Antiseptic agent Valenta Pharmaceuticals Grammidin with anesthetic NEO (Grammidin with anesthetic NEO) - reviews

Cough medicine grammidin

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Grammidin

is an antibacterial drug intended for topical use for various infectious and inflammatory diseases of the oral cavity and pharynx (pharyngitis, tonsillitis, tonsillitis, periodontitis, gingivitis, stomatitis).

Varieties, names, release forms and composition

Currently, Grammidin is available in the following varieties:

• Grammidin;
• Grammidin for children;
• Grammidin Neo;
• Grammidin with anesthetic;
• Grammidin with anesthetic Neo.

Thus, there are five types of the drug, which differ from each other in the presence or absence of additional active components or their dosages and, accordingly, some features of the therapeutic effects. All five varieties of Grammidin contain the same main active substance, but in different dosages.

But Grammidin varieties also contain other, additional active components that do not change the main therapeutic effect, but only give it some additional nuances or features.

In principle, since all varieties of Grammidin have the same basic effect, they can be considered together, indicating only the characteristic features of each type of drug.

Varieties of Grammidin are commonly called by official names (for example, Grammidin Neo, Grammidin with anesthetic, etc.). The only varieties of the drug that have a different common name from the official one are Grammidin with anesthetic and Grammidin with anesthetic Neo.

These varieties are commonly called “Grammidin red”

, since the packaging of these tablets shows a red scarf. The packaging of other varieties of Grammidin also features a scarf painted in different colors.

Moreover, each type of drug corresponds to a scarf of a certain color shown on the packaging.

All varieties of Grammidin are available in the same single dosage form - lozenges

.

All varieties of Grammidin include gramicidin C

in the following different dosages:

• Grammidin – contains 1.5 mg (1500 units) of gramicidin C per tablet;
• Grammidin for children - contains 1.5 mg (1500 units) of gramicidin C per tablet;
• Grammidin Neo – contains 3 mg (3000 units) of gramicidin C per tablet;
• Grammidin with anesthetic - contains 1.5 mg (1500 units) of gramicidin C per tablet;
• Grammidin with anesthetic Neo - contains 3 mg (3000 units) of gramicidin C per tablet.

Thus, Grammidin, Grammidin for children and Grammidin with anesthetic contain 1.5 mg of the main active substance, and Grammidin Neo and Grammidin with anesthetic Neo - 3 mg each.

Additional active ingredients contain the varieties Grammidin for children, Grammidin Neo, Grammidin with anesthetic and Grammidin with anesthetic Neo.

Moreover, Grammidin for children, Grammidin Neo and Grammidin with anesthetic contain one additional active component, and Grammidin with anesthetic Neo - two.

The composition and dosage of the main and additional active components of all varieties of Grammidin are shown in the table:

The main active component of the drug, gramicidin C, has an antibacterial effect, destroying various bacteria that can cause infectious and inflammatory diseases of the oral cavity and pharynx.

Additional active ingredient cetylpyridinium chloride

expands the spectrum of antimicrobial action of the drug, since it has a detrimental effect on viruses, fungi and protozoa. And gramicidin, in turn, destroys bacteria.

Lidocaine hydrochloride

and
oxybuprocaine hydrochloride
, being additional active components of Grammidin with anesthetic and Grammidin with anesthetic Neo, have an analgesic effect, relieving pain in infectious and inflammatory diseases of the oral cavity and pharynx.

Varieties of Grammidin include various excipients shown in the table below:

*

flavoring may be missing

Grammidin and Grammidin with anesthetic are available in the form of round tablets, colored white or white with a yellowish tint and packaged in 10 or 20 pieces.

Grammidin for children is available in the form of round, biconvex tablets, equipped with a chamfer (beveled edge) and GR engraving on one side. The tablets have a raspberry odor and are white or white with a yellowish tint. Packed in cardboard boxes of 12, 18 and 24 pieces.

Grammidin Neo and Grammidin with anesthetic Neo are available in the form of round biconvex tablets, colored white and engraved with GR on one side. Packed in cardboard boxes of 12, 18 and 24 pieces.

