Instructions
The instructions contain information about indications, contraindications, taking the drug during pregnancy, drug interactions, and side effects.
You need to familiarize yourself with this information. This will help avoid unpleasant consequences.
Indications
The drug Metacin is prescribed for conditions such as:
- Smooth muscle spasms;
- Colic, gastritis, ulcer;
- Hypersecretion of salivary as well as bronchial glands;
- For pain in the abdomen that is unidentified.
In addition, Metacin can be prescribed during pregnancy to increase the excitability of the uterus (prescribed if there is a threat of miscarriage), as well as for premedication during cesarean section.
Application
Only a doctor can select the required dosage, as well as the duration of treatment.
The tablets should be taken orally with plenty of water. The dosage is 4 mg. The reception is divided into 3 times. A single dose is 5 mg, and the maximum is 15 mg.
The solution can be administered intravenously, intramuscularly, and also subcutaneously. The dosage is 0.5 - 2 ml. No more than 6 ml should be administered per day.
If the patient experiences side effects, the dosage should be reduced.
For mild and moderate hepatic and renal failure, the drug can be prescribed with caution. In severe cases of liver and kidney failure, this medication should be discontinued.
Release form
The medicine is available in the form:
- Tablets;
- Solution for the preparation of injections (available in ampoules).
The drug Metacin contains metocinium iodide.
Interaction
When taking Metacin together with m-anticholinergic blockers or any other drugs that have anticholinergic activity, an increase in anticholinergic effects may occur.
Contraindications
When is it better to refuse the help of this remedy? The use of the drug is contraindicated in the presence of hypersensitivity to one of the active substances. In addition, its use is not recommended for chronic lung diseases, paralytic intestinal obstruction, liver and kidney failure. Autonomic neuropathy, myasthenia gravis and urinary retention, as well as a predisposition to this disorder, are clear contraindications.
The instructions indicate that it is recommended to take the drug with extreme caution in the presence of heart disease, gastrointestinal pathologies, or elevated temperature.
Side effects
While taking this medication, the patient may experience side effects, which include conditions such as tachycardia, urinary retention, dysphagia, thirst, paralysis of accommodation, dry mouth, dilated pupils, and constipation.
In case of overdose, symptoms such as dry mouth, constipation, arrhythmia, and difficulty urinating are noted. When these conditions occur, the drug must be discontinued. Next, treatment should be carried out using anticholinesterase drugs.
Contraindications
Metacin is not recommended for use in cases of allergy to methocinium iodide.
This medicine is prescribed with caution for diseases and conditions such as:
Heart diseases in which an increase in heart rate is undesirable, for example, ischemic heart disease, hypertension, arrhythmia, stenosis, heart failure (chronic form);- Reflux esophagitis, thyrotoxicosis;
- Gastric hernia;
- Alahaz, pyloric stenosis;
- Paralytic ileus;
- Ulcerative colitis;
- Liver and kidney failure;
- any form of glaucoma;
- Any lung diseases that are chronic;
- Neuropathy, myasthenia gravis, gestosis;
- Urinary retention.
In addition, the drug Metacin should be prescribed with caution when treating disorders in children, especially for:
- In case of any brain damage;
- Down's diseases;
- Central paralysis in young children.
During pregnancy
Metacin is actively used during pregnancy, because improves blood circulation and also eliminates the threat of miscarriage or premature birth.
In case of a threat of miscarriage, which was accompanied by changes in the cervix, treatment with this medicine showed less effectiveness, however, it nevertheless made it possible to prolong pregnancy until a time that was safe for childbirth.
In the course of the research, some advantages were highlighted:
- Pregnant girls tolerated this medicine well;
- The drug Metacin does not have a negative effect on the fetus;
- Pregnant women extremely rarely experienced side effects, even if we were talking about long-term use;
- The medicine effectively helps with the threat of miscarriage.
While breastfeeding, you can use the drug Metacin, however, you need to constantly monitor the baby's reaction. If the baby begins to be capricious after feeding or sleeps poorly, then you should stop taking the medicine.
About the drug
"Methacin" is an effective drug that has a pronounced antispasmodic effect.
The active ingredient is metacinium iodide. This substance affects the contractile activity of muscle organs, blocks excessive nerve impulses and relieves tension from the smooth muscle tissues of not only the uterus, but also the esophagus, stomach, intestines, and biliary tract, therefore it can be used in obstetrics and gynecology, as well as in pulmonology and gastroenterology . With increased tone during pregnancy, Metacin has the following effects:
- Reduces the frequency of uterine contractions, reduces their duration and intensity.
