Orsoten for weight loss: action and side effects

• July 9, 2019
• Other drugs
• Valieva Olga

Finding a slim figure and getting rid of fat deposits is the cherished dream of many girls. There are also many men who want to lose weight. Often people are ready to take any drugs just to achieve the physique of their dreams. "Orsoten Slim" is a relatively safe remedy that can help you get rid of fat deposits on the body. The extra pounds will go away slowly but surely. Orsoten Slim capsules are an inexpensive and proven means by hundreds of thousands of people to achieve the figure of their dreams.

Composition and release form

The main active ingredient of the drug is a substance called orlistat. The release form is capsules; Orsoten Slim is not available in tablets; there is also no injection form. It is recommended to swallow the capsules whole with a small amount of water. The capsule cannot be halved or the powder inside without the shell consumed, since in this case the effect of the drug practically disappears.

What is the difference between the drugs “Orsoten” and “Orsoten Slim”? The amount of active ingredient in the capsule. One Orsoten capsule contains 120 mg of orlistat, and Orsoten Slim contains 60 mg. This does not make the second drug worse and does not detract from its effect, you just need to take two capsules if necessary. However, reviews from patients and doctors report that in most cases it is enough to take one capsule with 60 mg of the active substance three times a day.

Analogs

Level 4 ATX code matches:

• Allie
• Xenical
• Xenalten
• Orlistat

Analogues of the drug Orsoten are the drugs Xenical , Orlistat , Orsoten Slim , Orlimax , Xenalten , etc. When choosing such drugs, it is recommended to consult a doctor. You should not be guided solely by the cost of the drug. In addition, some drugs have a higher cost. In particular, Xenical capsules will cost an average of 900 rubles. for 21 capsules, while the price of Xenical’s analogue, the drug Orsoten, is approximately 650 rubles for 21 capsules.

Xenical or Orsoten - which is better?

Reviews indicate that there is no clear answer to this question. The effectiveness of Orsoten and Xenical on the body depends on how correct and regular the capsules are taken, whether the person plays sports, and whether he follows a diet. Both drugs are used in the complex treatment of obesity. Both drugs belong to the same pharmacological group, have a similar active ingredient and are inhibitors of gastrointestinal lipases. The doctor will help you determine which drug should be chosen by assessing the individual characteristics of the person and his problems.

Which is better: Orsoten or Reduxin?

Conditions for dispensing from pharmacies

The drug is available with a prescription. However, many pharmacists, knowing that the drug relatively rarely causes side effects and there is no threat to life when taking it, often neglect the dispensing rule. So in small pharmacies it is quite possible to purchase the drug without having a prescription from a doctor.

The cost of a package with 42 capsules is about two thousand rubles. This amount of medicine will last about 10-12 days. If obesity is severe, you will have to take more capsules, and the package will only last for 5-7 days. So, when deciding to lose excess weight with the help of this drug, calculate in advance the cost of the course, the duration of which should not be less than two months. Financially, the drug is quite expensive.

pharmachologic effect

How does the drug work, why is it prescribed for obesity and weight problems? The instructions for Orsoten Slim state that orlistat has the unique ability to “disarm” fats that enter the human body with food. Thus, if you drink a capsule immediately after a meal, the fat simply will not be absorbed. On average, patients using this drug lose 4-8 kg, this is confirmed by numerous reviews.

The instructions for Orsoten Slim indicate that a day after taking the capsule, the concentration of fat in the patient’s excrement increases. From the moment the drug is discontinued, the concentration returns to normal after 72 hours, in some cases earlier.

If the patient's body mass index is more than 28 kg/m2, then you should consider increasing the dosage (for example, take two capsules after each meal). This point should be discussed with an endocrinologist or nutritionist. Of course, the patient should adjust his diet and increase physical activity. This comprehensive treatment of obesity will give a stable result. If you just take the capsules and do not instill new eating habits in yourself, then after stopping the drug, the excess weight will return very quickly.

Orlistat is practically not absorbed into the blood from the gastrointestinal tract and is excreted in the feces. It is minimally able to penetrate red blood cells. Significantly binds to blood proteins. About 97% of the substance is excreted through the intestines, including 83% as unchanged orlistat. About 2% of orlistat ingested is excreted by the kidneys (urine). Complete elimination from the body occurs after 3-5 days.

