Description and composition
The dietary supplement Neurovitan contains the following active ingredients:
- octothiamine;
- riboflavin;
- pyridoxine hydrochlorine;
- Cyanocobolamine.
The composition also contains auxiliary elements:
- gelatinized starch;
- microcrystalline cellulose;
- colloidal silicon dioxide;
- purified talc;
- Burr oil;
- red and yellow dye;
- gelatin;
- Magnesium stearate.
The listed auxiliary components provide the required dosage form.
Pharmacological group
According to its pharmacological group, the drug Neurovitan can be considered as a vitamin preparation or dietary supplement. The product has the following effects:
The vitamins present in Neurovitan belong to the group of water-soluble vitamins. The effect of the drug is due to the effects of its constituent compounds.
Component B2 actively influences neuromuscular regulation, influences the conduction of nervous excitation in cholinergic synapses, and is necessary for the production of the neurotransmitter acetylcholine. Component B6 is required for the normal functioning of the central and peripheral nervous systems. The substance takes part in carbohydrate, lipid and protein metabolism, participates in the synthesis of neurotransmitters (dopamine, norepinephrine, adrenaline, histamine).
Cyanocobalamin has a beneficial effect on the functions of the nervous system and liver, is a growth factor and a stimulator of hematopoiesis. The substance activates blood clotting processes, carbohydrate and lipid metabolism. Vitamin PP provides regulation of carbohydrate metabolism.
Neurovitan: vitamins specifically for nerves
Our life is solving problems at work, meetings, calls from clients and communication with colleagues, traffic jams, queues and searching for goods in stores, helping family members, household chores and millions of other things... And all this is certainly associated with overload, anxiety and excitement , grievances and sorrows. And stress. |
Stress is a part of our existence. He enters everyone's life with the morning alarm. Day after day, the doors of the subway, buses and trolleybuses open in front of us to sow the next portion of irritation. Finding ourselves on the road behind the wheel of a car, we constantly get stuck in traffic jams and cannot forget about the risk of an accident. Car horns, someone's imbalance, aggressiveness, and bad mood unceremoniously invade the well-being and sense of self of many of us and often affect relationships with colleagues and family members. Television programs, newspapers and magazines also make it difficult to get into a calm mood, bombarding us with frightening messages about economic crises, natural disasters and environmental disasters. Even when going to sleep, experiences, often unpleasant, painful and devastating, torment the memory and weigh heavily on the soul. Where can you find the strength to launch your boat again and again towards the raging sea of life? What can serve as support and help restore performance, improve endurance, and strengthen the immune system?
Stress is the body’s response to extreme conditions that disrupt a person’s emotional calm and balance. You are probably familiar with the expression “all diseases come from nerves”? After all, it is the nervous system that is the first to receive all the negative information entering the body from the environment. Its excessive amount, which causes disturbances in the emotional sphere, can cause a malfunction of the nervous system, which ensures the vital functions of the entire human body. The most important functions of the nervous system are to receive, store and process information, the source of which is the external and internal worlds, that is, the environment and the organism itself. If the nervous system quickly and accurately performs its functions, then all other organs and systems of the body work harmoniously and clearly. This is the key to long life and good health. But if the functions of the nervous system are impaired, then the entire body cannot work normally: diseases arise, the cause of which is extremely difficult to find, because it lies in the unbalanced functioning of the nervous system.
Our story could have ended on this sad note if there had not been a remedy that strengthens and nourishes the nervous system, allowing it to work harmoniously and clearly. We are talking about the drug NEUROVITAN® - a modern complex of B vitamins, presented in Ukraine.
The composition of the drug Neurovitan® includes:
vitamin B1 (octothiamine) 25 mg
vitamin B2 (riboflavin) 2.5 mg
vitamin B6 (pyridoxine hydrochloride) 40 mg
vitamin B12 (cyanocobalamin) 250 mcg
Octothiamine (a derivative of vitamin B1 and a-lipoic acid) takes an active part in the metabolism of carbohydrates and fats and is necessary for the synthesis of nucleic acids. Potentiates the effect of acetylcholine, which is involved in the transmission of nerve impulses. Strengthens tissue respiration, improves oxygen supply to skin cells. Riboflavin (vitamin B2) is involved in tissue respiration and ATP synthesis, the synthesis of higher fatty acids and other processes of energy supply to the cell. Performs antioxidant functions, helps increase the level of hemoglobin and red blood cells. Improves eye function, promoting improved color perception and dark adaptation. Pyridoxine (vitamin B6) is necessary for the metabolism of amino acids, fats and carbohydrates, as well as for the synthesis of serotonin and histamine. Participates in the breakdown of cholesterol, synthesis and nutrition of the myelin sheath of the peripheral nerve and axon. Vitamin B6 deficiency leads to the development of neuromuscular dystrophy and seizures. Cyanocobalamin (vitamin B12) is involved in protein, fat and carbohydrate metabolism. Helps reduce cholesterol levels in the blood and remove it from the body. By stimulating protein synthesis, it normalizes the processes of growth and development. Regulates hematopoietic processes. By increasing the phagocytic activity of leukocytes and activating the activity of the reticuloendothelial system, it enhances the body’s immunological defense.