- Improves uteroplacental blood circulation.
- Smoothes and relaxes the smooth muscles of the organ.
During treatment with Metacin, the risk of spontaneous miscarriage gradually decreases and disappears. At later stages, the drug removes the threat of premature birth and improves blood flow from mother to child.
Form
The drug is available in two dosage forms:
- Metacin solution for intramuscular, intravenous or subcutaneous injections. The cardboard package contains 10 ampoules and instructions for use. One ampoule contains 1 ml of solution.
- Metacin tablets. Packed in blisters with cells of 10 pieces each, sold in cardboard boxes with instructions.
Compound
Each tablet contains 2 mg of methocinium iodide as the active ingredient, as well as auxiliary elements:
- milk sugar;
- kahmal;
- magnesium stearate.
These substances enhance and complement the effectiveness of methocinium iodide and give the medicine a form that is convenient for administration. One ampoule contains 1 ml of solution, which contains 1 mg of active substance and water for injection.
Indications
Why is this drug prescribed? Metacin is used to relieve muscle spasms in the following cases:
- Peptic ulcer of the stomach and duodenum.
- Chronic gastritis.
- Renal, biliary and hepatic colic.
- Unspecified pain in the abdominal area.
- Hypersecretion of the bronchial and salivary glands.
During pregnancy, Metacin is prescribed only by a doctor, taking into account the severity of symptoms and the general condition of the patient.
Effective for:
- threat of early miscarriage due to uterine hypertonicity;
- threat of premature birth in the second half of pregnancy;
- the need to prolong gestation until a period that is safe for the child;
- premedication during caesarean section.
Experts point out that in case of increased uterine tone, self-medication with Metacin and other medications is unacceptable, as this can lead to fetal death and termination of pregnancy.
Storage
The drug Metacin should be kept away from small children and pets.
The drug should be stored in a dry place out of direct sunlight. In addition, the temperature in this place should be room temperature.
If all conditions are met, the shelf life of tablets should not exceed 5 years , and ampoules - 1 year. Once the product's expiration date has expired, its further use is prohibited. The drug Metacin must be disposed of.
Price
You need to find out the exact price for the drug Metacin in pharmacies in your city. This is due to the fact that the cost may vary significantly in different cities. In addition, the price is different in Ukraine and Russia.
Russia
- For the tablet form of the drug Metacin, you will have to pay on average 148 rubles;
- For injection ampoules in Moscow pharmacies you will have to pay 220 rubles.
Ukraine
- On average, you will have to pay 16.67 hryvnia for Metacin tablets;
- For Metacin solution in Kyiv pharmacies you will have to pay from 100 to 160 hryvnia.
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pharmachologic effect
The mechanism of action of the drug Metacin is antispasmodic. This antibiotic selectively affects M-cholinergic receptors in the periphery, relieving muscle spasms.
For this reason, the drug belongs to the pharmacological group of M-choline blockers, that is, substances that block unnecessary nerve impulses.
Metacin helps relax the smooth tissues of the muscles of internal organs:
- Removes spasms of the esophagus, intestines, stomach, gallbladder and bile ducts;
- Regulates contractile activity;
- Prevents excessive secretion of saliva, bronchial secretions and gastric juice.
Analogs
The selection of a replacement drug should be carried out by a doctor or pharmacist.
This drug has no direct analogues . However, you can choose a drug with a similar effect. These drugs include Atropine, Novitropan, Trigan, Buscopan, Driptan, Midriacin, Spazmex, Cistrin, Oxybutin, Atrovent, Gastrozem, Platyfillin, Gastrozepin, Ditropan, NO-SPA, Espumisan, Bobotik, Pepsan-R, Spasmomen, Niaspam, Meverin, Infacol, Plantex, Papaverine, Bebinos, Dicetel.
Reviews
Reviews about this drug leave only positive ones. People note that the medicine begins to act immediately, alleviating the patient’s condition.
In addition, there are a huge number of reviews from pregnant women in the communities. They note that by taking this medicine they were able to give birth to healthy children.
Nursing mothers testify that, in general, the drug did not have any effect on the child . However, there are several reports of babies having difficulty falling asleep after feeding. After stopping the medication, the child's condition stabilized.