Therapeutic effect

If a child under 12 years of age is sick

, then it is optimal to use Grammidin for children or regular Grammidin without additional active ingredients. Moreover, children's Grammidin is best used if an infectious-inflammatory disease of the oral cavity and pharynx is suspected of a viral nature, and regular Grammidin is best used for bacterial infections.

Teenagers over 12 years old and adults

it is necessary to select Grammidin among the “adult varieties”, such as Grammidin, Grammidin with anesthetic, Grammidin Neo and Grammidin with anesthetic Neo.

So, if a teenager over 12 years of age or an adult presumably has a bacterial infectious-inflammatory disease of the oral cavity or pharynx (this can be easily understood by the presence of pus in the discharge), then he should choose Grammidin or Grammidin with an anesthetic.

Simply, Grammidin is suitable for not too intense pain in the throat and oral cavity, and Grammidin with an anesthetic should be preferred for severe pain.

In principle, you can combine the use of Grammidin and Grammidin with an anesthetic, for example, using Grammidin in the daytime, and in the evening, before bedtime, Grammidin with an anesthetic, to ensure quick falling asleep and more or less comfortable sleep.

Source: https://ckiom.ru/kashel/lekarstvo-ot-kashlya-grammidin/

Causes and symptoms of chronic sore throat in adults

The immediate cause of sore throat is bacteria and, much less frequently, viruses that settle in the tonsils. The most common causative agent of inflammation of the tonsils is β-hemolytic streptococcus. But tonsillitis is also caused by streptococci of other species, staphylococci, Haemophilus influenzae, Proteus and other microorganisms. As a rule, these are representatives of opportunistic flora, which exhibit their pathogenic properties when immunity decreases.

Local immunodeficiency, that is, a local decrease in immunity, is most often associated with an acute respiratory viral infection. Therefore, prevention of chronic sore throat is protection against colds and timely intake of the right drug.

“Is sore throat contagious?” - many patients are interested. This is an infectious disease, so a healthy person can become infected from a sick person. Microorganisms are transmitted by airborne droplets. How many days is sore throat contagious? Usually the dangerous period lasts 5-7 days, when the temperature persists. But until complete recovery, it is better to follow standard precautions to avoid becoming infected - use personal utensils, wash your hands well, do not come close to a sick person, and especially not kiss.

Angina in adults occurs in waves. Periods of remission are followed by exacerbation, when the main symptoms appear - a sore throat that gets worse when swallowing, and a low-grade fever. In addition, there may be other manifestations - discomfort in the throat; bad breath; purulent plaque on the tonsils; enlargement of the submandibular and cervical lymph nodes; joint pain and pain in the heart area.

How many days does a sore throat last? Acute inflammation of the tonsils usually lasts for 7-10 days. If a person begins treatment late, the acute process becomes chronic. How long does a sore throat last in this case? Chronic tonsillitis can remain with a person for life. The disease periodically worsens when microorganisms become active.

Grammidin Neo is an indispensable assistant in your home medicine cabinet!

The drug Grammidin Neo is an antiseptic used for topical use for the treatment of ENT diseases, incl. acute infections.

The drug is combined in composition, including components of anti-inflammatory and antibacterial action.

The product helps to soften the throat and perform mechanical cleansing at the very source of inflammation. The antibacterial effect helps slow down the growth and reproduction of pathogenic microorganisms and blocks the expansion of their location.

The drug must be taken strictly according to the instructions. Its effect becomes noticeable after a third of an hour and continues for 4 hours or more.

Features of pharmacodynamics include the absence of absorption of the drug by the gastrointestinal tract, ensuring the almost complete absence of manifested systemic effects.

Indications for use

Grammidin Neo is prescribed for the treatment of diseases caused by pathogenic bacteria that are sensitive to its individual components, including:

• angina;
• tonsillitis;
• pharyngitis.

The drug has an effect on all of the listed diseases, occurring in both acute and chronic forms.

In addition to ENT diseases, the drug can be prescribed for the treatment of oral cavity pathologies, such as:

• periodontal disease;
• gingivitis;
• stomatitis.

Despite the fact that Grammidin Neo is available freely in pharmacies without a prescription, its use should be monitored by a specialist who can assess the effectiveness of action and the appropriateness of use in each specific case.

Lack of control when using antibacterial agents can cause the emergence of pathogens that are resistant to the action of traditional medications.

