Pharmacodynamics and pharmacokinetics
herbal medicine . Depending on the dosage, the drug is characterized by a weak or moderate sedative effect on the human body, due to the effects of the essential oil , a significant part of which is an ester of isovaleric acid and borneol . The alkaloids of the tincture - hotenine and valerine and its compounds valepotriate - also have a calming and relaxing effect .
The sedative effectiveness of the drug develops slowly, depends on the dose and is stable. Valerian drops facilitate the process of entering natural sleep , stabilize its course and have virtually no effect on awakening.
In addition to the sedative effects, the drug exhibits a mild antispasmodic effect and a mild choleretic effect. Taking this drug has a beneficial effect on the secretory functionality of the gastrointestinal tract, dilates the vessels of the coronary system and reduces pathologically rapid heart rate. Stabilization of the activity of the heart muscle is determined by the influence of the active ingredient of the drug on the mechanisms of neuroregulation and its direct effect on the cardiac conduction system and heart automatism. Therapeutic effectiveness is formed with prolonged and systematic use.
Product effectiveness
Only the general extract of valerian has a therapeutic effect; individually its components give a very weak effect or do not have any effect at all. All forms of the drug have low biological activity, that is, the medication does not act immediately. The therapeutic effect occurs with long-term use, when the required level of the drug accumulates in the body.
Effectiveness appears after 2-3 weeks of continuous use. According to statistics, 89% of people, after using Valerian for a month, had normal sleep, irritability and emotional tension decreased. The medication is not suitable for emergency cases when you need to calm down, since a one-time dose has no effect.
Analogs
Level 4 ATC code matches:
Alora
Motherwort Extract
Novo-Passit
Cardiovalen
Liked
Carmolis
Lotusonic
Relaxil
Persen Forte
Persen
Phytosed
Sedavit
Motherwort Forte Evalar
Dormiplant
Sondox
Sedafiton
Peony tincture
Menovalen
Bromcamphor
Valerian rhizomes with roots
The most famous substitutes for this drug are herbal drip preparations, similar in their main action to Valerian Tincture: Corvalol , Motherwort , Hawthorn , Peony , Corvaldin , Valocordin , Barboval , Valecard .
Also very popular is a mixture of tinctures of valerian , motherwort , hawthorn , and peony .
You can combine these drugs yourself in equal proportions by purchasing all the tinctures separately at the pharmacy and mixing them in a larger glass bottle. You should start taking the prepared tincture of valerian, motherwort, hawthorn, peony with 10-15 drops and, if tolerated, increase the dose to a teaspoon.
Rules for use in adults
Before using the drug, you must check the expiration date. If it has expired or the medication is cloudy in color, it is better not to use it. Any expired medicine loses its healing properties.
The tincture is taken before meals, 20-30 drops, diluted with water (2-3 tablespoons), up to 4 times a day, washed down with a small amount of water. The maximum dosage of medication per day is no more than 100 drops.
The duration of treatment is up to 1 month. If prescribed by a doctor, it can be repeated after a break (1-2 weeks). The effect of the drug is weak and can be noticed only after 2-4 weeks. If you missed a dose of medication during the day, you do not need to take an additional dose the next time; skipping 2-3 doses per course will not affect the final result.
Reviews
In the post-Soviet countries, Valerian Tincture has long and consistently received only positive reviews. The only relative disadvantage for some people is the alcohol included in the drug, as a result of which pregnant and lactating women are careful not to drink it.
Also, children do not like the taste of alcohol, as well as the smell of valerian, which is why the use of this tincture in children is limited. Otherwise, valerian drops have been characterized on the positive side for a long time, are included in almost every home medicine cabinet and have no equal in popularity on the pharmaceutical market.
For what diseases is Valerian drops used?
Most often, drops are prescribed for the complex treatment of diseases of the nervous, cardiovascular, and digestive systems. Indications:
- spasm in gastrointestinal pathologies;
- disruption of enzyme production in the gastrointestinal tract;
- violation of coronary circulation;
- hypertonic disease;
- sleep disturbance;
- increased anxiety.
In most cases, the drug is prescribed precisely as a sedative, which helps to cope with the tendency to depression, hysteria, and increased excitability of the nervous system.
Read more Children's nasal drops Protargol - instructions for use, analogues
The reference book on medications states that Valerian helps reduce appetite, since it reduces the activity of the appetite center in the hypothalamus, so the drug can be used in the complex treatment of obesity. The medication also has anthelmintic and anti-inflammatory properties, but they have not been scientifically proven.
Price, where to buy
As a rule, the price of Valerian tincture does not differ much depending on the manufacturer, that is, as much as valerian drops cost from one manufacturer, it will cost the same from another. At this time, the price of 25 ml of tincture fluctuates around 10-20 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Valerian tincture fl.
