How to take Reduxin 15 mg to lose weight: instructions for use

What is Reduxin

Reduxin is a combined drug used in the treatment of certain degrees of obesity, which affects receptors and certain areas of the central nervous system and brain, causing a feeling of satiety. As a result, there is a decrease in food cravings.

The active ingredients also reduce blood glucose levels, which helps suppress appetite, reducing the risk of overeating.

Composition of Reduxin

There are several varieties of Reduxin: blue capsules have a low concentration of the active substance, blue capsules have a high concentration. Their composition:

Potential buyers should be aware that a doctor's prescription is required to purchase the drug.

Release form

The capsules are packaged in blisters of 30 pieces - these tablets are just enough for one month of treatment. They are also divided according to the concentration of the active substance - 10 or 15 mg. An important point: the manufacturer produces the product only in cardboard boxes; capsules in plastic jars are fake! The price of the drug varies from 900-1000 rubles to 3-4 thousand, it all depends on the number of capsules in the package: 10, 20 or 30.

pharmachologic effect

Sibutramine is the main active ingredient in weight loss capsules. Due to this, the drug has an effect on the central nervous system through primary and secondary amines or metabolites that reuptake the hormones serotonin, norepinephrine, and dopamine. This increases the activity of neurotransmitters located in synapses, which are responsible for the feeling of fullness, satiety, and a decrease in the need for food.

Microcrystalline cellulose acts as an enterosorbent - a substance that, when it enters the stomach or intestines, absorbs various toxic wastes and poisons, and then exits through the organs of the excretory system through defecation.

Pharmacokinetics and pharmacodynamics

After the drug is ingested, sibutramine is quickly absorbed from the gastrointestinal tract. Absorption is at least 77%. Sibutramine is biotransformed, resulting in the formation of two active metabolites (mono- and didesmethylsibutramine). The highest concentration of the substance in the body is observed 1.2 hours after administration. The highest concentration of metabolites is after 3-4 hours.

If Reduxin tablets were taken simultaneously with food, the maximum concentration of metabolites is reduced by 30%, and the period for achieving it is increased by three hours. Distributes quickly into tissue. Sibutramine binds to blood proteins by 97%, and metabolites by 94%. It is excreted mainly by the kidneys, the half-life of sibutramine is 1.1 hours, that of metabolites is 14-16 hours.

How to take Reduxin correctly to lose weight

Regardless of the concentration of the active ingredient, Reduxin is prescribed by a doctor and taken one capsule once a day. But you should know that the maximum allowed amount is 15 mg per day, and the general course of treatment is 3 months. To date, no serious cases of overdose have been identified, but judging by the reviews of patients on thematic forums, taking drugs at the prescribed rate often causes side effects!

When is it better to use: morning or evening? There are no clear recommendations on this matter, so it is better for everyone to choose the most convenient time for themselves with the help of a doctor. The capsule should be taken with a sufficient amount of water. It is advisable not to eat for at least 30-40 minutes after taking it.

Instructions for use

Reduxin should be taken only in the dosage prescribed by your doctor. Usually, Reduxin is started with a small dose of about 5-10 mg.

Pros and cons of use

The positive effect is explained by the effect on the body of the active substance – sibutramine, which:

• Helps reduce hunger, suppress appetite, reduce cravings for “forbidden” foods (fatty, flour, smoked, highly salty and sweet).
• Improves metabolism.
• Reduces weight, reduces waist and hips.
• Removes impurities, toxins, excess liquid.
• Reduces the amount of fat, prevents the formation of deposits around internal organs.

Does Reduxin really help you lose weight? Despite the fact that the active substance itself is effective, all the positive aspects of taking capsules are overshadowed by the huge lists of contraindications and side effects discussed below.

Course duration

The duration of the course is prescribed by the doctor, usually it is three months. If, after four weeks from the start of treatment, weight loss to at least two kilograms has not been achieved, then the daily dosage is usually increased to 15 mg. The drug should also not be resumed if the weight has returned after discontinuation of the capsules.

Between three-month courses it is necessary to take a break of at least 14 days, and the total duration of use should not exceed one year, since there is no laboratory research data confirming or refuting the safety and effectiveness of the drug in this case.

special instructions

Reduxin should be used only in cases where all non-drug measures for weight loss are ineffective - if the weight loss over 3 months is less than 5 kg.

Treatment with the drug should be carried out as part of complex therapy for weight loss under the supervision of a physician with practical experience in the treatment of obesity.