Orsoten Slim 60 mg caps. No. 42 76613

Description

Orsoten® slim KRKA (Slovenia) capsules 60 mg; contour packaging 21, cardboard pack 2; No. LP-000301, 2011-02-17 from KRKA-Rus (Russia) Latin name Orsoten® slim Active ingredient Orlistat* (Orlistatum) ATC: A08AB01 Orlistat Pharmacological group Gastrointestinal lipase inhibitor [Other lipid-lowering drugs] Nosological classification (ICD -10) E66 Obesity Description of the dosage form Capsules. Solid, gelatin No. 3. Body - white; The lid is light yellow. The contents of the capsules are microgranules or a mixture of powder and microgranules of white or almost white color. The presence of compacted agglomerates that easily crumble when pressed is allowed. Pharmacological action Pharmacological action - inhibiting gastrointestinal lipases. Pharmacodynamics Orlistat is a potent, specific, long-acting inhibitor of gastrointestinal lipases. It exhibits its therapeutic activity in the lumen of the stomach and small intestine, forming a covalent bond with the active serine site of gastric and pancreatic lipases. An inactivated enzyme loses the ability to hydrolyze dietary fats (triglycerides) into absorbable free fatty acids and monoglycerides. Unbroken triglycerides are not absorbed, which leads to a decrease in the number of calories absorbed by the body and loss of body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation. According to the results of clinical studies, orlistat, taken daily at a dose of 60 mg 3 times a day, blocks the absorption of approximately 25% of the fats included in the daily diet. Along with a decrease in body weight, with long-term use of orlistat at a dose of 60 mg, there is a decrease in such indicators as waist circumference, the concentration of total cholesterol (TC) and the concentration of low-density lipoprotein cholesterol (LDL-C) in the blood plasma. After 6 months of therapy with orlistat at a dose of 60 mg, the average concentration of total cholesterol in the blood plasma decreases by an average of 2.4%, and LDL cholesterol by 3.5%. After 6 months of taking the drug, waist circumference decreases by an average of 4.5 cm. Pharmacokinetics Absorption. Absorption of the drug is minimal. Distribution. Vd cannot be determined because orlistat is minimally absorbed and has no established systemic pharmacokinetics. Orlistat is more than 99% bound to plasma proteins (mainly lipoproteins and albumins). Orlistat can penetrate into red blood cells to a minimal extent. Metabolism. Metabolism of orlistat occurs mainly in the walls of the stomach and small intestine. Excretion. About 97% of the drug dose taken orally is excreted through the intestines, 83% of this amount is unchanged. Excretion of orlistat and its metabolites by the kidneys is less than 2% of the dose taken. The drug is completely eliminated after 3–5 days. The elimination of orlistat is similar in volunteers with normal body weight and in obese patients. Indications for Orsoten® slim: Weight loss in adults (over 18 years of age) with excess body weight (BMI >28 kg/m2). Use only in combination with a moderate hypocaloric diet with low fat content. Contraindications: hypersensitivity to orlistat or to any of the components of the drug; chronic malabsorption syndrome; cholestasis; concomitant therapy with cyclosporine; simultaneous use of indirect anticoagulants (warfarin); simultaneous use of sitagliptin; pregnancy; breastfeeding period; age up to 18 years. Use during pregnancy and breastfeeding Orsoten® slim should not be used during pregnancy due to the lack of reliable clinical data confirming the safety of its use. It has not been established whether orlistat passes into breast milk, and therefore the use of Orsoten® Slim during breastfeeding is not recommended. Side effects Adverse reactions (ARs) when taking Orsoten® slim are usually observed in the gastrointestinal tract and are caused by the pharmacological action of the drug. Classification of the frequency of side effects, recommended by WHO: very often - ≥1/10; often - from ≥1/100 to <1/10; uncommon - from ≥1/1000 to <1/100; rarely - from ≥1/10000 to <1/1000; very rarely - <1/10000; frequency unknown—cannot be estimated from available data. The frequency of reactions from various organs and systems is indicated below. Clinical studies examining the use of orlistat at a dose of 60 mg for a duration of 18 to 24 months identified adverse reactions from the gastrointestinal tract, which were generally mild and reversible. They usually appeared at the beginning of treatment. Following a low-fat diet reduces the likelihood of such reactions. From the gastrointestinal tract: very often - oily discharge from the rectum, passage of gases with some discharge, imperative urge to defecate, steatorrhea; often - abdominal pain, fecal incontinence, loose stools, increased bowel movements. As a rule, these adverse reactions are mild and transient. They occur in the early stages of treatment (in the first 3 months of therapy), and most patients had no more than one episode of such reactions. Post-registration studies During the post-registration use of orlistat, the following adverse reactions were observed, the frequency of which is unknown. From the hematopoietic organs: a decrease in the concentration of prothrombin and an increase in the INR in the blood plasma in patients taking orlistat simultaneously with indirect anticoagulants. From the gastrointestinal tract: minor bleeding from the rectum, diverticulitis. From the skin and subcutaneous tissue: bullous rash. From the immune system: hypersensitivity reactions, including pruritus, skin rash, urticaria, angioedema, bronchospasm and anaphylaxis. From the liver and biliary tract: cholelithiasis, hepatitis, increased activity of liver transaminases and alkaline phosphatase in the blood plasma. Interaction Cyclosporine. Several drug interaction studies of