25ml No. 1Kirovskaya f.f. 85 rub. order - Valerian tincture 25 mlAO Renewal of PFC
69 RUR order
- Valerian tincture 25ml JSC Moscow Pharmaceutical Factory
48 RUR order
Pharmacy Dialogue
- Valerian tincture (flask 25ml)Update PFC JSC
70 rub. order
- Valerian tincture (flask 25ml) Hippocrates
21 rub. order
- Valerian tincture (25ml bottle) Ivanovskaya farm. f-ka.
26 RUR order
- Valerian tincture bottle 25ml Tverskaya FF
21 rub. order
- Valerian tincture (flask 25ml)Flora of the Caucasus
29 RUR order
show more
Use in children
According to the instructions, the drug should not be given to patients under 12 years of age. But sometimes doctors prescribe the remedy for children over 3 years old. The dosage is calculated according to age: for 1 year – 1 drop. That is, if the child is 4 years old - then 4 drops, if 5 years old - then 5 drops up to 3 times a day, and accordingly the maximum dose per day for a 4 year old child is 12 drops, for a 5 year old child - 15.
If children are hyperactive or have sleep disturbances, you can take baths with Valerian. Add 3 drops of the product to 3-4 liters of water and bathe the baby before bedtime. Considering the side effects the drug has, it is not recommended to give the medicine to a child without a pediatrician’s prescription, especially under 3 years of age (due to the presence of alcohol in the composition).
Overdose
According to the instructions, the drug is not addictive, but to prevent an overdose, breaks are needed between courses of administration to allow the drug to be eliminated from the body. If this is not done, valerian continues to accumulate in the body, leading to poisoning. Overdose symptoms:
- dizziness;
- lightheadedness or loss of consciousness;
- drowsiness;
- depression;
- decreased concentration;
- increased fatigue, even in the absence of physical and emotional stress;
- insomnia;
- headache;
- rise in blood pressure;
- heart rhythm disturbance;
- decreased hearing and vision;
- nausea, heartburn, vomiting;
- bowel dysfunction - constipation or diarrhea.
Both alcohol and valerian roots can cause signs of poisoning. Regardless of which component caused the poisoning, the symptoms appear the same. To eliminate signs of overdose, it is enough to stop taking the drug so that its components are eliminated from the body.
To speed up the elimination process, you need to drink a lot of fluid (more than 2.5 liters) and use enterosorbents (activated carbon, Polysorb).
The lethal dose of the drug has not been determined. If you accidentally drink a bottle of Valerian (more often this applies to children), you must call an ambulance.
Possible side effects
The drug is well accepted by the body and rarely causes side effects. They usually occur in cases of overdose, when the dose at one time is not observed or the number of doses per day is exceeded, as well as when used for more than 1 month without a break.
Side effects may occur in people allergic to the components of the drug. It manifests itself as itching and rashes on the skin. In this case, antihistamines (antiallergic) are necessary. The drops may cause heartburn because they stimulate digestion by increasing the secretion of gastric juice.
Read more Rinofluimucil - how to use nasal drops for children
Contraindications Valerian drops
The tincture is contraindicated during pregnancy or breastfeeding, since during pregnancy it reaches the fetus through the blood and has a detrimental effect on its development. During lactation, the components of the drug pass into breast milk. Valerian is prohibited for children under 3 years of age. From the age of 3, taking the drug is allowed, but only with a doctor’s prescription, since even a single dose can cause symptoms of intoxication in children.
Other contraindications:
- low blood pressure;
- diseases associated with inhibition of the function of the central nervous system;
- pathologies associated with increased blood clotting ability;
- enterocolitis;
- inflammatory processes in the intestines, kidneys;
- atherosclerosis;
- taking sleeping pills, sedatives;
- alcohol intoxication.
The tincture should not be taken when driving vehicles or working in production that requires concentration (due to the presence of alcohol in the composition).
Is it possible to prepare valerian with your own hands?
Valerian tincture can be prepared at home without much difficulty. To do this, you will need 25 g of dry crushed valerian roots and 100 ml of 70% alcohol. The components are mixed and infused in a dark place for 7 days. Afterwards, the mixture is filtered through cheesecloth and poured into a glass, preferably darkened container. The resulting medicine is not inferior in effectiveness to pharmaceutical valerian, so it is taken according to the rules in the instructions.
You can prepare valerian without alcohol. To do this, pour 10 g of crushed dry roots and rhizomes of valerian into 200 ml of boiling water. Next, the infusion is heated in a water bath for 15 minutes, then allowed to cool. The mixture is filtered and poured into a glass container. Take 1-2 tablespoons up to 4 times a day.