Complex therapy for obesity includes both changes in diet and lifestyle, as well as increased physical activity. An important component of therapy is to create the prerequisites for persistent changes in eating behavior and lifestyle, which are necessary to maintain the achieved weight loss even after drug therapy is discontinued. Patients need to change their lifestyle and habits as part of drug therapy in such a way as to ensure that the achieved weight loss is maintained after completion of treatment. Patients should be clear that failure to comply with these requirements will lead to repeated weight gain and repeated visits to their doctor.

In patients taking Reduxin, it is necessary to measure blood pressure and heart rate. During the first 3 months of treatment, these parameters should be monitored every 2 weeks and then monthly. If during two consecutive visits an increase in resting heart rate ≥10 beats/min or systolic/diastolic pressure ≥10 mmHg is detected, treatment should be discontinued. In patients with arterial hypertension, whose blood pressure is higher than 145/90 mmHg during antihypertensive therapy, this control should be carried out especially carefully and, if necessary, at shorter intervals. In patients whose blood pressure exceeded 145/90 mmHg twice during repeated measurements. treatment with the drug should be discontinued.

In patients with sleep apnea syndrome, blood pressure must be monitored especially carefully.

The simultaneous administration of drugs that increase the QT interval requires special attention. These drugs include histamine H1 receptor blockers (astemizole, terfenadine); antiarrhythmic drugs that increase the QT interval (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol); gastrointestinal motility stimulant (cisapride), pimozide, sertindole and tricyclic antidepressants. This also applies to conditions that can lead to an increase in the QT interval, such as hypokalemia and hypomagnesemia (see also the section “Drug interactions”).

The interval between taking MAO inhibitors (including furazolidone, procarbazine, selegiline) and the drug should be at least 2 weeks.

Although the connection between taking the drug and the development of primary pulmonary hypertension has not been established, however, given the well-known risk of drugs in this group, with regular medical monitoring it is necessary to pay special attention to symptoms such as progressive dyspnea (breathing difficulty), chest pain and swelling on foot.

If you miss a dose of the drug, you should not take a double dose of the drug at the next dose; it is recommended to continue taking the drug according to the prescribed regimen.

The duration of taking the drug should not exceed 1 year.

When taking sibutramine and other serotonin reuptake inhibitors together, there is an increased risk of bleeding. In patients predisposed to bleeding or taking drugs that affect hemostasis or platelet function, sibutramine should be used with caution.

Although there is no clinical evidence of addiction to sibutramine, the patient's history of drug dependence should be assessed and attention should be paid to possible signs of drug abuse.

Indications for use

A course of Reduxin is prescribed by a doctor based on an examination of the patient, collecting an anamnesis and studying tests. Capsules can be recommended by a specialist in the following cases:

in case of alimentary or primary obesity associated with diseases of the metabolism or endocrine system, hormonal imbalances, provided that the patient’s body mass index exceeds 30 (the norm for a healthy person is on average 20-26);

with the alimentary type of obesity, if the body mass index exceeds 27 and there are concomitant diseases caused by excess body weight - type 2 diabetes mellitus, lipid metabolism disorders, etc.

Reduxin is often recommended by a doctor if obesity is pathological and caused by metabolic disorders. In this case, standard weight loss methods do not produce results - but such cases are extremely rare. Usually the reasons why weight has stopped or does not decrease at all are quite prosaic - incorrect calorie counting, constant overeating and breakdowns, lack of physical activity. And in this case, no miracle drugs or capsules will help; the main weapon in the fight against excess weight should be proper nutrition in combination with psychotherapy of eating habits. You need to understand what led to the gain of extra pounds, learn to deal with difficulties, and love your own body.

Interaction

If Reduxin is combined with inhibitors of microsomal oxidation (including inhibitors of cytochrome P450 isoenzyme 3A4), there is an increase in the concentration of sibutramine metabolites in plasma with an increase in heart rate and an increase in the QT interval, which is clinically insignificant.

A number of drugs can speed up the metabolism of sibutramine: macrolide antibiotics, phenobarbital , carbamazepine , dexamethasone , phenytoin .

Please note that serious interactions may occur when taking multiple medications that increase serotonin levels in the blood at the same time.

serotonin reuptake inhibitors , a number of drugs for the treatment of migraine, antitussives, and potent analgesics.

Non-exposure to oral contraceptives has no effect.