Octothiamine is a fat-soluble compound with higher bioavailability and prolonged action compared to water-soluble thiamine salts (bromide, nitrate, chloride). It is well absorbed in the intestine, penetrating through lipophilic cell membranes in proportion to the dose taken, and reaches high intracellular concentrations in all tissues of the human body (especially in the cells of the nervous tissue). Particular attention should be paid to the presence of vitamin B2 in NEUROVITAN® , which is absent in many other vitamin complexes. The fact is that the processes of metabolism and physiological (pharmacotherapeutic) action of B vitamins are interconnected, and vitamin B2, for example, is necessary for the conversion of pyridoxine and pyridoxamine phosphates (vitamin B6) into coenzyme pyridoxal 5-phosphate (McCormick DB, 1989). The developers of the drug NEUROVITAN® made sure that its components do not interact with each other, thereby eliminating reactions that are undesirable for the patient’s body.
In terms of therapeutic effectiveness, NEUROVITAN® is not only not inferior to injection forms of B vitamins, but surpasses them in the speed of onset of clinical effect (Fadeenko G.D. et al., 2001; Voloshina N.P. et al., 2003; Kravchun N.A. et al., 2004; Kutasevich Ya.F. et al., 2005).
Thus, NEUROVITAN® is an effective complex of B vitamins in high doses and a-lipoic acid for enteral use, which has advantages over traditional parenteral administration of these substances, is well tolerated, has a wide range of indications for use, and is especially recommended for inclusion in therapeutic regimens. activities in neurological patients (Voloshina N.P. et al., 2003; Treatment of diabetic polyneuropathy and other dystrophic-degenerative and inflammatory diseases of the peripheral nervous system with metabolic drugs. Methodological recommendations, 2004). Thanks to the rational combination of composition , which complement each other, a more pronounced therapeutic effect is noted. Long-term use of NEUROVITAN leads to normalization of nervous and muscle disorders, elimination of deficiency of B vitamins (Kravchun N.A. et al., 2004; Volosovets A.P. et al., 2005). By taking NEUROVITAN® 1 tablet per day for 30 days, your patients will be able to easily cope with stress and get rid of anxiety and depression. Thanks to the drug, you can overcome fatigue and irritability, help improve memory and mental performance. NEUROVITAN® is an effective protection against the effects of stress. NEUROVITAN® are vitamins specifically for nerves.
Noteworthy is the fact that, according to the analytical market research system "Pharmstandard", the sales volume of the drug NEUROVITAN® in the pharmacy chain of Ukraine in the first half of 2006 compared to the first half of 2005 increased by 74 and 78% in natural terms and in monetary terms, respectively. This rate of sales growth indicates a competent marketing policy and the demand for the drug among the general population of our country. o
LITERATURE |
1. Volosovets A.P., Krivopustov S.P., Dzyuba O.L., Loginova I.O., Grichina L.M. Application of Neurovitan in complex rehabilitation of perinatal lesions of the central nervous system. Modern pediatrics. - 2005. - No. 2. 2. Voloshina N.P., Grigorova I.A., Bogdanova I.V. Use of the drug Neurovitan in modern treatment regimens for neurological diseases. Guidelines. - Kharkov, 2003. 3. Kravchun N.A., Zemlyanitsina O.V., Kozakov A.V. Use of the drug Neurovitan for the treatment of polyneuropathies in endocrine diseases. Guidelines. - Kyiv - Kharkov, 2004. 4. Kutasevich Ya.F., Oleinik I.A., Mashtakova I.A. Vitamin therapy using the complex drug Neurovitan in dermatological practice. Guidelines. - Kyiv - Kharkov, 2005. 5. Treatment of diabetic polyneuropathy and other dystrophic-degenerative and inflammatory diseases of the peripheral nervous system with metabolic drugs. Guidelines. - Moscow, 2004. 6. Fadeenko G.D. Neurovitan in the complex treatment of patients with intestinal dysbiosis. Ukrainian medical journal. - 2001. - No. 5. 7. McCormick DB Two interconnected B vitamins: riboflavin and pyridoxine. Physiol. Revs., 1989. 69: 1170–98. |
Press service of “APTEKA Weekly”
Indications for use
It is recommended to prescribe a dietary supplement to the daily diet to patients with an increased risk of hypovitaminosis B. The drug can also be prescribed to patients with asthenic pathologies.