cyclosporine, when administered concomitantly with orlistat, reported a decrease in cyclosporine plasma concentrations. This could potentially lead to a decrease in the immunosuppressive effectiveness of the latter. The simultaneous use of Orsoten® slim and cyclosporine is contraindicated. Indirect anticoagulants. When warfarin or other oral anticoagulants are used simultaneously with Orsoten® slim, INR values ​​may change. Fat-soluble vitamins. Taking Orsoten® slim may potentially impair the absorption of fat-soluble vitamins (A, D, E, K and beta-carotene). Acarbose. Given the lack of studies examining pharmacokinetic interactions, it is not recommended to use Orsoten® slim simultaneously with acarbose. Amiodarone. When used simultaneously with orlistat, a decrease in the concentration of amiodarone in the blood plasma was observed after a single dose. The clinical significance of this effect in patients taking amiodarone is unclear. The simultaneous use of Orsoten® slim and amiodarone is possible only on the recommendation of a doctor. Lack of interaction. Orlistat does not interact with amitriptyline, phenytoin, fluoxetine, sibutramine, phentermine, atorvastatin, pravastatin, fibrates, biguanides, digoxin, nifedipine, losartan and ethanol. Overdose When using orlistat at a dose of 800 mg once and at a dose of up to 400 mg 3 times a day, daily, for 15 days, no significant adverse reactions were detected in both patients with normal body weight and in obese patients. When using orlistat 240 mg 3 times a day for 6 months, no increase in the frequency of adverse reactions was noted. Most post-marketing reports of orlistat overdose either lack specific information about adverse reactions or describe adverse reactions that are not different from those observed with recommended doses of orlistat. In case of overdose, consult a doctor. In case of significant overdose of orlistat, it is recommended to monitor the patient for 24 hours. Based on data from human and animal studies, all systemic effects of orlistat due to lipase inhibition are usually quickly reversible. Special instructions Diet and exercise are an integral part of a weight loss program. It is recommended to begin a dietary program and exercise before starting therapy with Orsoten® slim. While taking Orsoten® slim, you must adhere to a fractional, balanced, moderately hypocaloric diet, with a fat content of no more than 30% of the daily calorie intake (for example, with a diet of 2000 kcal/day, fat intake should be no more than 66 g/day). You should adhere to the recommendations received regarding diet and physical activity both during and after stopping the drug. The use of Orsoten® slim leads to an increase in fat content in feces already 24–48 hours after the start of administration. After stopping the use of Orsoten® Slim, the fat content in the stool usually returns to its original level within 48–72 hours. Following a low-fat diet reduces the likelihood of gastrointestinal side effects. Taking orlistat may potentially impair the absorption of fat-soluble vitamins (A, D, E, K and beta-carotene). The vast majority of patients receiving orlistat during the four-year clinical studies had concentrations of vitamins A, D, E, K and beta-carotene within the normal range. For preventive purposes, it is recommended to take multivitamins at night. Since weight loss is usually accompanied by an improvement in carbohydrate metabolism, patients with type 2 diabetes mellitus should consult a doctor before starting therapy with Orsoten® Slim and, if necessary, adjust the dose of hypoglycemic drugs. A decrease in body weight during treatment may be accompanied by a decrease in blood pressure and TC concentration in the blood plasma. Patients taking antihypertensive or lipid-lowering drugs should consult a doctor and, if necessary, adjust the dose of these drugs. In clinical studies, no interaction was observed between oral contraceptives and orlistat. However, orlistat may indirectly reduce the bioavailability of oral contraceptives, which may lead to the development of unwanted pregnancy. It is recommended to use additional methods of contraception in case of acute diarrhea. Patients suffering from kidney disease should consult a doctor, as hyperoxaluria and nephropathy may develop. Patients taking amiodarone, warfarin or other oral anticoagulants should also consult a physician before starting orlistat therapy as changes in the INR may occur. Patients should stop taking Orsoten® slim and consult a doctor if symptoms occur: icteric discoloration of the sclera or skin, itching, dark urine and loss of appetite. Impact on the ability to perform potentially hazardous activities that require special attention and quick reactions (for example, driving, working with moving mechanisms). The drug Orsoten® slim does not affect the ability to drive a car, other types of vehicles or use machinery. Release form Capsules, 60 mg. 21 caps. in blister packs made of combined PVC/PVDC material and aluminum foil. 2 or 4 blister packs are packed in a cardboard pack. . 143500, Russia, Moscow region, Istra, st. Moskovskaya, 50; in cooperation with JSC "KRKA, d.d., Novo Mesto". Šmarješka cesta 6, 8501 Novo Mesto, Slovenia. Tel.; Fax. Representative office of JSC "KRKA, d.d., Novo Mesto" in the Russian Federation/organization receiving consumer complaints: 125212, Moscow, Golovinskoye Shosse, 5, bldg. 1, fl. 22. Tel.; fax (495) 981-10-90. Conditions for dispensing from pharmacies Without a prescription. Storage conditions for Orsoten® slim At a temperature not exceeding 25 °C, in the original packaging. Keep out of the reach of children. The shelf life of Orsoten® slim is 3 years. Do not use after the expiration date stated on the package. 2000-2015. Register of Medicines of Russia The database is intended for healthcare professionals. Commercial use of materials is not permitted.

