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Manufacturers: BIOTICS MNPK
Active ingredients
- Pyridoxine
- Threonine
Disease class
- Mental and behavioral disorders caused by alcohol consumption - dependence syndrome
- Mental and behavioral disorders caused by alcohol consumption - withdrawal state
- Other neurotic disorders
- Irritability and anger
Clinical and pharmacological group
- Not indicated. See instructions
Pharmacological action
- Anti-withdrawal (anti-alcohol)
- Anti-alcohol
- Metabolic
- Neuroprotective
Pharmacological group
- Means for correcting disorders of alcoholism, toxicity and drug addiction
- Vitamins and vitamin-like products in combinations
Pharmacological group
The main active ingredient of the drug L-threonine in the presence of vitamin B6 is converted into the amino acid glycine and acetaldehyde. The compounds enhance the course of inhibition processes and at the same time improve redox reactions, intracellular respiration and the synthesis of high-energy compounds (ATP). Due to this, several effects are realized:
- Improving short-term and long-term memory.
- Normalization of the level of endogenous (own) acetaldehyde, thereby easing the state of withdrawal.
- Reducing psycho-emotional stress.
- Improved mental performance.
The drug has anti-alcohol, anti-withdrawal, neuroprotective and metabolic effects, which develop within 10-20 minutes after sublingual administration of the tablet. The active substances are quickly absorbed from the oral mucosa into the systemic bloodstream, penetrate into the structures of the central nervous system, where they are included in metabolism and have therapeutic effects.
Sublingual tablets Biotredin
Instructions for medical use of the drug
Description of pharmacological action
Affects tissue metabolism, increases mental performance, and has a therapeutic effect in alcohol withdrawal syndrome. L-threonine, in the presence of vitamin B6, breaks down into the amino acid glycine and acetaldehyde, which stimulate inhibition processes and redox reactions, respiration processes and ATP synthesis in cells, thereby achieving: reducing psycho-emotional stress, improving short-term and long-term memory, mood and concentration attention, normalization of the content of endogenous acetaldehyde (due to which the phenomena of alcohol withdrawal syndrome and craving for alcohol are reduced). The effect of Biotredin appears 10–20 minutes after sublingual administration.
Indications for use
- decreased mental performance and concentration in adults, adolescents and children; — alcohol abuse and chronic alcoholism; with pathological craving for alcohol, accompanied by affective (irritability, decreased mood, internal discomfort), sensory (feelings of hunger) and ideational (thoughts about alcohol) disturbances; - alcohol withdrawal syndrome, to maintain remissions in alcoholism.
Release form
sublingual tablets 5 mg + 100 mg; contour packaging 50, cardboard pack 1; sublingual tablets 5 mg + 100 mg; contour packaging 30, cardboard pack 1; sublingual tablets 5 mg + 100 mg; contour packaging 30, cardboard pack 2; sublingual tablets 5 mg + 100 mg; contour packaging 50, cardboard pack 2; Composition Sublingual tablets 1 table. L-threonine 0.1 g pyridoxine hydrochloride 0.005 g excipients: povidone (low molecular weight PVP), citric acid; magnesium stearate in blister packs 30 or 50 pcs.; in a cardboard pack 1 package.
Pharmacodynamics
Affects tissue metabolism, increases mental performance, and has a therapeutic effect in alcohol withdrawal syndrome. L-threonine, in the presence of vitamin B6, breaks down into the amino acid glycine and acetaldehyde, which stimulate inhibition processes and redox reactions, respiration processes and ATP synthesis in cells, thereby achieving: reducing psycho-emotional stress, improving short-term and long-term memory, mood and concentration attention, normalization of the content of endogenous acetaldehyde (due to which the phenomena of alcohol withdrawal syndrome and craving for alcohol are reduced). The effect of Biotredin appears 10–20 minutes after sublingual administration.
Pharmacokinetics
L-threonine and vitamin B6 are completely metabolized to water and carbon dioxide and do not accumulate in the body.
Use during pregnancy
Can be used during pregnancy and breastfeeding.
Contraindications for use
- state of alcoholic intoxication; - simultaneous use of anxiolytics, neuroleptics, antidepressants.
Side effects
Dizziness, increased sweating.
Directions for use and doses
Sublingually (in the form of a tablet or powder after crushing the tablet), to increase attention and mental performance: children - 2 mg/kg, adolescents and adults - 1 tablet. 2-3 times a day for 3-10 days. If necessary, the course is repeated 3–4 or more times a year. For the treatment of chronic alcoholism - 1-3 tables. 2–3 times a day for 4–5 days. If necessary, the course is repeated up to 5–10 times a year. For the treatment of alcohol withdrawal syndrome - on the first day - 1-4 tablets. 3-4 times a day (daily dose - 3-16 tablets), then 1-2 tablets. 2-3 times a day (daily dose - 3-6 tablets) for 21-28 days. The course can be shortened to 10–14 days. The greatest effect of Biotredin is achieved when combined with glycine - 1 table. sublingually 10–15 minutes before taking Biotredin. During the period of remission, to identify a hidden craving for alcohol, take 2-3 tablets. on an empty stomach. The appearance within 10–20 minutes of slight dizziness, a calming effect, redness of the face, and sweating indicate the presence of hidden attraction. In these cases, a 5-10-day course of Biotredin, 1-2 tablets, is recommended. 2–3 times a day (in combination with Glycine, 0.1 g sublingually 10–15 minutes before taking Biotredin).
Overdose
Not identified.
Special instructions for use
It is not recommended to use in a state of intoxication (as the therapeutic effect of the drug is reduced).
Storage conditions
List B.: In a dry place, protected from light.
