So, today we have to find out what the drug “Volvit” is. Instructions for its use are clear even to a child. But not everyone knows what kind of remedy this is. And even more so who should buy and use it. Let's try to understand this difficult matter. In addition, it would not hurt to find out whether Volvit, the instructions for use of which are discussed below, is really effective. Or is this just another scam calling us to spend money?
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The medicine includes biotin , which is water-soluble B vitamin the metabolism of carbohydrates, lipids and proteins and is necessary for normal cell development. Serves as an integral part of carboxylases , demonstrates an insulin-like effect and is involved in the process of gluconeogenesis , as a result of which it helps maintain blood and stimulates the functioning of the nervous system. Synergist of folic acid , other B vitamins, cyanocobalamin and pantothenic acid . There is information about the participation of biotin in the biosynthesis of purine nucleotides . The source of sulfur , necessary in the synthesis of collagen , therefore has a positive effect on the structure of the skin and its appendages.
This vitamin enters the human body mainly from food and is synthesized to a lesser extent by intestinal microflora .
Pharmacokinetics
Rapidly absorbed in the intestine due to passive diffusion. The degree of binding to blood proteins reaches 80%. Biotin crosses the blood-brain barrier and placenta. It is transformed in the body with the formation of various metabolites . It is excreted in urine and feces unchanged (approximately 50%), as well as in the form of biologically inactive metabolic products. The half-life depends on the amount of dose administered and is usually approximately 26 hours.
Side effects
Rare, associated with individual intolerance to vitamin B7. Allergic reactions are possible, manifested in the form of urticaria and other skin rashes, shortness of breath, chest pain, swelling of the laryngeal mucosa.
Contraindications
“Beauty vitamin” is contraindicated in case of individual intolerance. Children under 12 years of age are also a contraindication to taking this drug.
During pregnancy
Pregnant and nursing mothers can take Volvit only as prescribed and under the close supervision of the attending physician. There is no data on the negative effects of the drug during pregnancy or lactation.
Video: “Vitamins Volvit”
special instructions
No cases of drug overdose were identified. Excess drug is excreted in the urine within 26 hours after administration. The ability to influence reaction speed when driving a vehicle or other complex mechanisms that require concentration and reaction speed has not been identified.
Indications for use
Complex therapy in patients over 12 years of age for diseases caused by a lack of biotin:
- hair damage (excessive thinness of hair, hair loss, split ends and brittle hair, gray hair, too oily or dry hair);
- skin lesions (dry skin, oily seborrhea, dermatitis , peeling);
- nail damage (flaking, brittleness, impaired growth or structure of nails);
- biotinidase deficiency ;
- functional disorders of the digestive tract (including malabsorption );
- psycho-emotional disorders ( drowsiness , excessive irritability and fatigue, muscle weakness, apathy ).
Reviews
Reviews for this drug are different. However, summing up both negative and positive reviews and recommendations, we can note the fairly high effectiveness of this drug , provided that the rules of administration and the positive and negative interactions of the drug with other substances are followed.
The degree of effectiveness of this drug in one case or another varies. However, a positive impact, one way or another, was noted in all reviewed reviews.
It is worth noting that biotin accumulates in the body gradually , so the first effect from taking it can be expected no earlier than a week from the start of taking the drug.
Reviews about this drug can be read at the end of the section.
Instructions for use (Method and dosage)
The instructions for Volvit prescribe taking the medicine orally, before meals, with water. The recommended dosage for the treatment of hair, nails, skin lesions or nervous disorders is 5 mg of biotin daily.
When treating malabsorption syndrome, the recommended daily dose is 10 mg.
For signs of biotin in children and adults, 5–20 mg daily is prescribed.
For biotinidase in patients over 12 years of age, the recommended dose is 5–10 mg per day.
Volvit can be used long-term; one course of treatment lasts an average of 30 days.
What it is?
The body always needs vitamins to maintain health and vital functions. Unfortunately, sometimes they are not enough. And at such moments you have to buy vitamin complexes in pharmacies. “Volvit”, instructions for use, composition and analogues of which are presented to our attention, is a kind of biologically active supplement. Or vitamins that help the body cope with illnesses.
The drug is nothing more than small tablets of 5 milligrams. According to buyers, they are easy to swallow. If you regularly take Volvit vitamins, you will notice how your appearance has changed. And you yourself will become healthier. In what cases should you immediately start using the drug? After all, the product still has some recommendations, even though it is a vitamin complex.
Interaction
Valproic acid can reduce biotinidase , weakening the functions of hepatocyte mitochondria.
When using biotin with anticonvulsants, its level in the blood may decrease due to an increase in its evacuation in urine.
Pantothenic acid in high doses competes with the drug, so their simultaneous use should be avoided.
Raw egg whites contain the protein avidin , which interacts with biotin - their combined use should be avoided. Eating a large number of raw eggs for 2-3 weeks causes biotin .
Compound
To be honest, few people understand the composition of the product. Perhaps only professionals will understand it. However, it is worth exploring this point. "Volvit" contains in one tablet the main active ingredient - biotin. In addition, there are also auxiliary substances. These are dyes, magnesium stearate, sodium lauryl sulfate, croscarmellose sodium, colloidal silicon dioxide, and cellactose 80. In principle, that's all. There is nothing else in the biological supplement. So Volvit does not contain any dangerous components. You can safely take it internally.