Possible product names

• Orsoten Slim 60 mg caps. No. 42
• ORSOTENE SLIM 60 MG CAPS. No. 42
• ORSOTENE SLIM 0.06 N42 CAPS
• ORSOTENE SLIM CAPS. 60 MG X42
• ORSOTENE SLIM CAPS. 60 MG No. 42
• ORSOTENE SLIM 60MG CAPS. X42
• (Orsoten slim) Orsoten Slim 60 mg caps. No. 42

Indications for use

The instructions for Orsoten Slim indicate that the drug is used for the following diseases and conditions:

• bulimic neurosis (in this case it is advisable to use the drug in complex therapy with antidepressants with anorexigenic effect);
• nutritional obesity;
• obesity caused by type 2 diabetes mellitus.

However, very often the drug is taken by overweight girls who have not yet been diagnosed with obesity. It is clear that it is better to pull yourself together and stick to proper nutrition - this is the best way to lose weight. However, if for some reason you cannot eat less, then it is permissible to use drugs containing orlistat to prevent weight gain.

special instructions

When taking the drug, patients must adhere to a special diet.

If the diet contains a large amount of fat, then the likelihood of developing adverse reactions from the digestive tract increases.

When treated with Orsoten Slim, vitamins should be taken before bedtime.

Patients with diabetes mellitus receiving hypoglycemic drugs should consult with their doctor before starting to use this drug, since weight loss may lead to improved metabolism, and therefore may require dose adjustment of hypoglycemic drugs.

Patients taking drugs against hypercholesterolemia or arterial hypertension should also consult a doctor before starting treatment with Orsoten Slim, since weight loss can improve blood pressure and cause a decrease in cholesterol levels.