Best before date
36 months
ATX classification:
A Digestive tract and metabolism
A11 Vitamins
A11J Vitamins in combination with other drugs
A11JC Vitamins in combination with other drugs
Indications for use
The main medical indication for taking tablets is to improve the functional state of the structures of the central nervous system in adults and adolescents with a decrease in concentration, as well as during the treatment of withdrawal syndrome in chronic alcoholism.
for adults
For adults, the drug is used to increase concentration and mental performance against the background of various pathological processes or fatigue.
The medication is used by people with chronic alcoholism to actualize the craving for drinking alcohol, which is accompanied by affective disorders (aggression, increased irritability, internal discomfort, worsening mood). The drug is indicated for alcohol withdrawal syndrome, as well as for identifying and treating hidden cravings for alcohol.
for children
The medicine can be prescribed to adolescents over 15 years of age to improve the functional state of the central nervous system, increase concentration, and mental performance.
for pregnant women and during lactation
The medication is contraindicated for use by pregnant and breastfeeding women.
Contraindications
There are a number of medical contraindications, in the presence of which the patient is excluded from using the drug:
- Simultaneous use of drugs that have a suppressive effect on the structures of the central nervous system (antidepressants, antipsychotics, anxiolytics).
- State of alcoholic intoxication.
- Hypersensitivity to any of the components of the drug.
- Pregnancy and lactation (except for cases of chronic alcoholism, in which the intake of alcohol into the body of a pregnant woman causes significant harm to the fetus).
Applications and dosages
The tablets are intended for sublingual use. They are placed under the tongue until completely dissolved, regardless of food intake. It is possible to crush the tablet into powder, which is then placed under the tongue. In this case, faster dissolution and absorption of the active components into the systemic circulation occurs.
for adults
The average therapeutic dose of the drug for adults depends on the indications:
- Increasing mental performance - 1 tablet 2-3 times a day, the course of treatment lasts from 3 to 10 days. If necessary, it is repeated 3-4 times a year.
- Alcohol abuse, chronic alcoholism – 1-3 tablets 2-3 times a day for a course of 4-5 days. If necessary, the course of treatment is repeated 5 to 10 times a year.
- Alcohol withdrawal syndrome - on the first day, 1-4 tablets are prescribed 3-4 times a day, then they switch to a maintenance dose, which is 1-2 tablets 2-3 times a day. The average course of treatment is 21-28 days. The duration can be reduced to 10-14 days.
A higher effectiveness of the drug is achieved when used simultaneously with glycine (tablets with a dosage of 100 mg). It is usually taken 15-20 minutes before the Biotredin tablet is dissolved.
for children
In adolescence, the medicine is used to normalize the functional state of the structures of the central nervous system, if necessary, increase concentration and mental performance, 1-2 tablets 2-3 times a day for several days. If necessary, the course of treatment is repeated 3-4 times a year.
for pregnant women and during lactation
The medicine can be used for pregnant and breastfeeding women suffering from chronic alcoholism for strict medical reasons. In this case, the dosage is determined individually by the attending physician.
Directions for use and dosage:
The drug is prescribed in tablets under the tongue or in powder form after crushing the tablet.
- As a means of increasing attention and mental performance: children, adolescents and adults, 1 tablet. 2-3 times/day for 3-10 days. If necessary, the course is repeated 3-4 times or more per year.
- Patients with chronic alcoholism and alcohol abusers are prescribed 1-3 tablets. per dose 2-3 times/day for 4-5 days. If necessary, courses are repeated 5-10 times a year.
- When treating alcohol withdrawal syndrome, 1-4 tablets are prescribed on the first day. 3-4 times/day (daily dose 3-16 tablets), on the second day and then 1-2 tablets. per dose 2-3 times a day (daily dose 3-6 tablets) for 21-28 days. The duration of the course can be shortened to 10-14 days.
The greatest effect of Biotredin is achieved when combined with the drug Glycine (100 mg tablet). Glycine is taken under the tongue 10-15 minutes before taking Biotredin.
- During the period of remission, to identify a hidden craving for alcohol, take 2-3 tablets. Biotredina® on an empty stomach. The appearance of mild dizziness, a calming effect, facial redness, and sweating within 10-20 minutes indicates the presence of “hidden cravings.” In these cases, a 5-10 day course of Biotredin® is recommended, 1-2 tablets. 2-3 times a day together with Glycine 100 mg sublingually 10-15 minutes before taking Biotredin®.
special instructions
Before you start using the medication, you should definitely pay attention to several special instructions:
- It is not recommended to take tablets while intoxicated, as this significantly reduces their therapeutic effectiveness.
- For pregnant and breastfeeding women, the medicine is prescribed only for strict medical indications, in particular for chronic alcoholism. This is due to the fact that the harm to the fetus from alcohol is significantly higher.
- During the course of drug treatment, it is recommended to refuse to perform potentially dangerous work that requires sufficient concentration of attention and speed of psychomotor reactions.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Biotredin, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Biotredin is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Analogs
There are no structural analogues for Biotredin tablets on the modern pharmaceutical market. There are drug substitutes that have similar therapeutic effects.
Colma
A drug used in the complex treatment of alcoholism. It is available in the dosage form of drops for oral administration. The drug is used for adults. It is not used in pediatric practice, and is also contraindicated in pregnant and breastfeeding women.
Antakson
The drug is prepared in capsule dosage form for oral administration. It has the ability to competitively bind opiate receptors in the structures of the central nervous system, thereby reducing the feeling of euphoria after taking psychoactive substances. Antakson is intended for adults for complex treatment of opiate and alcohol addiction. It is contraindicated for children, women during pregnancy, and also during breastfeeding.