Contraindications

List of contraindications for the use of Reduxin:

• individual intolerance, sensitivity or allergy to the components included in the composition - sibutramine, microcrystalline cellulose;
• the presence of organic causes of excess weight - congenital or acquired diseases that cause metabolic disorders, changes in hormonal levels;
• eating disorders caused by psychological factors - anorexia or bulimia;
• simultaneous use of MAO inhibitors - drugs used to treat alcoholism, depression and some other mental illnesses and disorders;
• use of drugs that affect the central nervous system (neuroleptics, antidepressants), as well as drugs to normalize sleep;
• benign prostatic hyperplasia;
• pheochromocytoma;
• schizophrenia, organic psychoses;
• adrenal tumor;
• excess production of thyroid hormones;
• glaucoma;
• diseases of the heart, congenital and acquired, blood vessels, veins;
• uncontrolled arterial hypertension;
• Gilles de la Tourette syndrome (generalized tics);
• disturbances in the functioning of the kidneys and liver;
• pregnancy, breastfeeding period;
• age under 18 and over 60.

Often, people do not even suspect that they have diseases, since many develop without pronounced symptoms, so it is strictly not recommended to use Reduxin without consulting a weight loss specialist.

Side effects

Taking the drug without a doctor's prescription can cause serious harm to the body and lead to side effects, which include:

• From the central nervous system: headaches, anxiety and irritability, dry mouth accompanied by loss or change of tastes, burning or tingling sensation in the extremities - paresthesia.
• From the cardiovascular system: increased blood pressure, increased heart rate (pulse), tachycardia.
• From the gastrointestinal tract: the appearance of constipation, nausea and heartburn after eating, loss of appetite.
• In isolated, individual cases, itching or rashes on the skin, cramps, pain in the abdomen and lower back may occur.

Most often, side effects occur in the first month of taking the drug. During this time, it is necessary to especially carefully monitor your well-being: measure your blood pressure and pulse, consume a sufficient amount of fiber and plant fibers to prevent constipation, and do not forget to drink water - at least 1.5-2 liters daily.

pharmachologic effect

Anti-obesity pills Reduxin act directly on the human nervous system, so the drug is dispensed only as prescribed by a doctor. Their action is aimed at suppressing hunger and reducing appetite. Thanks to this, the person losing weight reduces the number of snacks and the total amount of food consumed is reduced. Due to the effect of thermogenesis, energy consumption increases and calories are burned faster. In addition, metabolism accelerates, the level of glucose, cholesterol and lipids in the blood is normalized.

The described mechanism of action of Reduxin diet pills allows a person to effectively lose weight, while weight loss occurs at a safe speed (about 1 kg per week). However, taking anti-obesity medication can cause negative consequences in the form of side effects, so treatment should be carried out under the close supervision of a doctor.

Reduxin's analogs

Reduxin has several analogues - drugs that are similar in pharmacological properties, but differ in price, active ingredients and their dosage. Let’s take a closer look at the most common ones, but don’t forget that analogues should also be prescribed by a doctor.

When choosing capsules, experts pay attention to the concentration of the active substance and try to choose an analogue that is similar in effect.

Can it be used during pregnancy?

1. Reduxin is prohibited from use during pregnancy due to the lack of insufficient clinical studies on the safe effects of the active substance on fetal development.
2. Girls and women of childbearing age must additionally take contraceptives while using the medication.
3. It is also prohibited to take Reduxin during breastfeeding.

Instructions for use of Reduxin

The instructions for use are the same for each type of drug - one tablet daily. Let's take a closer look at the three main types of capsules for weight loss Reduxin.

How to take Reduxin 10 mg

10 mg is the standard dose for the drug Reduxin. It is prescribed from the very beginning, but adjusted as necessary, reduced or increased.

Reduxin 10 mg has the following similarities with other varieties:

• - identical pharmacological properties, indications for use, contraindications, side effects;
• - effectively reduce appetite, help in the fight against food addiction;
• - help normalize glucose levels and remove “bad” cholesterol.

It is impossible to unequivocally answer the question of which concentration is better: it all depends on individual indications.

How to take Reduxin 15 mg

Reduxin 15 mg is distinguished by a high, maximum possible concentration of active ingredients, which is used if smaller ones do not give the desired result.

But it should be understood that such a concentration can be fatal to the body:

• — since 2010, the use of sibutramine in the countries of the European Community has been suspended;
• - according to current legislation, since January 2004 in the Russian Federation sibutramine has been recognized as potent and hazardous to health;
• — the sale of sibutramine-containing drugs is permitted only in pharmacies with a special prescription, which is subject to special registration;
• — sibutramine is also included in the list of the World Anti-Doping Agency (2010), where it is classified as a substance prohibited during competitions.

Before you start taking any “diet pills,” you need to think about whether getting an ideal figure is worth the side effects? Moreover, modern weight loss specialists are ready to offer their patients individually developed methods that are completely safe for the body.