If rectal bleeding occurs, you should consult a doctor.

If diarrhea occurs while taking the drug, additional methods of contraception should be used.

Possible side effects

While taking medications containing orlistat, the following side effects may develop:

• the appearance of oily discharge from the rectum (this is due to the fact that incompletely digested and assimilated fat from food comes out);
• bloating, pain in the epigastric region;
• fecal incontinence, diarrhea, sudden urgency to defecate;
• decrease in the amount of prothrombin in the general blood test;
• an increase in INR values ​​when taking blood tests;
• the appearance of a bullous rash on the skin;
• bronchospasm, anaphylaxis;
• hepatitis, exacerbation of cholelithiasis, cholecystitis, diverticulitis;
• increased liver parameters when taking blood tests.

Reviews of those losing weight about Orsoten Slim report that taking the drug is almost always accompanied by the development of more or less pronounced side effects. Alas, the most unpleasant one almost always appears - discharge from the rectum. Since they are incompletely digested fat from food, the sphincter is not able to contain the secretions.

Reviews often mention that people are forced to attach special pads to their underwear, since grease stains can appear on clothes. Nevertheless, obese patients continue therapy with Orsoten, despite such an unpleasant side effect, since the desired result exceeds the inconvenience of taking it. Orlistat is a substance that, regardless of the form of release, always gives similar side effects.

Comparison of Xenical and Orsoten

Xenical and Orsoten are similar to each other, but have some differences. You can compare products in more detail by price, effectiveness and other indicators.

Similarities

Both drugs are used in the treatment of obesity. The composition and pharmacological properties are identical. Release form: capsules. The drugs are prescribed as a supplement to a hypocaloric diet in cases of excess body fat (including type 2 diabetes mellitus) and in obese patients (BMI ≥30 kg/m²).

Both drugs are used in the treatment of obesity.

Both preparations contain microcrystalline cellulose. Dietary fiber reduces appetite, stimulates peristalsis, adsorbs toxins, cholesterol, and bacteria.

The recommended dosage is 120 mg (1 capsule) before each meal. But there are some contraindications for use:

• pregnancy and breastfeeding;
• impaired absorption of nutrients in the intestine;
• cholestatic syndrome;
• allergy to components;
• children's age up to 12 years.

Side effects may include gastrointestinal disorders, allergic reactions, hypoglycemia, anxiety, headaches and menstrual irregularities.

Orsoten and Xenical are contraindicated if you are allergic to the components.

Orsoten and Xenical are contraindicated during breastfeeding.

What is the difference

Xenical is produced in Switzerland, and Orsoten is produced in Russia. Xenical, unlike the generic, contains sodium lauryl sulfate. The food additive can cause allergic reactions and, with prolonged use, has a negative effect on the body. The analogue is safer for people who have impaired functioning of the liver and kidneys or are prone to allergies. Capsules differ in color and cost per package.

Which is cheaper?

The price of the drug Xenical is from 900 rubles. The cost of the analogue is from 750 rubles.

Contraindications for use

Instructions for use for Orsoten Slim indicate that there are the following contraindications for use:

• orlistat intolerance;
• cholestasis, cholecystitis, liver diseases;
• childhood and adolescence.

You should take Orsoten and other drugs with orlistat with caution if you have the following diagnoses and conditions:

• diabetes;
• hypothyroidism;
• disturbances in the exchange of intercellular fluid;
• epilepsy;
• kidney and gallbladder diseases.

Optimal dosage

The instructions for using Orsoten Slim are as follows:

• for alimentary obesity - one capsule after breakfast, lunch and dinner (no later than 60 minutes after a meal), washed down with water or other liquid;
• for obesity caused by a sedentary lifestyle or metabolic disorders, you should take from 60 to 120 mg. orlistat, which is equivalent to one and two capsules of the drug, respectively.

If for one reason or another the patient missed a meal, the capsule should not be taken. The instructions indicate that during treatment with the drug you should reduce the amount of fatty foods you eat. The higher the proportion of fat in the diet, the higher the likelihood of side effects.