for adults
Patients in this age group can use medication if indications for use are identified. In general, the composition is well tolerated, adverse reactions are extremely rare. The product should be used with particular caution by people suffering from allergic reactions due to the high risk of an immune response.
for children
The vitamin supplement Neurovitan can be used in pediatric practice. The product is recommended for use in patients over 1 year of age. The product should be used in doses prescribed by your doctor. An overdose of vitamins is dangerous for young children.
for pregnant women and during lactation
the period of pregnancy and breastfeeding is considered a contraindication to the use of the drug. Taking the composition may cause negative reactions. In rare cases, doctors allow taking vitamin B in severe asthenic conditions in a pregnant woman. The progress of gestation in this case should be monitored.
Side effects
In general, the drug is well tolerated and provides a pronounced therapeutic effect. Especially with long-term use.
Please note that vitamin B2 can color urine yellow. This condition is normal.
Side effects to the components of the drug occur very rarely.
The following manifestations were noted:
- weakness, increased sweating, slight rise in body temperature;
- increase or decrease in blood pressure, feeling of heat;
- tachycardia;
- allergic manifestations;
- stomach pain, indigestion, flatulence, dry mouth;
- itching in the eyes.
Contraindications
The main contraindication to taking Neurovitan is individual intolerance to one or more components of the drug. Usually manifests itself in the form of an allergic rash.
But other manifestations may also occur. Allergies can occur to both vitamins and excipients. In this case, you should stop taking it and discuss with your doctor the need to select another medicine.
Neurovitan contains lactose. Patients with lactose intolerance should refrain from taking the drug.
You cannot combine taking Neurovitan with drinking alcoholic beverages. Alcohol inhibits the effect of vitamins.
You should not take the drug for acute heart diseases accompanied by cardiac arrhythmias.
It should be borne in mind that vitamin B6 in large quantities reduces breast milk production . When prescribing the drug during lactation, you should discuss with your doctor the possible consequences and dosage.
Neurovitan is not used for children under 3 years of age.
If there is thickening of the blood or blood diseases with a risk of blood clots, you should consult your doctor before taking the drug.
During an exacerbation of peptic ulcer disease, you should refrain from taking Neurovitan.
During pregnancy
The drug is prescribed during pregnancy to prevent or treat vitamin deficiencies in the body. But the need to take Neurovitan is assessed by the attending physician in each specific case.
Applications and dosages
The dosage regimen for a vitamin supplement is determined individually for each patient depending on the patient’s age, weight, and indications for use. In order to compensate for the deficiency of vitamin B with a slight decrease, the composition is used in a dose of 1 tablet per day.
for adults
Patients in this age category can use the drug when indications for use are identified. The composition is often prescribed for colds in elderly people to increase the effectiveness of the therapeutic effect. The composition is generally well tolerated; adverse reactions associated with its use are quite rare.
for children
Neurovitan can be used in pediatric practice when indications for use are identified in a patient. In general, the drug is well tolerated, hypersensitivity reactions are rare. Children use the product at a dose of 0.5-1 tablet per day. After taking the product, you should drink it with a sufficient amount of water. Do not bite or crush the tablet.
for pregnant women and during lactation
There are no data that can accurately establish the safety of using the medicinal composition. The drug can provoke adverse reactions in women and cause the development of pathologies in the fetus. The possibility of taking medication should be discussed with your doctor individually.
Instructions for use
Neurotropic drugs also improve intercellular connections in the brain. As a result, memory and intelligence improve, and concentration increases.
Another positive property is the normalization of the hormonal system due to improved functioning of the hypothalamus . The processes of processing proteins, fats and carbohydrates into energy are normalized.
The B vitamins have a beneficial effect on the nervous system .
Indications for use of the drug
Neurovitan is useful for an active lifestyle. It helps the nervous system cope with stress and the effects of negative factors (unbalanced diet, sleep disorders, bad habits).
It is also indicated for general weakening of the body (surgeries, illnesses, taking potent drugs, pregnancy, etc.).
Neurovitan is prescribed for the following conditions:
- Loss of strength (chronic fatigue syndrome);
- disorders and diseases of the nervous system;
- liver diseases;
- pregnancy;
- deficiency or excess of vitamins during lactation or pregnancy;
- endocrine disorders;
- period of increased brain load;
- stressful conditions;
- diseases of the heart and blood vessels;
- autoimmune processes in the body;
- skin diseases;
- deterioration of hair condition;
- gynecological diseases;
- weakened immune system;
- alcohol or smoking abuse, poor nutrition, physical activity, irregular sleep;
- diseases of the spine;
- Iron-deficiency anemia;
- with increased physical activity;
- paralysis or inflammation of the facial nerve;
- in case of disorders of the digestive system;
- for eye diseases.