Analogs
Level 4 ATC code matches:
Medobiotin
Calcium Pantothenate
Nicotinamide
Alpha Tocopherol Acetate
Riboflavin
Pyridoxine Hydrochloride
Pyridoxine
Vitrum Vitamin E
The most common analogues of Volvit are listed below: Deakura, Medobiotin .
Pharmacological authorities
Pharmacodynamics
.
Biotin (vitamin H, vitamin B7) is a water-soluble vitamin of group B. In the body, biotin plays an important role in the metabolism of carbohydrates, fats and proteins, and is essential for life. normal growth and development of cells. When ingested into the body, biotin serves as a coenzyme for carboxylases, performs an insulin-like action and takes part in the process of gluconeogenesis (as well as in the synthesis of glucokinase), as a result of which it combines with stabilization carcinoma in the blood, impairs the function of the nervous system. Biotin is a synergist of other group B vitamins, folic acid, pantothenic acid, cyanocobalamin. Data about the role of biotin in the synthesis of purine nucleotides. Biotin is also a sulphate that takes part in the synthesis of protein - collagen and thus positively affects the structure of the skin and its appendages (hair, nails).
Biotin deficiency can result from an unbalanced diet, unhealthy diets and the consumption of raw egg whites; with parenteral food; with malabsorption syndrome, after resection of the small intestine; in association with biotin there is multiple deficiency of carboxylases; in patients who are on hemodialysis.
Pharmacokinetics.
In the body, biotin is rapidly absorbed from the small intestine through passive diffusion, after which it is absorbed through the portal system into the liver and further into the systemic bloodstream. The level of biotin binding to blood plasma proteins becomes 80%. The concentration of free or weakly bound biotin in the blood usually becomes 200 to 1200 mcg/l. Biotin passes through the hematoencephalic and placental barriers. Metabolized in the body through the release of various metabolites. Biotin is excreted from the body (from 6 to 50 mcg per dose) and feces in unchanged form (about 50%), as well as in the form of biologically inert metabolic products. The dosage period remains consistent with the dose administered and becomes approximately 26 years after the administration of an internal dose of 100 mcg per kg of body weight. In patients with biotinidase deficiency, the recovery period after administration of the same dose is shortened to 10-14 years.
Volvita price, where to buy
The cost of the drug with a dosage of 5 mg No. 30 in Ukraine is on average 105 hryvnia. The price of Volvita in Russia in the same release form can reach 680 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
LuxPharma* special offer
- Volvit tab.
5 mg N30 RUR 1,750 order
show more
Pharmacy24
- Volvit 5 mg No. 30 tablets Kusum Healthker PVT.LTD, India
121 UAH order
PaniPharmacy
- Volvit film-coated tablets 5 mg No. 30 India, Kusum Healthcare
132 UAH order
show more
Summarizing
So we found out what Volvit is. Instructions for use, analogues, composition are now known to you. As you can see, this drug, which is made in India, is not worth spending money on. This, as already mentioned, is more of a dietary supplement than some kind of medical product. And you most likely will not achieve results after use.
In order to improve the condition of the skin, as well as nails and hair, it is best to consult with your doctor. He will prescribe you medications and regular vitamins. They will definitely give results. And they won’t hit your pocket very hard. However, whether it is worth buying Volvit or not is a purely individual decision.
Volvit reviews from doctors and patients
Doctors speak positively about the drug, noting its high effectiveness in the treatment of all diseases indicated in the indications for use. Side effects are observed extremely rarely, are expressed mainly by skin rash, and go away without additional treatment after discontinuation of the drug.
Feedback from patients is also positive - after a course of the drug, the majority show significant improvement. Hair begins to grow stronger, becomes strong and silky, and stops falling out and splitting. The strength of the nails returns and they stop peeling. Very rarely, symptoms reappeared after discontinuation of the drug.
04/22/2018 PreparationsComments: 0 “Vitamins Medobiotin - instructions for useBiotin for hair”
Features of good stagnation
Do not ruin the triviality of the course of treatment prescribed by the doctor. In cases of intermittent or frequent treatment, the effect of the drug may change. Due to the good tolerance of biotin, the bath can last up to an hour.
Influence on the results of clinical laboratory investigations.
Biotin can be used to influence the results of clinical laboratory studies, which are based on the biotin/streptavidin interaction, which can lead to a slight decrease or increase in data, depending on the type of study. The risk of this is greater in children and patients with impaired function, and also increases with higher doses of biotin. When interpreting the results of the follow-up, be aware of the possible influx of stagnant biotin in the patient, especially if such data are not suitable for an obvious clinical picture (for example, clinically positive results of the follow-up Women's function of the thyroid gland during Graves' disease or negative results of troponin level analysis in patients with myocardial infarction). When planning clinical laboratory investigations in patients taking biotin, please consult with appropriate laboratory specialists in advance. In these cases, if the possibility of injecting biotin on the results of the investigation is not turned off, it is necessary to use alternative tests so as not to lie with this official.
Additional speeches.
The drug contains Ponceau 4R (E 124), which may cause allergic reactions.
Interactions with other medicinal drugs and other types of interactions
When biotin is taken with anti-drug drugs, there may be a decrease in the concentration of biotin in blood plasma due to increased excretion of biotin from the body. Valproic acid reduces the activity of biotinidase, reducing the functions of mitochondria in the liver.
Raw egg whites are mixed with avidin protein, which interacts with biotin, thus preventing their immediate absorption. Living with large quantities of raw eggs for 2-3 days can cause biotin deficiency.
In high doses, pantothenic acid competes with biotin, which is why they are unique to one-hour stagnation.
