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Tiloron is an antiviral immunostimulating drug. Belongs to the group of antiviral drugs for systemic use - other antiviral drugs (J05AX).
Active ingredient: Tilorone dihydrochloride. Bioavailability is 60%, and the half-life is 48 hours. The drug Tiloron is available without a doctor's prescription!
Composition and dosage forms
Tiloron tablets are an immunostimulating agent that actively fights the introduction and spread of viruses into the human body. The release form and composition of the medication are reflected in the instructions for its use. This drug contains the main active ingredient called tilorone dihydrochloride.
There are two known dosage forms of this drug:
- Tablets that have a surface coating with a special protective coating. The core of the drug consists of a substance with an orange tint. Tablets can be on blisters, their number varies from 6 to 30 pieces. Each tablet contains 60, 125 mg of tilorone dihydrochloride, as well as a number of auxiliary components (cellulose, lactose, magnesium stearate, macrogol and others).
- Capsules in a gelatin shell containing granules and orange powder inside. The instructions describe the composition of the 150 mg capsule as follows: 125 mg of tilorone, as well as auxiliary calcium stearate, cellulose, gelatin, dye, copovidone, titanium dioxide.
Which is better: Tiloron or AMIXIN
AMIXIN.
Photo: uteka.ru Both drugs are analogues of each other. Active ingredient: Tiloron. Available in dosages of 60 mg and 125 mg. They differ in the content of auxiliary components. Available without a doctor's prescription.
The drugs are produced in Russia. AMIXIN is cheaper in cost than Tiloron. Price per package from 544 rub.
pharmachologic effect
The pharmacological properties of Tiloron include the ability to fight viruses, as well as stimulate the immune system. The drug belongs to the group of synthetic low-molecular interferon inducers.
Tiloron stimulates the production of interferons of different types (alpha, gamma, beta, lambda) by such objects as intestinal epithelial cells, granulocytes, neutrophils, hepatocytes, T-lymphocytes.
Oral administration of the drug quickly leads to maximum induction of protective antibodies. First they appear in the intestines, then in the liver and, a little later, in blood cells. The first interferons begin to be produced within 4 hours, the last ones, a day after using the drug.
A single daily dose of Tiloron leads to the appearance of the maximum amount of lambda interferons in the lung tissues within 24 hours. Alpha interferons are fixed after 2 days. Both types of protective antibodies increase the body's ability to defend against viral effects, which is very important during the spread of influenza and other viral respiratory infections.
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Tiloron features:
- synthesis of interferon by leukocytes of the human body;
- stimulation of brain stem cell activity;
- enhancing the formation of antibodies that can reduce the level of immunosuppression and restore equality in the number of existing T-suppressors and T-helpers;
- inhibition of the translation of viral proteins in the cellular structure, which stops the reproduction of viruses.
The medication is highly effective against various infections:
- herpes;
- flu;
- parainfluenza;
- hepatitis;
- rhinovirus;
- adenovirus;
- syncytial infection;
- other ARVI.
After capsules or tablets penetrate the gastrointestinal tract, their rapid absorption by the intestinal walls can be observed. The bioavailability of the active substance is at the level of 60%, and about 80% of the drug is bound to blood proteins.
The time taken for the drug to not be completely eliminated from the body is two days. This process occurs through the intestines, through which 70% of the drug is released, and through the kidneys (about 9% of the substance).
Tiloron does not have the ability to accumulate in the body; it is also not subject to biotransformation.
Indications and contraindications
Indications for use of Tiloron are as follows:
- hepatitis types A, B, C caused by viral exposure;
- herpes viruses of the first two types;
- cytomegalovirus;
- encephalomyelitis (only for complex therapy);
- chlamydia, which affects the genital and respiratory organs;
- flu;
- ARVI (therapeutic and preventive effects).
It is not allowed to use Tiloron at your own request. This drug should only be prescribed by a qualified specialist who can adequately assess the possibility of therapy with this medication in a particular person.
Each medicine has a list of indications when its use is prohibited.
Contraindications to the use of Tiloron:
- lactose intolerance (congenital, hereditary or acquired);
- lactase deficiency;
- malabsorption of glucose and lactose;
- pregnancy status;
- period of breastfeeding;
- children under seven years of age;
- people who have a high personal sensitivity to the components of the drug.
The instructions for the drug emphasize that its use as a therapeutic and prophylactic agent in the presence of various viral diseases is possible only under close medical supervision.
Which is better: Tiloron or Ingavirin
Ingavirin.
Photo: 6030000.ru The drugs are not analogues of each other. Active ingredient: Tilorone dihydrochloride. Release form: tablets and capsules in dosages of 60 mg and 125 mg for oral administration. Ingavirin is an antiviral drug with the active component imidazolylethanamide pentanedioic acid (vitaglutam) in dosages of 30 mg, 60 mg and 90 mg. Available in the form of capsules for oral administration. Ingavirin indications:
- treatment of influenza A and B and other acute respiratory viral infections (adenoviral infection, parainfluenza, respiratory syncytial infection) in adults;
- prevention of influenza A and B and other acute respiratory viral infections in adults.
Both drugs are approved for use in pediatrics from 7 years of age. Dispensed without a doctor's prescription!