How to take Reduxin Light

Reduxin Light belongs to the category of biologically active additives - dietary supplements, so you can purchase capsules at any pharmacy, without special prescription from a specialist. They contain conjugated linoleic acid - the main active component, belonging to the group of essential amino acids that the body is not able to synthesize on its own, but receives from protein foods - meat, dairy products, beans.

• Stimulate the functioning of the immune system.
• They have a powerful antioxidant effect, rejuvenating the body.
• Improves metabolic processes.
• Slow down the processes of fat deposition in subcutaneous fat.
• Promotes muscle growth during intense strength training.
• Act as a measure to prevent cardiovascular diseases.

There will be no great harm or side effects from such a biological additive, but you shouldn’t expect huge benefits either. Reduxin Light acts as a vitamin-mineral complex, nothing more. It is better, again, to entrust the choice and prescription of this dietary supplement to a doctor.

Real reviews about reduxin for weight loss

Olga, 26 years old: After the birth of my second child, my weight began to rapidly gain until I reached 87 kg with a height of 165 cm. As a young mother, I could not find time for myself, prepare a menu according to a diet plan, go to training regularly - all this is not for me. And I wanted to lose weight. Having seen enough promising “before and after” photos, I ran to the pharmacists at the nearest pharmacy. They didn’t sell me the drug, but they offered it a lighter version - Light. I took exactly the course and paid almost five thousand for it. What's the result? No. Wasted time, that’s why I give Reduksin the lowest score, I won’t recommend him.

Oleg, 45 years old: All my life I had a tendency to be overweight, over time the extra pounds kept adding and adding. The result is the second stage of obesity, accompanied by type 2 diabetes. It was not easy to go through the rehabilitation course on my own; I was constantly drawn to products from the “strictly prohibited” list. On one of the thematic forums, I found an interesting discussion about Reduxin, where they praised its positive aspects, and most importantly - complete control over appetite! I got it and tried it. During the first month, I really didn’t want to eat, but this was due to strong side effects. I was shivering, severe tachycardia developed, and shortness of breath appeared. I had to stop taking the capsules. And the kilograms lost during the month of torment came back with interest.

Katerina, 56 years old: due to age-related changes, I became the unfortunate owner of several extra pounds, which brought with it problems with blood pressure and heart. Doctors were unanimous: it is necessary to get rid of unnecessary volumes, because they are the main cause of illnesses. Having decided to fight the problem quickly and decisively, I purchased Reduxin capsules. In the first weeks of treatment, there was a huge surge of strength - it was nervous excitement, I went outside to walk more and spend energy. In the evenings I couldn’t sleep for a long time. Tension, as if the brain would explode, sometimes there was anxiety. Over time, such symptoms began to scare me, I had to turn to specialists, who recommended stopping taking the drug in order to undergo a comprehensive clinical examination, restore the body, and the energy spent.

Overdose

There is currently no sufficient data on sibutramine overdose. In case of overdose, it is important to immediately contact a specialist. If you take too much of the drug, side effects may increase. There is no information about specific signs of overdose.

If you take excessive doses of the drug, you need to take activated charcoal and rinse your stomach. Symptomatic treatment is carried out. If after an overdose the patient's blood pressure increases or tachycardia is noted, it is advisable to prescribe beta-blockers.

Expert opinion

The drug is very difficult. By the way, it has long been prohibited in enlightened Europe, and this is not a good argument against (in terms of life safety, we will not be equal to third world countries, where street dealers can give back drugs). A number of studies have proven the presence of serious risks when using Reduxin: its work can undermine not only the heart, but also the brain, and even deaths have been noted more than once...

Yes, Reduxin has many contraindications. Those that are known at the moment are listed in the instructions. But this, again, is information not for you, but for your doctor. In the world of medicine and drugs, it is not for you to decide what is possible and what is not. Unless you're suicidal, of course.

Well, as for its importance for losing weight - how can I tell you more precisely... losing weight and getting healthier are not the same thing. Diseases not only make you fat, they can also make you dry out. Do you need to lose pounds at any cost - or just get healthy and get back to normal? This is fundamentally a choice, and not the same thing. Just because you've lost weight doesn't mean you've become healthier. Very often it's just the opposite. So you don’t have to strive to lose weight, you have to strive for health!

You can look at the question from this point of view: natural, natural is always better than artificial, “chemicalized”. Won't you argue? Have you read about modern ecology and all that? Now just compare: what do you think is more natural, more reliable, more healing - a common human habit that a psychotherapist will form for you with simple conversations without any medications, or chemistry, which will artificially and unregulatedly suppress your appetite, affecting the delicate nerve centers in some way? then poisons with a list of side effects that is still unknown?