Very often, adult diseases affect children, but the drug used to treat a woman is not always suitable for a girl, especially in the case of sexually transmitted infections. They cannot be left untreated, but not everyone knows what to do in such a situation.
The medicine Polygynax Virgo relieves specific genital ailments in girls who do not have intimate relationships.
How does it work? Does it cause side effects? What is it effective against? - Let's look at it in more detail later in the article.
Pharmacodynamics and pharmacokinetics
Polygynax Virgo is a combined antibacterial and antifungal medication in a dosage form specially designed for use in pediatric gynecology .
The active ingredients of this drug have a bactericidal effect aimed at destroying pathogenic gram-positive bacteria (including corynebacteria, Staphylococcus aureus, etc.) and gram-negative microorganisms (including Enterococcus faecium, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Proteus vulgaris, Klebsiella pneumoniae, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Ureaplasma urealiticum).
Also, the complex of antibiotics included in the drug is characterized by a fungicidal effect against pathogenic fungal strains and is especially effective in the fight against yeast-like fungi of the genus Candida albicans ( thrush ), cryptococci and histoplasmas.
The use of Polygynax Virgo vaginal capsules not only productively resists the above-mentioned pathological pathogens of various diseases, but also helps to improve trophic processes in the vaginal mucosa.
When capsules are administered intravaginally, all the active ingredients of the drug are evenly distributed over the surface of the vaginal mucosa, where their local fungicidal and bactericidal effects are fully manifested.
Due to the local use of capsules, the absorption of their active ingredients from the vaginal mucosa into the systemic circulation occurs in minimal, insignificant volumes.
Features of good stagnation
In advance
Bacteriological investigations must be carried out before a drug is used. In cases of placental intolerance or allergic reaction, treatment should be taken.
Sensitization of the body with locally administered antibiotics may later lead to an allergic reaction with systemic administration of the same or controversial antibiotic.
Foreign calls at vikoristan
It is important to avoid the dangers of treatment through the risk of the emergence of resistant microorganisms and superinfections caused by these microorganisms.
The lack of data on the role of the resorption fraction of neomycin and polymyxin B through the mucous membrane does not allow us to completely exclude the risk of systemic effects, which especially increases in cases of nitric deficiency.
It is advisable to avoid soybean oil, which may cause hypersensitivity reactions (hypersensitivity, anaphylactic shock).
The medicinal form of the drug Polygynax Virgo is intended for administration to children and young girls.
Suspension during pregnancy or breastfeeding.
In cases of vaginosis in girls of the epithelium, administration of the drug may only be required by a doctor, if the measles for the vagitum is extracted and the potential sac for the fetus is outweighed. If you are careful about your vaginosis, if you recognize the influx of your doctor’s function, it is not enough to turn off any risk.
Due to the lack of data on the penetration of the drug into breast milk, congealing of this drug during breastfeeding is not recommended.
The importance of influencing the fluidity of the reaction during treatment with vehicles or other mechanisms
.
Doesn't flow in.
Indications for use
Polygynax Virgo vaginal capsules are indicated for use in pediatrics, namely in pediatric gynecology , for the treatment of cervicovaginitis ; fungal , nonspecific , mixed vaginitis and vulvovaginitis .
It is also practiced to use the drug for prophylactic purposes before performing diagnostic intrauterine procedures and performing surgical operations in the genital area.
Contraindications
Before administering Polygynax Virgo, a female child should make sure that she does not have personal hypersensitivity to any of the ingredients (active and auxiliary) of the drug, including the capsule shell, since such high sensitivity can lead to the formation of various, sometimes severe, allergic reactions . If a child has a sharp negative response to any substance included in the dosage form, the use of Polygynax Virgo capsules is strictly contraindicated.
Side effects
When carrying out treatment using Polygynax Virgo, the formation of allergic reactions , most often associated with hypersensitivity to the ingredients of the capsules.
With prolonged use of these vaginal capsules, the possibility of developing systemic negative side effects inherent in aminoglycosides , which may increase in cases of insufficiency of the patient's renal function .
Side effects
Possible development of contact allergic eczema, more often with prolonged dosing (intensities can spread far beyond the boundaries of the dosage of the drug); reactions of the mucous membrane, including redness, swelling, itching of the mucous membrane; allergic reactions, including anaphylactic shock, kropivyanka. There is a risk of toxic systemic effects (on the side of the eye, the organs of hearing) in the area after a short period of recommended therapy.
There may be a hypersensitivity reaction in patients to an additional substance - soybean oil.
Instructions for use
The official instructions for Polygynax Virgo allow the contents of the capsules to be administered exclusively intravaginally (inside the vagina). The recommended dosage regimen involves the use of 1 capsule daily after the evening toilet procedure, in anticipation of sleep.
For proper use of vaginal capsules, it is necessary to cut its pointed protruding tip and, by lightly pressing the capsule itself, insert the contents of the dosage form into the vagina. The capsule used in this way must be disposed of (thrown in the trash).
Both the therapeutic and prophylactic course of using the drug Polygynax Virgo usually takes 6 days (unless otherwise instructed by the pediatrician).
If it is necessary to skip the administration of an emulsion from one or more capsules, treatment is resumed at the usual recommended daily dose (1 capsule per 24 hours).