For any conditions that are accompanied by poor health, taking Neurovitan will be useful. Except for the cases described in the “Contraindications” section.
Video: “Overview of the appearance of the drug Neurovitan”
Mode of application
Patient age | Daily dose |
Children from 3 to 7 years old | 1 tablet |
From 8 to 14 years | 1-3 tablets |
Children over 14 years old and adults | 4 tablets |
For pregnant | 1 tablet |
During lactation | 2 tablets |
The doctor selects the required dosage. One course of treatment lasts from 14 to 28 days. |
Release form, composition
The composition of the drug includes:
- Octothiamine (a compound of vitamin B1 and lipoic acid) - 25 mg. It is a component of enzyme systems. Actively participates in the breakdown of carbohydrates and fats. Necessary for the production of nucleic acids. Strengthens the transmission of nerve impulses. Affects the functions of the muscular and autonomic nervous system. Normalizes gas exchange in tissues (saturates with oxygen). Especially
It is important to take vitamin B1 in case of toxic poisoning of the body and in stressful situations. In combination with acid, the beneficial functions of the vitamin are enhanced. Contraindicated for allergies. - Vitamin B2 (riboflavin) - 2.5 mg. Also involved in the enzyme system. Regulates metabolic processes. Responsible for cell reproduction, regeneration and growth. Important for proper eye function, protects the retina from the harmful effects of ultraviolet rays. Also normalizes intestinal function. Participates in wound healing and skin restoration.
- Vitamin B6 (pyridoxine hydrochloride) - 40 mg. Participates in metabolic processes. Normalizes the processes of the cardiovascular system, hematopoietic organs, and nervous system. Improves the condition of skin and hair. Do not take for peptic ulcers during exacerbation.
- Vitamin B12 (cyanocobolamine) - 0.25 mg. Responsible for hematopoiesis. Enhances blood clotting. Normalizes the functioning of the liver and digestive organs. Supports the functioning of the nervous system. With a lack of vitamin, there is a clear decrease in performance, weakness and loss of strength. Contraindicated in certain blood diseases associated with the risk of blood clots.
As auxiliary components, Neurovitan contains: starch, cellulose, colloidal silicon dioxide, magnesium, talc, gelatin, titanium, sucrose, paraffin, povidone, ricin oil, shellac, red and yellow dyes.
The unique composition of Neurovitan and correctly selected doses of vitamins in it also affect the effectiveness of treatment.
It has been clinically proven that this complex achieves a greater therapeutic effect compared to taking the same vitamins separately.
In addition, the constituent substances of Neurovitan are in separate microcapsules for better absorption.
Most absorption occurs in the small intestine. For distribution to tissues, the components bind to blood plasma proteins. They are eliminated from the body by the urinary system.
The drug is available only in the form of tablets, 10 pieces in a blister. Three records per pack.
Video: “Description of the drug Neurovitan”
Interaction with other drugs
With the simultaneous use of Neurovitan with Levodopa, the antiprakinsonian effect of the latter is significantly reduced (due to vitamin B6).
It is not recommended to take Neurovitan with any other vitamin complexes to avoid overdose.
Some diuretics (furosemide and the like), when taken for a long time, reduce the absorption of vitamin B1.
When taken simultaneously with oral contraceptives, the body's need for pyridoxine increases.
Analogs
As analogues, you can consider other products containing B vitamins.
Neuromultivitis
The product contains B vitamins. Neuromultivit is produced in the form of tablets intended for oral administration. The drug has an effect on the functioning of the nervous system and allows you to restore neuromuscular patency. The drug is often prescribed to young children for various diseases of the musculoskeletal system. The product is recommended for periodic use in a course lasting 1-2 weeks.
Combilipen
Combilipen can be considered as a full-fledged drug that provides analgesic effect. This ability is explained by the inclusion of lidocaine in the tablets.
Pentovit
The vitamin preparation Pentovit contains B vitamins and other components that have a positive effect on the functioning of the human body. The product is highly effective and safe. The composition is well tolerated and can be prescribed to patients of all age groups.
Reviews
In general, patient reviews of the drug are positive. They note that after 2-3 days of taking it, sleep normalizes, the emotional state improves, and a feeling of cheerfulness and lightness appears.
In addition, in combination with massages and physical therapy, the drug helps with back and neck pain that accompanies people with a sedentary lifestyle.
They describe an improvement in the condition of hair and nails after using the vitamin complex.
Patients write that the positive effect of the drug lasts for 2-3 months after completion of use.
Negative reviews are only given to persons with individual intolerance to the components of Neurovitan.
You can also read reviews at the end of the article.