The maximum amount of orlistat per day that can be consumed without the risk of side effects is 450 mg. However, some patients note that the release of fat from the rectum begins even if only 200 mg is consumed per day. orlistat. Doctors explain this by saying that there is too much fat in the diet, so the drug is simply not able to “work” as intended by the manufacturer. If the patient's body weight decreases by less than 5% over 12 weeks, therapy with orlistat should be discontinued.

Drug interactions

When orlistat is taken simultaneously with cyclosporine, a decrease in the latter in the blood plasma is observed. As a result of this interaction, the immunosuppressive activity of cyclosporine is reduced. Therefore, the simultaneous use of such drugs is contraindicated.

The simultaneous use of orlistat and warfarin (or other anticoagulants) also subsequently leads to changes in INR values.

If a person takes vitamin-mineral complexes, then it should be taken into account that while taking orlistat, a violation of the absorption of fat-soluble vitamins develops.

When taking orlistat simultaneously with drugs from the group of antidepressants (they are also often prescribed in complex therapy for bulimic disorders leading to obesity), there is no increase or decrease in the effect of any of the drugs. So such a combination is possible if the attending physician considers such a complex appropriate.

Results of taking the drug

“Orsoten”, “Orsoten Slim” and “Ortoslim” for weight loss (as well as other analogues containing orlistat) - all these drugs act on the same principle: minimizing the absorption of fats from food. As a result, the body receives fewer calories, although the person eats almost the same as before. Due to such an unintentional reduction in calories, weight loss does not occur very quickly, but it is inevitable and relatively safe for health.

Reviews from people losing weight about the effect of drugs containing orlistat are different. Negative reviews are usually due to people expecting weight loss too quickly. Alas, with nutritional obesity, losing extra pounds is not very fast. A normal and safe weight loss is considered to be a loss of 3-7 kg per month. The result also depends on what your initial body mass index was. If obesity was of an initial degree, then it is quite natural that a person losing weight will lose only 2-4 kilograms per month, even if he adjusts his diet while undergoing Orsoten Slim therapy.

Characteristics of Orsoten

The drug is available in the form of capsules taken orally.
The active ingredient is orlistat, at a dosage of 120 mg. An additional component of the capsule contents is microcellulose. The shell consists of water, hypromellose, substances E171 and E172. Under the influence of orlistat, lipases are inhibited - enzymes responsible for the digestion and breakdown of fats that enter the body with food. As a result of regular use of the drug, weight decreases.

The indication for the use of Orsoten is obesity. While taking the medication, you should follow a low-calorie diet. For people suffering from type 2 diabetes, Orsoten can be prescribed along with hypoglycemic medications.

The drug has a number of contraindications:

• individual intolerance to the components of the drug;
• problems with the absorption of nutrients in the small intestine (malabsorption);
• cholestasis;
• pregnancy and breastfeeding;
• age up to 18 years.

While taking Orsoten, side effects sometimes develop in the form of frequent bowel movements or false urge to defecate, and fecal incontinence. Patients often complain of oily discharge from the anus and flatulence. Unpleasant symptoms occur more often in those people who eat fatty foods. If you change your taste preferences, then side effects will be observed less frequently.

The recommended single dose is 120 mg. Capsules should be taken before meals 3 times a day. You should not increase the dosage, as this will not lead to an increase in the therapeutic effect.

While taking Orsoten, side effects sometimes develop in the form of frequent bowel movements or false urge to defecate, and fecal incontinence.

Reviews from doctors about the effect of the drug

You should not take the medicine if the side effects listed in the instructions for use occur. Reviews of Orsoten Slim from doctors are positive. But doctors emphasize that if the drug is poorly tolerated, then it is better to stop taking it altogether.

Doctors also believe that the use of drugs with orlistat in the long term is much safer for health than harsh and strict mono-diets, hunger strikes and other imbalances in nutrition. Yes, the rate of weight loss when taking capsules is slow, but there is no detrimental effect on health.

Which drug is more effective from this line?

Reduxin is another drug that is recommended to be taken for weight loss. But, unlike the drugs Xenical, Orsoten or Xenalten, Reduxin affects the brain.

Reduxin actively suppresses the feeling of hunger, resulting in less food consumed.