Release form, composition

The composition of the drug Grammidin Neo includes the following active ingredients:

• gramicidin hydrochloride – 3 mg;
• cetylpyridinium chloride – 1 mg.

In addition, there are excipients:

• acesulfame potassium;
• sorbitol;
• talc;
• silicon dioxide;
• magnesium stearate;
• mint flavor.

The compound gramicidin hydrochloride is an antimicrobial component, its action is aimed at a sharp increase in the permeability of cell membranes in pathogenic pathogens, leading to significant changes in the metabolic processes of bacteria, leading to their death.

Its effectiveness has been confirmed against a significant number of different microorganisms, including both gram-positive and gram-negative. In addition, it has little effect on infections of fungal origin.

Cetylpyridinium chloride has an antiseptic and pronounced anti-inflammatory effect. The presence of this compound in the drug Grammidin Neo ensures its ability to suppress unpleasant symptoms that occur during infectious diseases of the throat, such as painful swallowing reflex, inflammation, soreness, irritation.

The drug also affects the processes of salivation, the increase of which stimulates the natural cleansing of the oral cavity.

Mint flavoring, present as an auxiliary component, gives the medicine a pleasant, refreshing, minty taste that occurs when absorbed.

Grammidin Neo is produced in the form of large-diameter, round-shaped, white tablets. Usually on one side there is an engraving of the abbreviation GR.

The package usually contains six tablets.

The drug is dispensed at the pharmacy without a doctor's prescription.

Interaction with other drugs

This drug exhibits the ability to enhance the effect achieved when using other local and systemic agents aimed at combating various pathogens.

Side effects

Taking Grammidin Neo in the most exceptional cases may be accompanied by side effects, which is due to its low coefficient of systemic action.

Sometimes you can notice the manifestation of allergic reactions on the skin, such as a rash similar to hives, swelling.

As a rule, such symptoms disappear on their own with the end of the therapeutic course.

Otherwise, if other adverse reactions occur, you should consult a doctor to prescribe the necessary symptomatic treatment.

Contraindications

Grammidin Neo is a drug that has virtually no restrictions on its use. Its use is contraindicated:

• children under four years of age;
• pregnant women during the first trimester;
• with existing hypersensitivity to its constituent components.

During pregnancy

This drug is not recommended for use during the first trimester of pregnancy. It should also not be taken while breastfeeding.

Storage conditions and periods

The drug should be stored in a dry place, out of reach of children. The air temperature should not exceed 25 degrees.

The shelf life is two years.

Price

buy Grammidin Neo in Russian pharmacies for an average price of 170 to 200 rubles.

The cost of the drug Grammidin Noe in Ukraine varies from 270 to 350 UAH.

Sore throat in adults: we treat not only the symptoms

According to statistics, about 30% of the population of Earth 1 suffer from chronic inflammation of the tonsils. Usually the reason lies in the person himself, who does not pay due attention to the acute symptoms of a sore throat, believing that they can go away on their own. However, this does not always happen. The disease, which is dangerous precisely because of its complications, very often becomes chronic. In total, about 100 diseases are known 2, the mechanisms of which are in one way or another connected with chronic inflammation of the tonsils. How to protect the body? What medications should you take and what pills should you keep in your medicine cabinet?

Why is chronic tonsillitis dangerous?

Now doctors all over the world are unanimous that chronic tonsillitis is a general, and not a local, infectious process in the body. Lesions affect almost all organs and systems, but have varying degrees of severity. The primary focus is localized in the palatine tonsils, so by acting on it in time, you can prevent the development of serious diseases.

Complications of chronic tonsillitis are the result of various pathogenetic links. This:

• Toxic effects. The toxins released by bacteria travel through the blood and lymph to various organs, grossly interfering with their functional activity.
• An imbalance of the immune system, which causes increased sensitivity of the body (sensitization) to staphylococcal and streptococcal antigens.
• Neuro-reflex disorders. Pathological nerve impulses from the tonsils reach the subcortical centers of the brain, causing disturbances in the autonomic innervation of internal organs. However, gramicidin c has a number of important advantages over many other antibiotics. let's look at them in more detail.

