic surgeon.

If an allergic reaction occurs after drinking, and what exactly is unknown, then use the advice from our short instructions:

What to do if an allergy occurs after drinking alcohol. Infographics.

Indications for use of Zorex

According to the instructions, the drug is recommended in the following cases:

• Alcohol abuse and chronic alcoholism;
• Chronic and acute poisoning with organic or inorganic compounds of elements such as mercury, gold, arsenic, zinc, bismuth, antimony, chromium, copper, cadmium, nickel, cobalt;
• Treatment of alcohol withdrawal syndrome;
• Intoxication with cardiac glycosides.

Zorex Morning tablets are prescribed for headaches caused by alcohol withdrawal syndrome, mild or moderate pain syndrome of various origins, as well as elevated body temperature for adults and children over 15 years of age.

Price, special instructions

The disinfectant is sold in pharmacies without a prescription. The price of the drug is 450-500 rubles per pack of 2 capsules. Unused medicine is effective for 3 years if stored away from direct sunlight.

There is another dosage form of the drug Zodex. So, if the word “Morning” is written on the package after the name, then inside the box there are effervescent tablets. They quickly dissolve in water, reach the bloodstream, and perform a disinfection effect. Typically, this product is bought by people who have not calculated the dose of alcohol and are experiencing withdrawal symptoms (hangover).

Mode of application

In accordance with the instructions, Zorex is taken orally, without chewing, half an hour before meals, washed down with plenty of water. The dosage of the drug is 1 capsule twice a day for alcohol abuse for no more than one week. 1 capsule twice a day is prescribed for chronic alcoholism, the course of treatment is 10 days. In cases of poisoning with heavy metal salts or arsenic, it is necessary to take 300-1000 mg of Zorex per day for a week, divided into two or three doses.

Zorex Morning tablets, previously dissolved in a glass of purified drinking water, are taken orally. The dosage of the drug for children over 15 years of age and adults is 1-2 tablets every 4-8 hours (maximum 8 tablets per day), for a week as an analgesic, or for three days as an antipyretic.

Analogues at a similar price

If after taking Zorex a person does not feel better, he needs to choose a high-quality analogue. The most effective drugs include:

• Alkodez (Ukraine);
• Zinkteral (Israel);
• Polyfan (China);
• Milife (Russia);
• Sorbex (Ukraine).

All drugs are sold in pharmacies without a prescription, have a quality certificate, clear instructions, and a reasonable price. But when changing the medicine, make sure there are no contraindications.

Contraindications

According to the instructions, Zorex is contraindicated in the following cases:

• In case of hypersensitivity to the components of the drug;
• In case of severe kidney or liver diseases in the decompensation stage;
• With low blood pressure (with caution).

Zorex Morning is contraindicated for:

• Severe renal or liver dysfunction;
• Hemorrhagic diathesis;
• Hypersensitivity to the components of the drug;
• "Aspirin" asthma;
• Erosive and ulcerative lesions of the gastrointestinal tract;
• Pregnancy in the 1st and 3rd trimester and during lactation;
• Glucose-6-phosphate dehydrogenase deficiency;
• Portal hypertension.

The drug is also contraindicated in children under 15 years of age.

Side effects of Zorex

According to reviews, Zorex can cause nausea, tachycardia, dizziness and pale skin. In cases of drug overdose, lethargy, shortness of breath, stupor, hyperkinesis, short-term convulsions and lethargy occur.

According to reviews, Zorex Morning causes side effects from various body systems, namely:

• Tinnitus, headache, blurred vision, dizziness and deafness (CNS);
• Liver dysfunction, loss of appetite, gastralgia, diarrhea, vomiting, abdominal pain and nausea (digestive system);
• Agranulocytosis, thrombocythemia, aplastic anemia, pancytopenia, hypocoagulation, hemorrhagic syndrome and decreased platelet aggregation (hematopoietic system);
• Formation of urinary stones, renal failure, papillary necrosis, hyperoxaluria and damage to the glomerular apparatus of the kidneys (urinary system).

Also, according to reviews, Zorex Morning causes a number of allergic reactions, which include Quincke's edema, Lyell and Stevens-Johnson syndrome, skin rash and bronchospasm.

Does the instructions say about the dangers of allergies?

Yes. This is what is stated in the instructions for Zorex, in the “Side Effects” section:

“Rarely: allergic reactions (skin itching, urticaria, rash on the skin and mucous membranes, genital itching, stomatitis).

Very rare: the appearance of an allergic reaction such as angioedema or Steven-Johnson syndrome (sudden increase in body temperature, malaise, maculo-vesicular or bullous rashes on the skin, mucous membranes of the oral cavity, genitals, in the anus). In this case, you should stop taking the drug and consult a doctor.

The risk of developing allergic reactions is higher in people with bronchial asthma or a history of allergies.”

As we see, manufacturers warned about the possibility of side effects. Steven-Johnson syndrome means nothing to most of us, but it is the allergic reaction you see in photographs.

The instructions for medications include the following designations for the frequency of side effects:

• Rare - less than one case per thousand patients.
• Very rare - less than one case per ten thousand patients.

The editors of our site have no way to check whether such reactions really occur very rarely, because people who avoided the consequences write about it in the comments much less often.

Our readers claim that an allergy to Zorex can occur even in those who have never had an allergy to anything before. We also cannot confirm or deny these claims.

Our readers often tell this story about their relationship with Zorex. For the first time, it can help with a hangover without any complaints, and the delighted experimenter enthusiastically recommends this drug to his friends. The second time, after a completely different drinking session, a weak reaction to Zorex occurs, which can be easily tolerated: for example, the lips swell a little - but otherwise everything goes well. And then, after the third dose of the drug, suddenly such a strong and violent reaction occurs that the person curses the day when he first decided to try this remedy.