The drugs are produced in Russia. Ingavirin is cheaper in cost than Tiloron.
Dosage of the drug
The method of using Tiloron is clearly described in the instructions that are included with each package of the drug. This drug is to be taken orally; it is advisable to take tablets or capsules after meals.
Dosing features depend on the nature and type of disease for which it is used:
- treatment of viral infections, including influenza: on days 1 and 2 you should take one tablet per day (with a dose of 125 mg), then on days 3 and 4 there will be a break, after which the patient receives one tablet. This is followed by a two-day break and the use of one tablet;
- prevention of the development of a cold caused by a virus: the drug should be taken one tablet once a week for 1.5 months;
- hepatitis A: the first day the patient receives 125 mg every day, then 125 mg every 2 days. You should drink 1250 mg per course;
- hepatitis B (acute form): the first day the patient drinks 1 tablet, then after 2 days - one tablet per day. The course is 2000 mg;
- hepatitis B (protracted form): the same dosage regimen, you need to take 2500 mg of the drug per course;
- hepatitis B (chronic form): first take one tablet in the first two days, two days later take another tablet; then take 125 mg once a week. During a course of treatment, the patient can receive from 3750 to 5000 mg, the duration of therapy can vary from 3, 5 to 6 months (here you need to take into account the totality of biochemical, clinical, morphological and other indicators);
- hepatitis C (acute form): the first and second day, one tablet, after two days one tablet. Get 2500 mg per course;
- hepatitis C (chronic form): first the patient takes a tablet on the first and second days, then a tablet at a two-day interval, then a tablet at a weekly interval. It is recommended to take 5000 mg of medication per course; the duration of therapy can be six months. All this time, monitoring of clinical indicators is required;
- cytomegalovirus, herpes: standard dosage per tablet on days 1 and 2, then a 48-hour interval and one tablet. The course of treatment ranges from 1250 to 2500 mg;
- tuberculosis: days 1 and 2, 2 tablets per day, one tablet at a two-day interval. The total dose of the drug is 2500 mg;
- chlamydia (damage to the respiratory or genital organs): 1st and 2nd day one tablet, every 48 hours one tablet. The course is 1250 mg;
- encephalomyelitis (viral, infectious-allergic): the first 2 days, 1 or 2 tablets per day, then, after two days - one tablet. The course of therapy can last a month.
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Special instructions:
- The instructions do not contain comprehensive data on the effect of the drug on the reaction rate, so the patient can take the medicine while simultaneously driving a vehicle and working with complex instruments.
- High doses of Tiloron are prohibited due to the high risk of short-term depletion of immune cells.
Analogs
Structural analogues include: Activiron, Amiksin, Lavomax, Tilaksin, Tiloram. The drug Tiloram is an analogue often prescribed to patients as a replacement for Tiloron. Without accumulating in the body, Tiloram tablets also do not undergo biotransformation and are eliminated within 48 hours. The high compatibility of the components of the drug with other forms of drugs allows Tiloram to be used in the treatment of viral infections of various etiologies.
The differences are in expiration dates and price:
- Tiloron is good for 2 years, the price starts from $10 and is not often found in pharmacies.
- Tiloram is good for 3 years, starts at $8, and is a popular over-the-counter drug.
Pharmacy kiosks mainly offer Tiloram Ozone; the instructions for use do not recommend treatment for children under 18 years of age. Basically, the restrictions, release form and indications are identical to those presented above. The price of the drug is from $11.
Side effects
Side effects and contraindications to the use of the drug are reflected in the instructions included with each package. As a rule, patients tolerate such therapy quite comfortably; very rarely some negative manifestations may develop.
Side effects:
- allergic rash;
- chills that occur for a short time;
- development of dyspeptic disorders.
There have been no cases of Tiloron overdose recorded in medical practice.
Compatibility with other drugs
Tiloron is recommended by specialists for use as part of complex therapy. It can be combined with antibacterial compounds, as well as other symptomatic medications, often used to alleviate the condition of patients with viral and bacterial infections.
There are analogues of this drug on the pharmaceutical market:
- Amiksin;
- Aktavin;
- Lavomax;
- Tiloram;
- Tilorone dihydrochloride.
Only a specialist with sufficient qualifications and the ability to assess the benefits and risks of using the medication in a particular person can select a drug suitable for treating or preventing the development of a viral infection.
Despite the fact that Tiloron has high antiviral activity, using it alone to prevent the development of viral infections is, to say the least, ineffective. To prevent infection, it is very important to adhere to reasonable preventive measures, avoid crowded places, and also observe personal hygiene rules.
We recommend reading: Common Anaferon Analogues
Which is better: Tiloron or LAVOMAX
LAVOMAX tablets.
Photo: nebolet.com The drugs act as analogues of each other. The active component of the drugs is Tilorone dihydrochloride. The antiviral drug Tiloron is available in the form of tablets and capsules for oral administration; LAVOMAX is produced only in the form of tablets for oral use. The composition of excipients differs. Both drugs are approved for use from 7 years of age. Over-the-counter holiday!
The drugs are produced in Russia. LAVOMAX is cheaper in cost than Tiloron.