Method of congestion and dosage
It is necessary to cut the end of the capsule with scissors. Then, instead of 1 capsule, administer intravaginally, pressing firmly on the capsule, in the evening before bedtime, for 6 days after sleep.
Do not take bath during menstruation.
Be practical
The patient must be informed about hygiene (wearing extra whiteness, turning off douching and/or using tampons during bathing) and, as far as possible, identifying unfavorable factors that cause or getting sick.
special instructions
Polygynax Virgo vaginal capsules, containing an emulsion with active ingredients included in it, were specially developed for use in pediatric gynecology for the treatment of girls and adolescents.
During therapy, the patient should refrain from using intravaginal tampons (if used). There is no need to interrupt the therapeutic course during menstruation .
If a patient is diagnosed with renal failure , before starting treatment, you should consult a pediatrician, since this pathology may require a change in the dosage regimen.
The duration of use of the drug should be limited to the minimum effective period in order to prevent the emergence of resistance to its active ingredients in certain pathogenic pathogens , as well as to reduce the risk of possible reinfection .
Pharmacological authorities
Pharmacodynamics.
The power of the drug is obumovlenі with the powers that are attached to us, we will confine it to the warehouse. Neomycin sulfate is an aminoglycoside antibiotic that has a bactericidal effect by blocking the function of bacterial ribosomes in a wide range of gram-positive and gram-negative microorganisms: Corynebacterium spp., Staphylococcus spp., Mycobacterium tuberculus osis, Enterococcus faecium, Escherichia coli, Enterobacter aerogenes, Haemophilus influenzae, Klebsiella pneumoniae, Ptoteus vulgaris.
Polymixin B sulfate is an antibiotic of polypeptide nature, which is bactericidal and effective against gram-negative flora, especially
Pseudomonas aeruginosa
;
sensitive also include E. coli, Schigellae, Klebsiellae, Pasteurellae, Serratiae, Staphylococcus spp., Enterobacter, Salmonellae, Haemophilus, Bordetella
.
Polymixin B destroys the osmotic resistance of bacterial membranes, which are also active during the day and are in the dormant stage. Nystatin is a polyene antibiotic that is fungicidal or fungistatic by binding to ergosterol in the cytoplasmic membrane of fungi. Candida spp., Histoplasma spp., Coccidioides spp., Cryptococcus spp., Aspergillus, Blastomyces dermatidis
are active . Resistance to active substances of Polygynax Virgo rarely develops completely.
Dimethylpolysiloxane (dimethicone 1000), which is contained in the drug as a similar substance, is an organic semi-solid with a high molecular weight, which has enveloping power, to perform anti-inflammatory, reparative and anti-verbogenic action, paint є trophic processes in the mucous membrane of the meat, and also prevents the penetration of the active components into the drug in the mucous membrane.
Pharmacokinetics.
I didn’t fool around.
Analogs
Level 4 ATC code matches:
Ecofucin
Primafungin
Clindacin
Nystatin
Polygynax
- Dalatsin;
- Clindamycin;
- Natamycin;
- Vagitsin;
- Nystatin;
- Clindacin;
- Pimafucin;
- Sintomycin;
- Clindes;
- Milagin;
- Primafungin;
- Ecofucin;
- Neotrizol;
- Cervugid;
- Meratin;
- Terzhinan.
How to replace Polygynax Virgo
A direct analogue of Polygynax is the drug for adults Polygynax in the form of vaginal capsules. The medication in question can also be replaced with indirect analogues that match the original in terms of therapeutic effect. Such means include:
- Vagitsin;
- Dalatsin;
- Clindamycin;
- Klindes;
- Milagin;
- Natamycin;
- Pimafucin;
- Primafungin.
Reviews
Parents who have used this remedy to treat their children suffering from bacterial and/or fungal vaginal infections, the pathogens of which are sensitive to the active ingredients of the drug, almost all leave positive reviews about Polygynax Virgo. For children (girls and adolescent girls), this dosage form, namely capsules with vaginal emulsion, is ideal in terms of its uniform distribution over the entire mucous surface of the vagina and the effectiveness of its action, and in total with minimal absorption into the systemic bloodstream it is also relatively safe (compared to oral antibiotics ).
Who is the drug suitable for?
The instructions recommend using Polygynax Virgo for the treatment of inflammatory gynecological pathologies in children and adolescents. Before prescribing a medication, it is necessary to undergo an examination by a specialist and undergo laboratory tests that will allow you to accurately determine the type of causative agent of the disease.
Symptoms of the development of vulvovaginitis include the appearance of purulent discharge from the genital tract, burning, itching, redness and inflammation of the genitals. Treatment of the disease in girls should be started immediately to avoid inflammation becoming chronic.
Price, where to buy
The average price of Polygynax Virgo No. 6 is 500 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Polygynax Virgo capsules for intravaginal use.
introduction emulsion 6 pcs. Catalent France Beinheim S.A./Innotera Shuzi RUB 391 order
Pharmacy Dialogue
- Polygynax Virgo (cap. No. 6) Innotera Chouzy
RUR 442 order
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Pharmacy24
- Polygynax Virgo No. 6 candles Innotera Shuzi, France
185 UAH. order