Reduxin allows you to slowly lose weight (about 0.5 - 1 kg per week), so it is not suitable for those who want to urgently lose weight for the New Year.

In this, Reduxin is similar to the drugs Xenical for weight loss or Orsoten, which also require a long time to achieve an effect.

Cornelia Mango loses weight on reduxin

Reduxin contains the substance sibutramine: it is not addictive and safe. However, like any medicine, Reduxin has contraindications.

It is better not to take Reduxin:

1. - with liver and kidney failure;
2. - hypertension;
3. - IHD;
4. - glaucoma;
5. - mental disorders;
6. - heart disease;
7. - eating disorders;
8. - addiction to nicotine and alcohol.

Reduxin has minor side effects that may affect heart rate and blood pressure.

Thus, Xenical and Reduxin are similar to each other in that they are relatively safe means of losing weight.

Reduxin is preferable for those who cannot afford regular uncontrolled bowel movements, as is the case with Xenical.

Reduxin only reduces appetite, so for those who lead an active lifestyle and want to lose weight, it is better to choose it. Photos of people who have lost weight best prove this.

Xenical and Reduxin, although different in their composition and method of action, are drugs recommended by doctors.

If you really need to lose weight with medications, it is better to choose those that have undergone medical research and try to avoid drugs with conflicting reviews.

Olga Kartunkova, who lost 49 kg, shocked the audience: “I burned off all the normal fat...

jslim.ru

Drugs with similar effects

If for one reason or another you cannot purchase Orsoten Slim, then pay attention to its analogues, which also contain orlistat:

• "Xenical";
• "Orsoten";
• "Orlimax";
• "Xenalten."

The amount of active ingredient in the capsule varies in different drugs, so you should think about what the dosage will be. If you are unsure whether to take this drug, consult an endocrinologist or nutritionist. As a rule, doctors have a positive attitude towards this type of therapy and listen to the opinions of patients when prescribing.

Doctors' opinion

Nutritionists believe that the treatment of obesity can be done without medications. However, the same experts do not reject the benefits of taking medications in order to lose excess weight. However, the latter is applicable for obese people (BMI greater than 30).

What's better

No doctor can predict which pharmacological agent is more effective. Both are supposed to be good.

The main thing is to follow the recommendations and then the effect of taking medications will not take long:

• It is worth paying attention to the body mass index. It is the BMI indicators that provide information about whether the medicine should be used or not. Using it, the doctor determines and prescribes the required dose of the component.
• A prerequisite while taking the medicine is to adhere to an appropriate diet. The absence of the latter will not give the long-awaited result, and the money will be wasted.
• Therapy based on lipase inhibitors adversely affects the absorption of fat-soluble vitamins from foods. Nutritionists recommend including multivitamins in your diet to avoid the consequences of vitamin deficiency. In addition, they should be taken before bedtime, when the effect of orlistat has decreased.
• A history of diabetes mellitus should also be taken into account during treatment. Taking medications to promote weight loss involves improving the metabolic process, which can have a positive effect on the functioning of the pancreas. At the same time, the dependence on taking glucose-lowering drugs, including insulin, changes. In this case, the treatment regimen by the endocrinologist is subject to correction. This also applies to patients suffering from atherosclerosis and.
• If the patient is being treated with other medications (anticoagulants, antiarrhythmics, etc.), then before starting orlistat you should consult a specialist.
• Weight loss medications can reduce the effect of hormonal pills that prevent pregnancy. Therefore, other possible methods of contraception should be reconsidered.

Comparison

The difference in the content of the main component is due to the individual approach to the patient. A patient with first-degree obesity will first be prescribed a drug with a low concentration of orlistat. In more severe cases, the dose of the substance is increased.

Detection of side effects to one of the drugs requires withdrawal from both, since they are the same in both.

Reviews

Kartotskaya V.M., gastroenterologist:

Orsoten is my assistant in the fight against obesity. In addition, the patients never complained, but only came and pleased with their successes.

Artamanenko I. S., nutritionist:

Although Orsoten Slim has side effects, it helps. If you act strictly according to the recommendations and do not violate the diet, then no complications will follow.