Indications

The tablet form is prescribed for diagnosing infectious and inflammatory lesions of the throat and oral cavity:

• gingivitis;
• stomatitis;
• acute pharyngitis;
• angina;
• periodontal disease;
• tonsillitis.

The drug in the form of a paste is usually used in the treatment of wounds and burns, since the drug “Grammidin” acts as a local antibacterial agent. Alcohol, water and fat solutions are also prescribed for burns, ulcers, purulent wounds, bedsores, and furunculosis. The product is used to irrigate tampons and bandages, and when washing wounds. The drug "Grammidin" with an anesthetic contains a special substance - oxybuprocaine, which provides an antiseptic and local anesthetic effect, which is also supported by the action of lidocaine. This medication is successfully used to treat diseases of the oral cavity.

If the patient adheres to a comprehensive treatment plan, the drug can be used in the treatment of infected eczema of the eyelids, barley, otitis externa, scleritis, blepharitis, and iritis.

Answers on questions

1. What is better – Grammidin spray or tablets?
   

   Spray and tablets have the same composition. The first form is preferable for treating hard-to-reach areas three times a day. Tablets – up to 4 times a day.

2. Which is better Grammidin - red or green?
   

   The packaging of the Grammidin line is clearly designed: with a green scarf, it contains an antiseptic and antibiotic, used for moderate sore throat. With a red scarf, it contains an anesthetic. This form is used for severe sore throat, as it blocks sensitive nerve endings. Red Grammidin is stronger and more expensive. What to choose depends on the intensity of the pain syndrome.

3. Can Grammidin be used by pregnant women or not?
   

   Grammidin is not used during pregnancy and breastfeeding. If pain occurs in patients from this group, you should consult a doctor and choose safe analogues (rinsing with soda, sea salt or water, furatsilin, sucking Lizobact tablets).

Mode of action of the drug

In each of the described drugs in the series, the active ingredient is gramicidin C (hydrochloride). To the question whether grammidin is an antibiotic or not, the answer is yes.

Gramicidin is a broad-spectrum antibacterial drug; it is active against almost all pathogenic coccal microorganisms (gram-positive and gram-negative) living in the oral cavity and nasopharynx. When applied topically, the drug quickly penetrates microbial cells and disrupts the integrity of their walls, as a result of which the bacteria die.

Most lozenges (except for the children's form) additionally contain an antiseptic (cetylpyridinium), an anesthetic (lidocaine), and essential oils (eucalyptus), which also have a detrimental effect on pathogenic microflora. To relieve pain, lidocaine, peppermint oil, menthol are used, and for additional effects on microorganisms, cetylpyridinium (its effect is enhanced by an antibiotic)

The spray also contains essential oils that relieve pain and burning, and an antiseptic.

Contraindications

It is prohibited to use Grammidin for sore throat in the following cases:

1. during the first three months of pregnancy;
2. when breastfeeding your baby;
3. the child is under 12 years of age;
4. allergic reaction to the main and auxiliary components of the drug;
5. intolerance to lactose, sucrose;
6. diabetes mellitus

Medical opinion

Next, you should indicate what kind of reviews among practicing doctors the drug “Grammidin” with an anesthetic was able to generate:

• Many doctors buy this drug for their home medicine cabinet. This is an excellent antiseptic for the throat and mouth, suitable for treating all family members. The cost of the product is slightly higher than that of analogues, but it is worth it. If you use the drug strictly according to the instructions, you can quickly feel the expected effect. The tablets must be dissolved thoroughly. An antiseptic will help alleviate the condition of sore throat, pharyngitis, and infectious diseases of the gums. The drug has a pleasant mild taste.
• The drug "Grammidin for children", reviews of which are heard more and more often, is one of the few medications prescribed for the treatment of children. Its balanced, safe composition helps to quickly eliminate throat diseases in children starting from the age of four. The product has a pleasant taste, and therefore children take these lollipops with pleasure.
• Many practicing dentists prescribe this drug to their patients to treat oral diseases. It effectively relieves the acute phase of inflammation, helps heal ulcers and wounds. Complex therapy becomes much more effective.
• Grammidin neo tablets are the only remedy that can be purchased at a pharmacy without fear without providing a prescription form. It is truly safe if the intake is completely consistent with the recommendations given in the instructions.